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Merck
CN

50649

乙二醛 溶液

BioReagent, ~40% in H2O (~8.8 M), Molecular Biology

别名:

草酸醛, 草醛

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关于此项目

线性分子式:
OHCCHO
化学文摘社编号:
分子量:
58.04
UNSPSC Code:
12352114
NACRES:
NA.52
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1732463
Form:
liquid
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form

liquid

InChI

1S/C2H2O2/c3-1-2-4/h1-2H

SMILES string

[H]C(=O)C([H])=O

InChI key

LEQAOMBKQFMDFZ-UHFFFAOYSA-N

grade

Molecular Biology

product line

BioReagent

concentration

~40% in H2O (~8.8 M)

impurities

DNases, none detected, RNases, none detected, phosphatases, none detected, proteases, none detected

refractive index

n20/D 1.409

anion traces

chloride (Cl-): ≤100 mg/kg, sulfate (SO42-): ≤100 mg/kg

cation traces

Ca: ≤5 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤5 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Na: ≤300 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Zn: ≤5 mg/kg

storage temp.

2-8°C

Quality Level

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General description

乙二醛是一种核酸变性剂。作为 DNA 同源嘌呤链的特异性探针。

Application

适用于
  • 核酸变性
  • DNA/RNA 与硝酸纤维素膜的结合

Biochem/physiol Actions

乙二醛与鸟嘌呤残基形成稳定的复合物,导致核酸变性。

Other Notes

储存过程可能产生沉淀,50-60 °C重新溶解。
这种形式的乙二醛是由 3mol 乙二醛和 2mol 水组成的相对稳定的溶液。

Disclaimer

储存过程可能产生沉淀,50-60℃重新溶解。

pictograms

Health hazardExclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Inhalation - Eye Irrit. 2 - Muta. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

存储类别

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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R N Skopp et al.
Analytical biochemistry, 169(1), 132-137 (1988-02-15)
This paper describes agarose gel electrophoresis and silver staining of denatured RNAs. Glyoxal- or formaldehyde-denatured RNAs are electrophoresed in an agarose gel cast on a plastic support using an inert, low conductivity buffer. Following electrophoresis, the gel is stained with
Hybridization of denatured RNA transferred or dotted nitrocellulose paper.
P S Thomas
Methods in enzymology, 100, 255-266 (1983-01-01)
M Vojtisková et al.
Journal of biomolecular structure & dynamics, 5(2), 283-296 (1987-10-01)
Plasmid pEJ4, which is a derivative of pUC19 containing an insert with 60-bp-long homopurine.homopyrimidine tract from sea urchin P. miliaris histone gene spacer, was studied by chemical probes of the DNA structure osmium tetroxide and glyoxal. The former probe reacts
Prasanna Channathodiyil et al.
PloS one, 16(1), e0240769-e0240769 (2021-01-23)
A simple method for extraction of high quality RNA from cells that have been fixed, stained and sorted by flow cytometry would allow routine transcriptome analysis of highly purified cell populations and single cells. However, formaldehyde fixation impairs RNA extraction
Catherine Lambert et al.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 18(1), 59-69 (2012-10-30)
The molecular basis of Alzheimer's disease has not been clearly established, but disruption of brain metal ion homeostasis, particularly copper and zinc, might be closely involved in the pathogenesis of this disease and its characteristic β-amyloid neuropathological features. The use

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