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Merck
CN

49549

4-羟基-L-异亮氨酸

≥98.0% (TLC)

别名:

(2S,3R)-2-氨基-4-羟基-3-甲基戊酸

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关于此项目

经验公式(希尔记法):
C6H13NO3
化学文摘社编号:
分子量:
147.17
UNSPSC Code:
12352204
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.32
MDL number:
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产品名称

4-羟基-L-异亮氨酸, ≥98.0% (TLC)

SMILES string

CC(O)[C@H](C)[C@H](N)C(O)=O

InChI key

OSCCDBFHNMXNME-DSDZBIDZSA-N

InChI

1S/C6H13NO3/c1-3(4(2)8)5(7)6(9)10/h3-5,8H,7H2,1-2H3,(H,9,10)/t3-,4?,5-/m0/s1

assay

≥98.0% (TLC)

optical activity

[α]/D +34.0±2.0°, c = 1 in H2O

color

white to off-white

storage temp.

2-8°C

Quality Level

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Biochem/physiol Actions

从胡芦巴种子中提取的一种特殊氨基酸,在哺乳动物组织中从未发现过,表现出促胰岛素活性;对胰岛素分泌的影响,代谢综合征的植物源性治疗

Packaging

无底玻璃瓶。内含物在插入的融合锥体内。

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

296.6 °F

flash_point_c

147 °C


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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C Broca et al.
European journal of pharmacology, 390(3), 339-345 (2000-03-10)
4-Hydroxyisoleucine, a peculiar amino acid extracted from fenugreek seeds and never found in mammalian tissues, exhibits interesting insulinotropic activity. To investigate the structural requirements for this stimulating effect, the insulinotropic activity of the major isomer (2S,3R,4S) of 4-hydroxyisoleucine, in the
Jasmin Dischinger et al.
PloS one, 4(8), e6788-e6788 (2009-08-27)
Lantibiotics are small microbial peptide antibiotics that are characterized by the presence of the thioether amino acids lanthionine and methyllanthionine. Lantibiotics possess structural genes which encode inactive prepeptides. During maturation, the prepeptide undergoes posttranslational modifications including the introduction of rare
Zhi Zhang et al.
PloS one, 8(4), e62909-e62909 (2013-05-03)
Natural populations of the fruit fly, Drosophila melanogaster, segregate genetic variation that leads to cardiac disease phenotypes. One nearly isogenic line from a North Carolina peach orchard, WE70, is shown to harbor two genetically distinct heart phenotypes: elevated incidence of
Dong Hoon Shin et al.
Annals of laboratory medicine, 34(4), 307-312 (2014-07-02)
Hemolysis, icterus, and lipemia (HIL) cause preanalytical interference and vary unpredictably with different analytical equipments and measurement methods. We developed an integrated reporting system for verifying HIL status in order to identify the extent of interference by HIL on clinical
Anna Maria Herzner et al.
PloS one, 6(7), e22389-e22389 (2011-08-04)
Lantibiotics are small peptide antibiotics that contain the characteristic thioether amino acids lanthionine and methyllanthionine. As ribosomally synthesized peptides, lantibiotics possess biosynthetic gene clusters which contain the structural gene (lanA) as well as the other genes which are involved in

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