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Merck
CN

49767

甘油

greener alternative

BioUltra, Molecular Biology, anhydrous, ≥99.5% (GC)

别名:

1,2,3-丙三醇, 甘油

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关于此项目

线性分子式:
HOCH2CH(OH)CH2OH
化学文摘社编号:
分子量:
92.09
UNSPSC Code:
50161901
NACRES:
NA.25
PubChem Substance ID:
EC Number:
200-289-5
Beilstein/REAXYS Number:
635685
MDL number:
Assay:
≥99.5% (GC)
Grade:
Molecular Biology
Technique(s):
GC/GC: suitable
Bp:
182 °C/20 mmHg (lit.)
Vapor pressure:
<1 mmHg ( 20 °C)
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grade

Molecular Biology

Quality Level

vapor density

3.1 (vs air)

vapor pressure

<1 mmHg ( 20 °C)

product line

BioUltra

assay

≥99.5% (GC)

form

viscous liquid

autoignition temp.

698 °F

greener alternative product characteristics

Safer Solvents and Auxiliaries
Design for Degradation
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

technique(s)

GC/GC: suitable

impurities

DNases, none detected, RNases, none detected, insoluble matter, passes filter test, phosphatases, none detected, proteases, none detected

ign. residue

≤0.1%

refractive index

n20/D 1.474

pH

5.5-8 (25 °C, 5 M in H2O)

bp

182 °C/20 mmHg (lit.)

mp

20 °C (lit.)

solubility

H2O: 5 M at 20 °C, clear, colorless

density

1.25 g/mL (lit.)

anion traces

chloride (Cl-): ≤1 mg/kg, sulfate (SO42-): ≤10 mg/kg

SMILES string

OCC(O)CO

cation traces

Ag: ≤5 mg/kg, Al: ≤1 mg/kg, As: ≤0.1 mg/kg, Ba: ≤1 mg/kg, Bi: ≤1 mg/kg, Ca: ≤5 mg/kg, Cd: ≤1 mg/kg, Co: ≤1 mg/kg, Cr: ≤1 mg/kg, Cu: ≤1 mg/kg, Fe: ≤1 mg/kg, K: ≤20 mg/kg, Li: ≤1 mg/kg, Mg: ≤1 mg/kg, Mn: ≤1 mg/kg, Mo: ≤1 mg/kg, NH4+: ≤5 mg/kg, Na: ≤20 mg/kg, Ni: ≤1 mg/kg, Pb: ≤1 mg/kg, Sr: ≤1 mg/kg, Tl: ≤5 mg/kg, Zn: ≤1 mg/kg

λ

5 M in H2O

UV absorption

λ: 260 nm Amax: 0.05, λ: 280 nm Amax: 0.07

greener alternative category

InChI

1S/C3H8O3/c4-1-3(6)2-5/h3-6H,1-2H2

InChI key

PEDCQBHIVMGVHV-UHFFFAOYSA-N

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General description

甘油是无味、无色、粘稠的甜味液体。它可以是天然来源的,也可以来自石化原料。甘油具有广泛的应用,是自然界中最有价值和多功能的化学物质之一。它可用作润肤剂,溶剂,甜味剂以及用于药物配方、化妆品、食品和卫生用品中。它非常稳定,可以在常温下储存;也没有刺激性,对环境无不良影响。
We are committed to bringing you Greener Alternative Products, which adhere to one or more of the 12 Principles of Green Chemistry. Glycerol, with its high boiling point, low flammability, and polarity, is a standout choice. As a non-toxic and biodegradable compound, it aligns perfectly with the principles of ′Safer Solvents and Auxiliaries′ and ′Design for Degradation′. Click here for more information.

Application

甘油被用于聚丙烯酰胺凝胶电泳的样品制备和凝胶形成。甘油(5-10%)可增加样品的密度,使样品在凝胶样品孔的底部分层。甘油还可用于帮助浇注梯度凝胶以及作为蛋白质稳定剂和储存缓冲液的组分。

Biochem/physiol Actions

甘油具有吸湿性,并且因其具有三个亲水性醇羟基而可溶于水。它可以形成分子间和分子内氢键,使其成为一种非常灵活的分子。 甘油的生理作用是由细胞介导的免疫、增加IgG产生和增加组胺释放造成的。
甘油已被用作:
  • 结核分枝杆菌鸟分枝杆菌 细胞培养过程中的补充剂。
  • 酶生物燃料电池设计过程的燃料。
  • 在分析中性和酸性聚糖时,与4-HCCA和3-氨基喹啉一起作为液体复合基质。
  • 作为快速原子轰击质谱的基质。
  • 作为MALDI(基质辅助激光解吸/电离质谱)分析定量研究的液体基质。

Other Notes

核酸(先用乙二醛使其变性)琼脂糖凝胶电泳中上样缓冲液的组分;制备噬菌体和质粒DNA,用于储存纯培养物

存储类别

10 - Combustible liquids

wgk

WGK 1

flash_point_f

390.2 °F - Pensky-Martens closed cup

flash_point_c

199 °C - Pensky-Martens closed cup

ppe

Eyeshields, Gloves


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R.C. Ogden et al.
Methods in Enzymology, 152, 79-79 (1987)
Practical aspects of preparing phage and plasmid DNA: growth, maintenance, and storage of bacteria and bacteriophage.
H Miller
Methods in enzymology, 152, 145-170 (1987-01-01)
Shelley L Forrest et al.
The Journal of comparative neurology, 522(17), 3900-3927 (2014-07-22)
Artemin is a member of the glial cell line-derived neurotrophic factor (GDNF) family that has been strongly implicated in development and regeneration of autonomic nerves and modulation of nociception. Whereas other members of this family (GDNF and neurturin) primarily target
Mohammad S Eram et al.
Biochimica et biophysica acta, 1850(9), 1842-1848 (2015-05-24)
Dysregulation of methylation of lysine 36 on histone H3 (H3K36) have been implicated in a variety of diseases including cancers. ASH1L and SETD2 are two enzymes among others that catalyze H3K36 methylation. H3K4 methylation has also been reported for ASH1L.
Benoît Ranchoux et al.
The American journal of pathology, 185(2), 356-371 (2014-12-17)
Pulmonary veno-occlusive disease (PVOD) is an uncommon form of pulmonary hypertension (PH) characterized by progressive obstruction of small pulmonary veins and a dismal prognosis. Limited case series have reported a possible association between different chemotherapeutic agents and PVOD. We evaluated

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我们提供完整的密度梯度介质产品线,用于分离或提取白细胞、病毒、DNA、RNA、细胞器以及许多其他应用。我们的产品线包括用于在研究实验室中分离白细胞的Histopaque®碘化梯度介质,用于哺乳动物细胞分离的多糖介质,用于哺乳动物细胞和细胞器分离的胶体二氧化硅介质,以及用于DNA、病毒和蛋白质分离的无机盐介质。

全球贸易项目编号

货号GTIN
49767-1L04061832418209
49767-100ML04061832418131
49767-250ML04061832418216

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