一般描述
Awater-soluble embedding medium for EM based on an aliphatic polyepoxide.
应用
Durcupan™ACM, single component A, M epoxy resin has been used for:
- A method to prepare large resin sections for counting myelinated axons in rodent CNS and PNS structures.: This study presents a technique using Durcupan ACM for preparing large resin sections, enhancing the analysis of myelinated axons in rodent central and peripheral nervous systems.
- Three-dimensional immersive virtual reality for studying cellular compartments in 3D models from EM preparations of neural tissues.: This research utilizes Durcupan ACM in electron microscopy to create 3D models of neural tissues, facilitating studies via immersive virtual reality.
- Long-term effect of prazosin and losartan administration on blood pressure, heart, carotid artery, and acetylcholine induced dilation of cardiovascular system of young Wistar rats and SHR.: Explores the cardiovascular effects in rats using Durcupan ACM embedded samples for detailed tissue analysis.
- Embedding material for electron microscopy on the basis of Araldite®.
特点和优势
Mixtures of Durcupan ACM present an interesting alternativeto methacrylates for embedding sections for electron microscopy. They presentthe advantage that they harden uniformly, practically without shrinkage.All fixing agents normally used for electronmicroscopic work are also suitable for the Durcupan ACM embedding process. Thisprocess consists of three phases: dehydration of the tissue with acetone orethyl alcohol (1), infiltration with the embedding agent, followed byhardening.
法律信息
Araldite is a registered trademark of Huntsman Advanced Materials Inc.
Durcupan is a trademark of Sigma-Aldrich Chemie GmbH
警示用语：
Warning
危险分类
Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1
储存分类代码
10 - Combustible liquids
WGK
WGK 2
闪点(°F)
377.6 °F
闪点(°C)
192 °C
个人防护装备
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
A method to prepare large resin sections for counting myelinated axons in rodent CNS and PNS structures
Dzurjaskova Z, et al.
Neuroscience Letters, 750, 135767-135767 (2021)
Three-dimensional immersive virtual reality for studying cellular compartments in 3D models from EM preparations of neural tissues
Cali C, et al.
The Journal of Comparative Neurology, 524(1), 23-38 (2016)
Long-term effect of prazosin and losartan administration on blood pressure, heart, carotid artery, and acetylcholine induced dilation of cardiovascular system of young Wistar rats and SHR
Kristek F, et al.
General Physiology and Biophysics, 32(2), 235?243-235?243 (2013)
Tin Ki Tsang et al.
eLife, 7 (2018-05-12)
Electron microscopy (EM) offers unparalleled power to study cell substructures at the nanoscale. Cryofixation by high-pressure freezing offers optimal morphological preservation, as it captures cellular structures instantaneously in their near-native state. However, the applicability of cryofixation is limited by its
Lu Gan et al.
Frontiers in immunology, 8, 1507-1507 (2017-12-19)
Leptin is an adipocyte-derived hormone and maintains adipose function under challenged conditions. Autophagy is also essential to maintain cellular homeostasis and regulate characteristics of adipose tissue. However, the effects of leptin on autophagy of adipocyte remain elusive. Here, we demonstrated
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