一般描述
Awater-soluble embedding medium for EM based on an aliphatic polyepoxide.
应用
Durcupan™ACM, single component D has been used for:
- A method to prepare large resin sections for counting myelinated axons in rodent CNS and PNS structures.: This study presents a technique using Durcupan ACM for preparing large resin sections, enhancing the analysis of myelinated axons in rodent central and peripheral nervous systems.
- Three-dimensional immersive virtual reality for studying cellular compartments in 3D models from EM preparations of neural tissues.: This research utilizes Durcupan ACM in electron microscopy to create 3D models of neural tissues, facilitating studies via immersive virtual reality.
- Long-term effect of prazosin and losartan administration on blood pressure, heart, carotid artery, and acetylcholine induced dilation of cardiovascular system of young Wistar rats and SHR.: Explores the cardiovascular effects in rats using Durcupan ACM embedded samples for detailed tissue analysis.
- Embedding material for electron microscopy on the basis of Araldite®.
特点和优势
Mixtures of Durcupan ACM present an interesting alternativeto methacrylates for embedding sections for electron microscopy. They presentthe advantage that they harden uniformly, practically without shrinkage.All fixing agents normally used for electronmicroscopic work are also suitable for the Durcupan ACM embedding process. Thisprocess consists of three phases: dehydration of the tissue with acetone orethyl alcohol (1), infiltration with the embedding agent, followed byhardening.
法律信息
Araldite is a registered trademark of Huntsman Advanced Materials Inc.
Durcupan is a trademark of Sigma-Aldrich Chemie GmbH
警示用语：
Danger
危险声明
危险分类
Aquatic Acute 1 - Aquatic Chronic 2 - Repr. 1B
储存分类代码
6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
闪点(°F)
367.7 °F - open cup
闪点(°C)
186.5 °C - open cup
个人防护装备
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
法规信息
农药列管产品
Three-dimensional immersive virtual reality for studying cellular compartments in 3D models from EM preparations of neural tissues
Cali C, et al
The Journal of Comparative Neurology, 524(1), 23-38 (2016)
A method to prepare large resin sections for counting myelinated axons in rodent CNS and PNS structures
Dzurjaskova Z, et al.
Neuroscience Letters, 750, 135767-135767 (2021)
Long-term effect of prazosin and losartan administration on blood pressure, heart, carotid artery, and acetylcholine induced dilation of cardiovascular system of young Wistar rats and SHR
Kristek F, et al.
General Physiology and Biophysics, 32(2), 235?243-235?243 (2013)
Noemi Holderith et al.
Cell reports, 32(4), 107968-107968 (2020-07-30)
Elucidating the molecular mechanisms underlying the functional diversity of synapses requires a high-resolution, sensitive, diffusion-free, quantitative localization method that allows the determination of many proteins in functionally characterized individual synapses. Array tomography permits the quantitative analysis of single synapses but
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