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Merck
CN

54880

3-羟基苄肼 二盐酸盐

≥98.0% (HPLC)

别名:

α-肼基-间-甲酚 二盐酸盐, 3-(肼基甲基)苯酚 二盐酸盐, NSD-1015

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关于此项目

线性分子式:
HOC6H4CH2NHNH2 · 2HCl
化学文摘社编号:
81012-99-9
分子量:
211.09
Beilstein:
9282965
EC 号:
279-659-3
MDL编号:
MFCD00044695
UNSPSC代码:
12352202
PubChem化学物质编号:
24878937
NACRES:
NA.77

主要文件

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质量水平

100

方案

≥98.0% (HPLC)

表单

solid

mp

137-140 °C
138-140 °C (lit.)

溶解性

H2O: 50 mg/mL, slightly hazy, faintly yellow

SMILES字符串

Cl[H].Cl[H].NNCc1cccc(O)c1

InChI

1S/C7H10N2O.2ClH/c8-9-5-6-2-1-3-7(10)4-6;;/h1-4,9-10H,5,8H2;2*1H

InChI key

ONOJPUDFIOEGCX-UHFFFAOYSA-N

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相关类别

生化/生理作用

L-芳香族氨基酸脱羧酶抑制剂；穿过血脑屏障。
L-芳香族氨基酸脱羧酶抑制剂；穿过血脑屏障。还可通过形成该辅因子的3-羟基苄基腙，还抑制GABA转氨酶以及其他需要磷酸吡哆醛的酶。

象形图

CorrosionExclamation mark
GHS05,GHS07

警示用语：

Danger

危险分类

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCBT7147
BCBG5065V
BCBB1136V
BCBB1136
1445429

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血清素合成及代谢

血清素（5-羟色胺）主要存在于三种主要细胞类型中：i）中杻神经系统（CNS）和肠肌间神经丛中的血清素能神经元，ii）胃肠道粘膜中的肠嗜铬细胞，和iii）血小板。血清素的代谢主要通过外部线粒体膜酶单胺氧化酶（MAO）进行，它以两种分子亚型存在，分别称为MAO-A和MAO-B。

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