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Merck
CN

45245

曙红5-异硫氰酸酯

≥95.0% (UV)

别名:

EITC

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关于此项目

经验公式(希尔记法):
C21H7Br4NO5S
化学文摘社编号:
分子量:
704.96
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
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assay

≥95.0% (UV)

fluorescence

λex 521; λem 544 (pH 9.0)

storage temp.

2-8°C

SMILES string

OC(=O)c1cc(ccc1C2=C3C=C(Br)C(=O)C(Br)=C3Oc4c(Br)c(O)c(Br)cc24)N=C=S

InChI

1S/C21H7Br4NO5S/c22-12-4-10-14(8-2-1-7(26-6-32)3-9(8)21(29)30)11-5-13(23)18(28)16(25)20(11)31-19(10)15(24)17(12)27/h1-5,27H,(H,29,30)

InChI key

MCXYFYWNOWPDMA-UHFFFAOYSA-N

Application

曙红5-异硫氰酸酯(EITC)是一种荧光探针。在荧光共振能量转移(FRET)测定中,EITC标记的分子可与荧光素-5′-异硫氰酸酯(FITC)标记的分子一起使用。

Other Notes

受体荧光团。测定蛋白质的旋转扩散;用于荧光能量转移研究


pictograms

Health hazard

signalword

Danger

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

存储类别

13 - Non Combustible Solids

wgk

WGK 3

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

flash_point_f

Not applicable

hcodes



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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S Q Liu et al.
The American journal of physiology, 264(5 Pt 1), C1155-C1164 (1993-05-01)
Although eosin-5-maleimide (EM) covalently labels band 3 and has been thought to react at the external-facing anion transport site, EM reversibly inhibits Cl- exchange at 0 degrees C in a noncompetitive fashion, indicating that under these conditions it does not
T Chiba et al.
Biochimica et biophysica acta, 858(1), 107-117 (1986-06-13)
The amino-acid residues of band 3 protein taking part in the ionic interaction with an anion-transport inhibitor, eosin 5-isothiocyanate (EITC), were determined by pH titration. The plots of the absorbance of EITC-ghost system against pH reveal five equilibria, at pH
T J Deerinck et al.
The Journal of cell biology, 126(4), 901-910 (1994-08-01)
A simple method is described for high-resolution light and electron microscopic immunolocalization of proteins in cells and tissues by immunofluorescence and subsequent photooxidation of diaminobenzidine tetrahydrochloride into an insoluble osmiophilic polymer. By using eosin as the fluorescent marker, a substantial