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51280

氯化高铁血红素

Name: 氯化高铁血红素
Brand: SIGMA

BioXtra, from Porcine, ≥96.0% (HPLC)

别名:

氯(原卟啉酸)铁(III), 氯化血红素, 氯原卟啉IX铁(III), 高铁原卟啉IX氯, 高铁血红素（氯）

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关于此项目

经验公式（希尔记法）:

C₃₄H₃₂ClFeN₄O₄

化学文摘社编号:

16009-13-5

分子量:

651.94

UNSPSC Code:

12352202

NACRES:

NA.79

PubChem Substance ID:

57651319

EC Number:

240-140-1

Beilstein/REAXYS Number:

5229914

MDL number:

MFCD00010726

Form:

powder or crystals

Assay:

≥96.0% (HPLC)

Biological source:

Porcine

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biological source

Porcine

Quality Level

200

product line

BioXtra

assay

≥96.0% (HPLC)

form

powder or crystals

technique(s)

tissue culture: suitable, transfection: suitable

storage temp.

2-8°C

SMILES string

Cc1c(CCC(O)=O)c2cc3c(CCC(O)=O)c(C)c4cc5nc(cc6c(C)c(C=C)c(cc1n2)n6[Fe](Cl)n34)c(C=C)c5C

InChI

1S/C34H34N4O4.ClH.Fe/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25;;/h7-8,13-16H,1-2,9-12H2,3-6H3,(H4,35,36,37,38,39,40,41,42);1H;/q;;+3/p-3/b25-13-,26-13-,27-14-,28-15-,29-14-,30-15-,31-16-,32-16-;;

InChI key

BTIJJDXEELBZFS-HXFTUNQESA-K

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Application

高铁血红素应用于以下应用中：

研究菌株和生长条件
用于短期菌落测定(培养基由血红素和其他成分组成)
细胞转染

它可用于分析MMV(抗疟药物)疟疾盒化合物对β-血红蛋白形成的抑制作用。

Biochem/physiol Actions

高铁血红素是经氧化血红素，是一系列蛋白质的一种含铁的辅基基团。游离血红素在溶血后从血红蛋白中释放出来，具有促炎作用，有助于铁源活性氧的生成。游离血红素水平可在各种病理条件下上调，并可导致各种炎症条件，包括血管疾病、肾功能衰竭和免疫介导的疾病。

高铁血红素可用于研究血红素加氧酶1 (HO-1)的表达和抑制以及HO-1的活性。血凝素是生长流感嗜血杆菌所必需的“X因子”。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

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