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Merck
CN

53604

Sigma-Aldrich

Nε-三氟乙酰基-L-赖氨酸

≥96.0% (TLC)

别名:

ε-TFA-赖氨酸

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关于此项目

经验公式(希尔记法):
C8H13F3N2O3
化学文摘社编号:
分子量:
242.20
Beilstein:
2122429
MDL编号:
UNSPSC代码:
12352209
PubChem化学物质编号:
NACRES:
NA.26
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方案

≥96.0% (TLC)

表单

powder

杂质

≤7% water

颜色

white to off-white

mp

>215 °C

溶解性

2 M HCl: 10 mg/mL, clear, colorless

应用

peptide synthesis

储存温度

2-8°C

SMILES字符串

N[C@@H](CCCCNC(=O)C(F)(F)F)C(O)=O

InChI

1S/C8H13F3N2O3/c9-8(10,11)7(16)13-4-2-1-3-5(12)6(14)15/h5H,1-4,12H2,(H,13,16)(H,14,15)/t5-/m0/s1

InChI key

PZZHRSVBHRVIMI-YFKPBYRVSA-N

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生化/生理作用

Nε-三氟乙酰基-L-赖氨酸可被用于生成能够用于非水性毛细管电泳(NACE)的合成有机多肽。
Nε-三氟乙酰基-L-赖氨酸是L-赖氨酸环脱氨酶的一种抑制剂。

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Hervé Cottet et al.
Analytical chemistry, 75(20), 5554-5560 (2004-01-09)
Poly(Nepsilon-trifluoroacetyl-L-lysine) was used as a model solute to investigate the potential of nonaqueous capillary electrophoresis (NACE) for the characterization of synthetic organic polymers. The information obtained by NACE was compared to that derived from size exclusion chromatography (SEC) experiments, and
Min He et al.
Gene, 377, 109-118 (2006-06-30)
Meridamycin is a non-immunosuppressive, FKBP12-binding natural macrolide with potential therapeutic applications in a variety of medical conditions. To set the stage for structural modification of meridamycin by genetic engineering, we have cloned and completely sequenced approximately 117 kb of DNA
Determination of synthetic polypeptide conformations and molecular geometrical parameters by nonaqueous CE.
Plasson R, Vayaboury W, Giani O, Cottet H.
Electroanalysis, 28, 3617-3624 (2007)
Georgia Eleni Tsotsou et al.
Biochimie, 89(5), 591-604 (2007-02-13)
L-Lysine cyclodeaminase from Streptomyces pristinaespiralis was heterologously expressed in Escherichia coli, isolated to 90% purity after two purification steps and characterised. The size of the isolated recombinant enzyme was in agreement with the theoretical size calculated from the corresponding gene.
Gerhard K E Scriba
Journal of chromatography. A, 1159(1-2), 28-41 (2007-02-24)
Nonaqueous background electrolytes broaden the application of capillary electrophoresis displaying altered separation selectivity and interactions between analytes and buffer additives compared to aqueous background electrolytes. In addition, nonaqueous capillary electrophoresis (NACE) appears to be ideally suited for online coupling with

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