45125
弹性蛋白酶 来源于猪胰腺
lyophilized, powder, white, ~8 U/mg
别名:
弹性蛋白酶 来源于猪胰腺, 胰酞酶 E
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关于此项目
化学文摘社编号:
UNSPSC Code:
12352204
EC Number:
254-453-6
MDL number:
Specific activity:
~8 U/mg
Biological source:
Porcine pancreas
biological source
Porcine pancreas
Quality Level
form
powder
quality
lyophilized
specific activity
~8 U/mg
mol wt
Mr ~25000
impurities
salt, none detected
color
white
storage temp.
−20°C
Biochem/physiol Actions
弹性蛋白酶水解弹性蛋白（弹性纤维的特定蛋白质）并消化血红蛋白、酪蛋白和纤维蛋白。
Other Notes
For protein sequence studies, limited proteolysis; Application in (selective) hydrolysis/condensation of carboxylic ester bonds
一个单元将在 25℃ 下，每分钟，pH8.0，水解 1.0 μmole 的 N-琥珀酰-L-Ala-Ala-Ala-对硝基苯胺。
1 U corresponds to the amount of enzyme which liberates 1 μmol 4-nitroaniline per minute at 25°C and pH 7.8 (succinyl-(L-Ala)3-4-nitroanilide as substrate)
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signalword
Danger
hcodes
Hazard Classifications
Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
常规特殊物品
此项目有
I Grunnet et al.
The Biochemical journal, 209(1), 215-222 (1983-01-01)
Fatty acid synthetase from goat mammary gland was subjected to limited proteolysis by trypsin and elastase. Both proteolytic enzymes selectively cleaved the chain-terminating thioester hydrolase component from the enzyme complex, leaving all other partial activities intact in the core peptides.
T. Sakurai et al.
Journal of the American Chemical Society, 110, 7236-7236 (1988)
Lilibeth A Salvador et al.
Journal of medicinal chemistry, 56(3), 1276-1290 (2013-01-29)
We discovered new structural diversity to a prevalent, yet medicinally underappreciated, cyanobacterial protease inhibitor scaffold and undertook comprehensive protease profiling to reveal potent and selective elastase inhibition. Structure-activity relationship (SAR) studies and X-ray cocrystal structure analysis allowed a detailed assessment
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 45125-1MG | 04061826722800 |