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53751

海胺^® 1622

Name: 海胺<SUP>®</SUP> 1622
Brand: SIGMA

BioUltra, ≥99.0% (AT)

别名:

苄索氯铵, 氯化苄乙氧铵, （二异丁基苯氧基乙氧基乙基）二甲基苄基氯化铵溶液

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关于此项目

经验公式（希尔记法）:

C₂₇H₄₂ClNO₂

化学文摘社编号:

121-54-0

分子量:

448.08

UNSPSC Code:

12161900

NACRES:

NA.25

PubChem Substance ID:

57651440

EC Number:

204-479-9

Beilstein/REAXYS Number:

3898548

MDL number:

MFCD00011742

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Quality Level

100

description

cationic

product line

BioUltra

assay

≥99.0% (AT)

form

(Powder, Colorless or White)

mol wt

448.08 g/mol

impurities

insoluble matter, passes filter test, ≤5% water

pH

5.5-7.5 (25 °C, 0.1 M in H₂O)

mp

162-164 °C (lit.)

solubility

H₂O: 0.1 M at 20 °C, clear, colorless

anion traces

sulfate (SO₄^2-): ≤50 mg/kg

cation traces

Al: ≤5 mg/kg, Ba: ≤5 mg/kg, Bi: ≤5 mg/kg, Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤50 mg/kg, Li: ≤5 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Mo: ≤5 mg/kg, Na: ≤50 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Sr: ≤5 mg/kg, Zn: ≤5 mg/kg

absorption

cut-off at 300 nm in H₂O at 0.1 M

application(s)

(Pharmaceuticals/personal care)
(Pharmaceuticals/personal care)

SMILES string

[Cl-].CC(C)(C)CC(C)(C)c1ccc(OCCOCC[N+](C)(C)Cc2ccccc2)cc1

InChI

1S/C27H42NO2.ClH/c1-26(2,3)22-27(4,5)24-13-15-25(16-14-24)30-20-19-29-18-17-28(6,7)21-23-11-9-8-10-12-23;/h8-16H,17-22H2,1-7H3;1H/q+1;/p-1

InChI key

UREZNYTWGJKWBI-UHFFFAOYSA-M

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General description

苄索氯铵是一种良好表征的皮肤刺激剂和罕见致敏剂。

Application

苄索氯铵用于一项评估马来西亚耐甲氧西林金黄色葡萄球菌 (MRSA) 分离株的最低抑菌浓度的研究。它也被用于从海藻酸钠和改性粘土制备生物复合膜的研究。

Disclaimer

根据全球生物杀灭剂的法规，包括但不限于美国环境保护局的《联邦杀虫剂、杀真菌剂和灭鼠剂法案》、《欧洲生物杀灭剂法规》、加拿大害虫管理局、土耳其《生物杀灭剂产品法规》、韩国《消费化学产品和生物杀灭剂安全管理法案》(K-BPR)，该产品不可用作生物杀灭剂。

pictograms

GHS06,GHS05,GHS09

signalword

Danger

hcodes

H301,H314,H410

pcodes

P260 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1B

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 2

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

0000477262

0000424013

0000424033

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Neomycin-phenolic conjugates: polycationic amphiphiles with broad-spectrum antibacterial activity, low hemolytic activity and weak serum protein binding.

Brandon Findlay et al.

Bioorganic & medicinal chemistry letters, 22(4), 1499-1503 (2012-01-31)

Here we present a proof-of-concept study, combining two known antimicrobial agents into a hybrid structure in order to develop an emergent cationic detergent-like interaction with the bacterial membrane. Six amphiphilic conjugates were prepared by copper (I)-catalyzed 1,3-dipolar cycloaddition between a

Stimulation of suicidal erythrocyte death by benzethonium.

Elisabeth Lang et al.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 28(2), 347-354 (2011-08-26)

Benzethonium, an antimicrobial surfactant widely used as preservative of pharmaceuticals, topical wound care product and oral disinfectant, triggers apoptosis of several cell types. The apoptosis is preceded and possibly triggered by mitochondrial depolarization. Even though lacking mitochondria, erythrocytes may similarly

Convergent synthesis of fluorescence-labeled probes of Annonaceous acetogenins and visualization of their cell distribution.

Naoto Kojima et al.

Bioorganic & medicinal chemistry, 18(24), 8630-8641 (2010-11-16)

The convergent synthesis of fluorescence-labeled solamin, an antitumor Annonaceous acetogenin, was accomplished by two asymmetric alkynylations of 2,5-diformyl tetrahydrofuran with an alkyne tagged with fluorescent groups and another alkyne with an α,β-unsaturated γ-lactone. Assay for the growth inhibitory activity against

The enhancement effect of three sugar alcohols on the fungicidal effect of benzethonium chloride toward Candida albicans.

T Ichikawa et al.

Journal of dentistry, 36(11), 965-968 (2008-09-10)

The purpose of this study was to evaluate if the sugar alcohols erythritol, xylitol and sorbitol enhance the fungicidal effect of benzethonium chloride (BTC) toward in vitro candidal biofilms. An in vitroCandida albicans biofilm was formed on a plastic coverslip

Ototoxicity of aluminum acetate/benzethonium chloride otic solution in the chinchilla animal model.

Jacob Pitaro et al.

The Laryngoscope, 123(10), 2521-2525 (2013-08-07)

To determine the ototoxic potential of aluminum acetate (0.5%)/benzethonium chloride (0.03%) otic solution in the chinchilla animal model. A randomized, prospective, controlled study was conducted in the chinchilla animal model. Fourteen female chinchillas were used. After an incision was made

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全球贸易项目编号

货号	GTIN
15200-50ML	04061838740083
53751-50G	04061835541508
53751-250G	04061835541492

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