一般描述
Awater-soluble embedding medium for EM based on an aliphatic polyepoxide.
应用
Durcupan™ACM, single component C, accelerator 960 (DY 060) has been used for:
- A method to prepare large resin sections for counting myelinated axons in rodent CNS and PNS structures.: This study presents a technique using Durcupan ACM for preparing large resin sections, enhancing the analysis of myelinated axons in rodent central and peripheral nervous systems.
- Three-dimensional immersive virtual reality for studying cellular compartments in 3D models from EM preparations of neural tissues.: This research utilizes Durcupan ACM in electron microscopy to create 3D models of neural tissues, facilitating studies via immersive virtual reality.
- Long-term effect of prazosin and losartan administration on blood pressure, heart, carotid artery, and acetylcholine induced dilation of cardiovascular system of young Wistar rats and SHR.: Explores the cardiovascular effects in rats using Durcupan ACM embedded samples for detailed tissue analysis.
- Embedding material for electron microscopy on the basis of Araldite®.
特点和优势
Mixtures of Durcupan ACM present an interesting alternative to methacrylates for embedding sections for electron microscopy. They present the advantage that they harden uniformly, practically without shrinkage. All fixing agents normally used for electronmicroscopic work are also suitable for the Durcupan ACM embedding process. This process consists of three phases: dehydration of the tissue with acetone or ethyl alcohol, infiltration with the embedding agent, followed by hardening.
法律信息
Araldite is a registered trademark of Huntsman Advanced Materials Inc.
Durcupan is a trademark of Sigma-Aldrich Chemie GmbH
警示用语：
Danger
危险声明
危险分类
Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B
储存分类代码
8A - Combustible, corrosive hazardous materials
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
法规信息
监管及禁止进口产品
此项目有
Three-dimensional immersive virtual reality for studying cellular compartments in 3D models from EM preparations of neural tissues
Cali C, et al.
The Journal of Comparative Neurology, 524(1), 23-38 (2016)
Long-term effect of prazosin and losartan administration on blood pressure, heart, carotid artery, and acetylcholine induced dilation of cardiovascular system of young Wistar rats and SHR
Kristek F, et al.
General Physiology and Biophysics, 32(2), 235?243-235?243 (2013)
A method to prepare large resin sections for counting myelinated axons in rodent CNS and PNS structures
Dzurjaskova Z, et al.
Neuroscience Letters, 750, 135767- 135767 (2021)
Tin Ki Tsang et al.
eLife, 7 (2018-05-12)
Electron microscopy (EM) offers unparalleled power to study cell substructures at the nanoscale. Cryofixation by high-pressure freezing offers optimal morphological preservation, as it captures cellular structures instantaneously in their near-native state. However, the applicability of cryofixation is limited by its
Keun-Young Kim et al.
Cell reports, 29(3), 628-644 (2019-10-17)
The form and synaptic fine structure of melanopsin-expressing retinal ganglion cells, also called intrinsically photosensitive retinal ganglion cells (ipRGCs), were determined using a new membrane-targeted version of a genetic probe for correlated light and electron microscopy (CLEM). ipRGCs project to
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