Merck
CN

56395

Sigma-Aldrich

N-己酰基-L-高丝氨酸内酯

≥96% (HPLC)

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别名:
N-[(3S)-四氢-2-氧代-3-呋喃基]己酰胺, N-己酰基-L-高丝氨酸内酯, C6-HSL, HHL
Empirical Formula (Hill Notation):
C10H17NO3
分子量:
199.25
Beilstein:
8143287
MDL编号:
PubChem化学物质编号:

质量水平

检测方案

≥96% (HPLC)

形式

powder or crystals

旋光性

[α]/D -32±3°, c = 0.2 in methanol

颜色

white to off-white

适用性

conforms to structure for Proton NMR spectrum

储存温度

−20°C

SMILES string

O=C1OCC[C@@H]1NC(CCCCC)=O

InChI

1S/C10H17NO3/c1-2-3-4-5-9(12)11-8-6-7-14-10(8)13/h8H,2-7H2,1H3,(H,11,12)/t8-/m0/s1

InChI key

ZJFKKPDLNLCPNP-QMMMGPOBSA-N

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O90145108644558
form

powder or crystals

form

powder

form

powder or crystals

form

powder or crystals

optical activity

[α]/D -32±3°, c = 0.2 in methanol

optical activity

-

optical activity

[α]/D -29±3°, c = 0.2 in methanol

optical activity

[α]/D -28±3°, c = 0.2 in methanol

color

white to off-white

color

white

color

white

color

white to off-white

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

suitability

conforms to structure for Proton NMR spectrum

suitability

-

suitability

conforms to structure for Proton NMR spectrum

suitability

conforms to structure for Proton NMR spectrum

生化/生理作用

N-己酰基-L-高丝氨酸内酯是N-酰基-高丝氨酸内酯家族的成员。N-酰基高丝氨酸内酯(AHL)可调控革兰氏阴性细菌(如埃希氏菌沙门氏菌)的基因表达,参与群体感应、细菌的细胞间通讯;评论见。细菌的细胞间通讯成为新型抗毒力药物开发的靶标和预防生物膜形成的研究热点
群体感应信号发生

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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S Torabi Delshad et al.
Journal of applied microbiology, 125(2), 356-369 (2018-04-26)
A variety of pathogens use quorum sensing (QS) to control the expression of their virulence factors. QS interference has hence been proposed as a promising antivirulence strategy. The specific aim of this study was to isolate bacteria from trout tissue
Orrapun Selamassakul et al.
Journal of food science, 85(3), 707-717 (2020-02-12)
This study evaluated the biological properties of peptides from brown rice protein hydrolyzed by bromelain (eb-RPH) in relation to flavor characteristic. The fractionation into peptides < 1 kDa was observed to improve the DPPH, ABTS, and hydroxyl radical-scavenging activities (0.19, 2.28, and
Chi-I Chang et al.
Molecules (Basel, Switzerland), 24(11) (2019-06-13)
Three new dimeric abietane-type diterpenoids, abieta-6,8,11,13-tetraen-12-yl 12-hydroxyabieta-8,11,13-trien-7α-yl peroxide (1), abieta-6,8,11,13-tetraen-12-yl 12-hydroxyabieta-8,11,13-trien-7β-yl peroxide (2), and 12-hydroxyabieta-8,11,13-trien-7β-yl 7-oxoabieta-5,8,11,13-tetraen-12-yl peroxide (3), together with four known abietane-type diterpenoids (4-7) were isolated from the methanol extract of the bark of Cryptomeria japonica. Their structures were
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Biochemistry, 48(20), 4344-4353 (2009-04-21)
The PLL(PTE-like lactonase)-group of enzymes within the amidohydrolase superfamily hydrolyze N-acyl-homoserine lactones (AHLs) that are involved in bacterial quorum-sensing pathways. These enzymes possess the (beta/alpha)(8)-barrel fold and serve as attractive templates for in vitro evolution and engineering of quorum-quenching biological
Xue Yang et al.
Ultrasonics sonochemistry, 38, 19-28 (2017-06-22)
The effects of ultrasound pretreatment with different frequencies and working modes, including mono-frequency ultrasound (MFU), dual-frequency ultrasound (DFU) and tri-frequency ultrasound (TFU), on the degree of hydrolysis (DH) of rice protein (RP) and angiotensin-I-converting enzyme (ACE) inhibitory activity of RP

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