biological source
rabbit
conjugate
unconjugated
antibody form
culture supernatant
antibody product type
primary antibodies
clone
EP381, monoclonal
description
This product is intended for research use only. Not for use in diagnostic procedures.
form
buffered aqueous solution
species reactivity
human
packaging
vial of 0.1 mL concentrate Research Use Only (450R-14-RUO)
vial of 1.0 mL concentrate Research Use Only (450R-16-RUO)
vial of 1.0 mL pre-dilute Research Use Only (450R-17-RUO)
vial of 7.0 mL pre-dilute ready-to-use Research Use Only (450R-18-RUO)
manufacturer/tradename
Cell Marque®
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated)
isotype
IgG
control
prostate, prostate carcinoma
shipped in
wet ice
storage temp.
2-8°C
visualization
cytoplasmic
Analysis Note
 IVD |  IVD |  IVD |  RUO |
General description
Prostein is a type IIIA transmembrane protein comprising a cleavable signal peptide and 11 transmembrane domains. In vitro studies demonstrate that prostein transcription and expression is androgen responsive. Prostein expression was found to be restricted to tissues of prostatic origin such as non-neoplastic prostate, prostate lesions, and malignant prostate tissues. Due to its high specificity, immunohistochemical detection of prostein may have utility in distinguishing prostatic carcinoma from the carcinomas of bladder, kidney, lung and colorectum.
Other Notes
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
Physical form
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.
Preparation Note
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Note: This requires a keycode which can be found on your packaging or product label.
Download the latest released IFU
Note: This IFU may not apply to your specific product lot.
Legal Information
Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
法规信息
监管及禁止进口产品
此项目有
Todd Sheridan et al.
The American journal of surgical pathology, 31(9), 1351-1355 (2007-08-28)
Adenocarcinoma of the prostate can present as metastatic carcinoma with no known primary. Prostatic origin can be confirmed in most of these cases by immunohistochemistry for prostate-specific antigen (PSA) and prostate-specific acid phosphatase. In a small subset of high-grade prostate
Michael Kalos et al.
The Prostate, 60(3), 246-256 (2004-06-04)
Prostein is a recently described molecule expressed at the mRNA level in a prostate-specific manner. A murine monoclonal antibody was developed, characterized, and used to evaluate the expression of prostein protein in prostatic, other normal tissue and tumor samples. The
J Xu et al.
Cancer research, 61(4), 1563-1568 (2001-03-14)
In this report, we describe the application of a systematic, genome-based approach to identify prostein, a novel prostate-specific protein expressed in normal and malignant prostate tissues. Characterization of the prostein gene shows that prostein cDNA encodes a 553-amino acid protein.
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