56189
羟苯基丙酸 N-羟基琥珀酰亚胺酯
≥97.0% (C), BioReagent
别名:
N-[(4-羟基氢化肉桂酰基)氧基]琥珀酰亚胺, N-琥珀酰亚胺 3-(4-羟基苯基)丙酸酯, Bolton-Hunter 试剂前体, Rudinger 试剂, SHPP
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关于此项目
经验公式（希尔记法）:
C13H13NO5
化学文摘社编号:
分子量:
263.25
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352106
EC Number:
251-818-1
MDL number:
Beilstein/REAXYS Number:
1545011
产品名称
羟苯基丙酸 N-羟基琥珀酰亚胺酯, BioReagent, suitable for fluorescence, ≥97% (C)
InChI key
KYRUKRFVOACELK-UHFFFAOYSA-N
InChI
1S/C13H13NO5/c15-10-4-1-9(2-5-10)3-8-13(18)19-14-11(16)6-7-12(14)17/h1-2,4-5,15H,3,6-8H2
SMILES string
Oc1ccc(CCC(=O)ON2C(=O)CCC2=O)cc1
product line
BioReagent
mp
132-133 °C (lit.)
fluorescence
λex 320 nm; λem 409 nm in 0.1 M Tris pH 8.8, 2 mM H2O2, peroxidase
suitability
suitable for fluorescence
storage temp.
−20°C
Quality Level
assay
≥97% (C)
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Application
Bolton-Hunter reagent precursor (3-(4-Hydroxyphenyl)propionic acid N-hydroxysuccinimide ester) is a hydroxysuccinimide ester used as an intermediate for high radioactive radioiodination of proteins.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Jae Jun Park et al.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 69(1), 56-62 (2010-10-05)
In this study, the radioiodination and biodistribution of quantum dots (QDs) using Bolton-Hunter reagent were investigated. Radioiodination yield was 33.4 ± 2.0%. Fluorescent intensity of radioiodinated QDs decreased to 75.4% of the maximum prior to radioiodination. In biodistribution and ex
D P McManus et al.
Journal of helminthology, 61(1), 47-52 (1987-03-01)
Living, intact protoscoleces of the British horse and sheep strains of Echinococcus granulosus were subjected to surface radioiodination procedures using 125I and Iodogen and 125I-Bolton Hunter reagent. Subsequent combined electron microscopy and autoradiography revealed specific surface membrane labelling with the
Labeling of peptides and proteins by radioiodination.
Bailey GS.
Methods Mol. Cell Biol., 32, 441-448 (1994)
Appendix: Preparation of N-succinimidyl 3-(4-hydroxyphenyl)propionate.
J Rudinger et al.
The Biochemical journal, 133(3), 538-539 (1973-07-01)
M Rack et al.
Pflugers Archiv : European journal of physiology, 400(4), 403-408 (1984-04-01)
Several reagents that react with sulfhydryl and amino groups were applied to voltage-clamped single nerve fibres of the frog. The fibres were exposed to comparable amounts of the chemical reagents for relatively short times. 3-(p-Hydroxyphenyl)propionic acid N-hydroxysuccinimide ester (HPPS), a
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