51120
5′-三磷酸鸟苷 钠盐 水合物
≥90% (HPLC), powder
别名:
GTP-Na⁺ 水合物, 5′-GTP-Na2
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C10H16N5O14P3 · xNa+ · yH2O
化学文摘社编号:
分子量:
523.18 (anhydrous free acid basis)
NACRES:
NA.51
PubChem Substance ID:
UNSPSC Code:
41106305
EC Number:
252-847-2
MDL number:
Beilstein/REAXYS Number:
4113439
产品名称
5′-三磷酸鸟苷 钠盐 水合物, ≥90% (HPLC)
InChI key
HPLNHYUZFVUXFJ-ZVQJTLEUSA-L
InChI
1S/C10H16N5O14P3.2Na.2H2O/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21;;;;/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H,24,25)(H2,19,20,21)(H3,11,13,14,18);;;2*1H2/q;2*+1;;/p-2/t3-,5-,6-,9-;;;;/m1..../s1
SMILES string
O.O.[Na+].[Na+].NC1=Nc2c(ncn2[C@@H]3O[C@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]3O)C(=O)N1
assay
≥90% (HPLC)
form
powder
optical activity
[α]20/D −24±2°, c = 1% in 0.5 M Na2HPO4
impurities
≤3 mol/mol water (NMR)
solubility
water: 50 mg/mL, clear, colorless
shipped in
wet ice
storage temp.
−20°C
Quality Level
正在寻找类似产品? 访问 产品对比指南
Application
鸟苷 5′-三磷酸钠盐水合物已用于：
- 作为星形胶质细胞膜片钳内液的组成部分，监测小鼠杏仁核切片星形胶质细胞的钙活性。
- 利用电压钳技术记录细胞系中通道电流的溶液。
- 制备内部记录注射溶液，用于将基因传递到机械感觉毛细胞。
- 在通过体积排除色谱法（SEC）分析齐聚反应过程中，促进G界面介导的人septin蛋白同源二聚体的形成。
General description
5′-三磷酸鸟苷(GTP)是一种嘌呤三核苷酸磷酸。GTP是各种G-蛋白偶联受体(GPCR)GTP酶及细胞信号转导和GTP/GDP循环相关鸟嘌呤核苷酸交换因子(GEF)的底物。如需进行RNA聚合酶转录、DNA/RNA生物合成，请访问G3776产品。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type N95 (US)
Lukas Jakob Neukomm et al.
Development (Cambridge, England), 138(10), 2003-2014 (2011-04-15)
Multicellular organisms use programmed cell death to eliminate unwanted or potentially harmful cells. Improper cell corpse removal can lead to autoimmune diseases. The development of interventional therapies that increase engulfment activity could represent an attractive approach to treat such diseases.
Gyu-Sang Hong et al.
Neuron, 94(2), 271-273 (2017-04-21)
Mechanosensation is essential for various physiological processes, and it is mediated by mechanotransduction channels. Recently, we reported that TMEM150C/Tentonin 3 (TTN3) confers mechanically activated currents with slow inactivation kinetics in several cell types, including dorsal root ganglion neurons (Hong et al.
Hiroaki Kajiho et al.
The Journal of biological chemistry, 286(27), 24364-24373 (2011-05-19)
The small GTPase Rab5, which cycles between GDP-bound inactive and GTP-bound active forms, plays essential roles in membrane budding and trafficking in the early endocytic pathway. Rab5 is activated by various vacuolar protein sorting 9 (VPS9) domain-containing guanine nucleotide exchange
Angel Baudon et al.
STAR protocols, 3(1), 101159-101159 (2022-02-25)
Astrocytes are glial cells that exhibit calcium signaling-mediated activity. Here, we present a protocol to monitor and manipulate astrocyte calcium activity from mouse amygdala slices. In the first part of this protocol, we describe the procedure of astrocyte calcium imaging.
M Uriarte et al.
The Biochemical journal, 293 ( Pt 1), 93-100 (1993-07-01)
A glycoprotein fraction was isolated from rat liver membranes by affinity chromatography on immobilized wheat-germ lectin. Incubation of this fraction with MgATP or MgGTP resulted in a sequential phosphorylation and dephosphorylation of a complex of three polypeptides (118, 128 and
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持