56189
羟苯基丙酸 N-羟基琥珀酰亚胺酯
≥97.0% (C), BioReagent
别名:
N-[(4-羟基氢化肉桂酰基)氧基]琥珀酰亚胺, N-琥珀酰亚胺 3-(4-羟基苯基)丙酸酯, Bolton-Hunter 试剂前体, Rudinger 试剂, SHPP
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关于此项目
经验公式（希尔记法）:
C13H13NO5
化学文摘社编号:
分子量:
263.25
Beilstein:
1545011
EC 号:
MDL编号:
UNSPSC代码:
12352106
PubChem化学物质编号:
NACRES:
NA.25
产品名称
羟苯基丙酸 N-羟基琥珀酰亚胺酯, BioReagent, suitable for fluorescence, ≥97% (C)
产品线
BioReagent
方案
≥97% (C)
mp
132-133 °C (lit.)
荧光
λex 320 nm; λem 409 nm in 0.1 M Tris pH 8.8, 2 mM H2O2, peroxidase
适用性
suitable for fluorescence
储存温度
−20°C
SMILES字符串
Oc1ccc(CCC(=O)ON2C(=O)CCC2=O)cc1
InChI
1S/C13H13NO5/c15-10-4-1-9(2-5-10)3-8-13(18)19-14-11(16)6-7-12(14)17/h1-2,4-5,15H,3,6-8H2
InChI key
KYRUKRFVOACELK-UHFFFAOYSA-N
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应用
Bolton-Hunter reagent precursor (3-(4-Hydroxyphenyl)propionic acid N-hydroxysuccinimide ester) is a hydroxysuccinimide ester used as an intermediate for high radioactive radioiodination of proteins.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Appendix: Preparation of N-succinimidyl 3-(4-hydroxyphenyl)propionate.
J Rudinger et al.
The Biochemical journal, 133(3), 538-539 (1973-07-01)
Jae Jun Park et al.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 69(1), 56-62 (2010-10-05)
In this study, the radioiodination and biodistribution of quantum dots (QDs) using Bolton-Hunter reagent were investigated. Radioiodination yield was 33.4 ± 2.0%. Fluorescent intensity of radioiodinated QDs decreased to 75.4% of the maximum prior to radioiodination. In biodistribution and ex
D P McManus et al.
Journal of helminthology, 61(1), 47-52 (1987-03-01)
Living, intact protoscoleces of the British horse and sheep strains of Echinococcus granulosus were subjected to surface radioiodination procedures using 125I and Iodogen and 125I-Bolton Hunter reagent. Subsequent combined electron microscopy and autoradiography revealed specific surface membrane labelling with the
P Portolés et al.
Journal of immunological methods, 129(1), 105-109 (1990-05-08)
A method for the vectorial radioiodination of CD4 and other membrane proteins having few or no tyrosine residues in the extracytoplasmic domains is described. Incubation of the cells with sulfosuccinimidyl (hydroxyphenyl) propionate (sulfo-SHPP), a water-soluble derivative of the Bolton-Hunter reagent
E Marshall et al.
Molecular and biochemical parasitology, 15(3), 295-304 (1985-06-01)
The specificity of a range of 125I labelling techniques (Chloramine T, Iodogen, Bolton and Hunter reagent, lactoperoxidase and iodosulfanilic acid) to the surface of the filarial nematode Brugia pahangi was evaluated by autoradiography of sections of labelled worms and of
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