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Merck
CN

56189

羟苯基丙酸 N-羟基琥珀酰亚胺酯

≥97.0% (C), BioReagent

别名:

N-[(4-羟基氢化肉桂酰基)氧基]琥珀酰亚胺, N-琥珀酰亚胺 3-(4-羟基苯基)丙酸酯, Bolton-Hunter 试剂前体, Rudinger 试剂, SHPP

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关于此项目

经验公式(希尔记法):
C13H13NO5
化学文摘社编号:
分子量:
263.25
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352106
EC Number:
251-818-1
MDL number:
Beilstein/REAXYS Number:
1545011
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产品名称

羟苯基丙酸 N-羟基琥珀酰亚胺酯, BioReagent, suitable for fluorescence, ≥97% (C)

InChI key

KYRUKRFVOACELK-UHFFFAOYSA-N

InChI

1S/C13H13NO5/c15-10-4-1-9(2-5-10)3-8-13(18)19-14-11(16)6-7-12(14)17/h1-2,4-5,15H,3,6-8H2

SMILES string

Oc1ccc(CCC(=O)ON2C(=O)CCC2=O)cc1

product line

BioReagent

mp

132-133 °C (lit.)

fluorescence

λex 320 nm; λem 409 nm in 0.1 M Tris pH 8.8, 2 mM H2O2, peroxidase

suitability

suitable for fluorescence

storage temp.

−20°C

Quality Level

assay

≥97% (C)

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Application

Bolton-Hunter reagent precursor (3-(4-Hydroxyphenyl)propionic acid N-hydroxysuccinimide ester) is a hydroxysuccinimide ester used as an intermediate for high radioactive radioiodination of proteins.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Appendix: Preparation of N-succinimidyl 3-(4-hydroxyphenyl)propionate.
J Rudinger et al.
The Biochemical journal, 133(3), 538-539 (1973-07-01)
Jae Jun Park et al.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 69(1), 56-62 (2010-10-05)
In this study, the radioiodination and biodistribution of quantum dots (QDs) using Bolton-Hunter reagent were investigated. Radioiodination yield was 33.4 ± 2.0%. Fluorescent intensity of radioiodinated QDs decreased to 75.4% of the maximum prior to radioiodination. In biodistribution and ex
Labeling of peptides and proteins by radioiodination.
Bailey GS.
Methods Mol. Cell Biol., 32, 441-448 (1994)
Radioiodination of cellular proteins.
Caplan S, Baniyash M.
Current Protocols in Cell Biology, 7, 7-7 (2001)
D P McManus et al.
Journal of helminthology, 61(1), 47-52 (1987-03-01)
Living, intact protoscoleces of the British horse and sheep strains of Echinococcus granulosus were subjected to surface radioiodination procedures using 125I and Iodogen and 125I-Bolton Hunter reagent. Subsequent combined electron microscopy and autoradiography revealed specific surface membrane labelling with the

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