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468R-1

Claudin-4 (EP417) Rabbit Monoclonal Primary Antibody

Name: Claudin-4 (EP417) Rabbit Monoclonal Primary Antibody
Brand: SIGMA

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关于此项目

UNSPSC Code:

12352203

Conjugate:

unconjugated

Clone:

EP417, monoclonal

Application:

IHC (p)

Citations:

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属性

biological source

rabbit

Quality Segment

100, 500

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

EP417, monoclonal

description

For In Vitro Diagnostic Use in Select Regions

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (468R-14), vial of 0.1 mL concentrate Research Use Only (468R-14-RUO), vial of 0.5 mL concentrate (468R-15), vial of 1.0 mL concentrate (468R-16), vial of 1.0 mL concentrate Research Use Only (468R-16-RUO), vial of 1.0 mL pre-dilute Research Use Only (468R-17-RUO), vial of 1.0 mL pre-dilute ready-to-use (468R-17), vial of 7.0 mL pre-dilute ready-to-use (468R-18), vial of 7.0 mL pre-dilute ready-to-use Research Use Only (468R-18-RUO)

manufacturer/tradename

Cell Marque^®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100 (concentrated)

isotype

IgG

control

lung adenocarcinoma

shipped in

wet ice

storage temp.

2-8°C

visualization

membranous

Gene Information

human ... CLDN4(1364)

说明

General description

The claudin-family proteins are a group of tight-junction membranous proteins responsible for paracellular molecular flow between adjacent cells of the epithelium.¹ In normal kidney, claudin-4 plays a key role in paracellular ion reabsorption.² Claudin-4 is expressed in most epithelial cells yet is absent in mesothelial cells, making it of great use in characterizing epithelial malignincies.³ Immunohistochemical identification of this antigen may help identify poorly differentiated lung adenocarcinoma from lesions of mesothelial origin.⁴ Likewise, identification of claudin-4 expression by IHC may be useful in characterizing breast and endometrial lesions.^5,6

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Preparation Note

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Analysis Note

United States - IVD
Canada - IVD
European Union - IVD
Japan - RUO

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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存储类别

12 - Non Combustible Liquids

wgk

WGK 2

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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