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Merck
CN

49767

甘油

greener alternative

BioUltra, Molecular Biology, anhydrous, ≥99.5% (GC)

别名:

1,2,3-丙三醇, 甘油

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关于此项目

线性分子式:
HOCH2CH(OH)CH2OH
化学文摘社编号:
56-81-5
分子量:
92.09
UNSPSC Code:
50161901
NACRES:
NA.25
PubChem Substance ID:
57651220
EC Number:
200-289-5
Beilstein/REAXYS Number:
635685
MDL number:
MFCD00004722
Grade:
Molecular Biology
Assay:
≥99.5% (GC)
Technique(s):
GC/GC: suitable
Bp:
182 °C/20 mmHg (lit.)
Vapor pressure:
<1 mmHg ( 20 °C)

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产品名称

甘油, BioUltra, Molecular Biology, anhydrous, ≥99.5% (GC)

InChI key

PEDCQBHIVMGVHV-UHFFFAOYSA-N

InChI

1S/C3H8O3/c4-1-3(6)2-5/h3-6H,1-2H2

SMILES string

OCC(O)CO

grade

Molecular Biology

vapor density

3.1 (vs air)

vapor pressure

<1 mmHg ( 20 °C)

product line

BioUltra

assay

≥99.5% (GC)

form

viscous liquid

autoignition temp.

698 °F

greener alternative product characteristics

Safer Solvents and Auxiliaries
Design for Degradation
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

technique(s)

GC/GC: suitable

impurities

DNases, none detected
 RNases, none detected
 insoluble matter, passes filter test
 phosphatases, none detected
 proteases, none detected

ign. residue

≤0.1%

refractive index

n20/D 1.474 (lit.)
n20/D 1.474

pH

5.5-8 (25 °C, 5 M in H2O)

bp

182 °C/20 mmHg (lit.)

mp

20 °C (lit.)

solubility

H2O: 5 M at 20 °C, clear, colorless

density

1.25 g/mL (lit.)

anion traces

chloride (Cl-): ≤1 mg/kg
sulfate (SO42-): ≤10 mg/kg

cation traces

Ag: ≤5 mg/kg
Al: ≤1 mg/kg
As: ≤0.1 mg/kg
Ba: ≤1 mg/kg
Bi: ≤1 mg/kg
Ca: ≤5 mg/kg
Cd: ≤1 mg/kg
Co: ≤1 mg/kg
Cr: ≤1 mg/kg
Cu: ≤1 mg/kg
Fe: ≤1 mg/kg
K: ≤20 mg/kg
Li: ≤1 mg/kg
Mg: ≤1 mg/kg
Mn: ≤1 mg/kg
Mo: ≤1 mg/kg
NH4+: ≤5 mg/kg
Na: ≤20 mg/kg
Ni: ≤1 mg/kg
Pb: ≤1 mg/kg
Sr: ≤1 mg/kg
Tl: ≤5 mg/kg
Zn: ≤1 mg/kg

λ

5 M in H2O

UV absorption

λ: 260 nm Amax: 0.05
λ: 280 nm Amax: 0.07

greener alternative category

Aligned

Quality Level

200

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相关类别

Application

甘油被用于聚丙烯酰胺凝胶电泳的样品制备和凝胶形成。甘油（5-10％）可增加样品的密度，使样品在凝胶样品孔的底部分层。甘油还可用于帮助浇注梯度凝胶以及作为蛋白质稳定剂和储存缓冲液的组分。

Biochem/physiol Actions

甘油具有吸湿性，并且因其具有三个亲水性醇羟基而可溶于水。它可以形成分子间和分子内氢键，使其成为一种非常灵活的分子。 甘油的生理作用是由细胞介导的免疫、增加IgG产生和增加组胺释放造成的。
甘油已被用作：
  • 结核分枝杆菌和 鸟分枝杆菌 细胞培养过程中的补充剂。
  • 酶生物燃料电池设计过程的燃料。
  • 在分析中性和酸性聚糖时，与4-HCCA和3-氨基喹啉一起作为液体复合基质。
  • 作为快速原子轰击质谱的基质。
  • 作为MALDI（基质辅助激光解吸/电离质谱）分析定量研究的液体基质。

General description

甘油是无味、无色、粘稠的甜味液体。它可以是天然来源的，也可以来自石化原料。甘油具有广泛的应用，是自然界中最有价值和多功能的化学物质之一。它可用作润肤剂，溶剂，甜味剂以及用于药物配方、化妆品、食品和卫生用品中。它非常稳定，可以在常温下储存；也没有刺激性，对环境无不良影响。
We are committed to bringing you Greener Alternative Products, which adhere to one or more of the 12 Principles of Green Chemistry. Glycerol, with its high boiling point, low flammability, and polarity, is a standout choice. As a non-toxic and biodegradable compound, it aligns perfectly with the principles of ′Safer Solvents and Auxiliaries′ and ′Design for Degradation′. Click here for more information.

Other Notes

核酸(先用乙二醛使其变性）琼脂糖凝胶电泳中上样缓冲液的组分；制备噬菌体和质粒DNA，用于储存纯培养物

存储类别

10 - Combustible liquids

wgk

WGK 1

flash_point_f

390.2 °F - Pensky-Martens closed cup

flash_point_c

199 °C - Pensky-Martens closed cup

ppe

Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCN0165
BCCN0164
BCCN0163
BCCN0162
BCCN0161

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  4. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  5. What is the viscosity of glycerol?

    The viscosity of glycerol is 648 Centistokes at 20 Deg C (68 Deg F).

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R.C. Ogden et al.
Methods in Enzymology, 152, 79-79 (1987)
Practical aspects of preparing phage and plasmid DNA: growth, maintenance, and storage of bacteria and bacteriophage.
H Miller
Methods in enzymology, 152, 145-170 (1987-01-01)
Mohammad S Eram et al.
Biochimica et biophysica acta, 1850(9), 1842-1848 (2015-05-24)
Dysregulation of methylation of lysine 36 on histone H3 (H3K36) have been implicated in a variety of diseases including cancers. ASH1L and SETD2 are two enzymes among others that catalyze H3K36 methylation. H3K4 methylation has also been reported for ASH1L.
Shelley L Forrest et al.
The Journal of comparative neurology, 522(17), 3900-3927 (2014-07-22)
Artemin is a member of the glial cell line-derived neurotrophic factor (GDNF) family that has been strongly implicated in development and regeneration of autonomic nerves and modulation of nociception. Whereas other members of this family (GDNF and neurturin) primarily target
T W Chew et al.
Oncogene, 33(21), 2717-2727 (2013-07-03)
RAS and Rho small GTPases are key molecular switches that control cell dynamics, cell growth and tissue development through their distinct signaling pathways. Although much has been learnt about their individual functions in both cell and animal models, the physiological
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