57600
IL-2 human
≥98% (GE), recombinant, expressed in E. coli, liquid
别名:
IL-2, TCGF, hIL-2
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关于此项目
Biological source:
human
Recombinant:
expressed in E. coli
Form:
liquid
Mol wt:
Mr ~15500
产品名称
白细胞介素-2 人, recombinant, expressed in E. coli, ~10000 U/mL
biological source
human
recombinant
expressed in E. coli
form
liquid
mol wt
Mr ~15500
packaging
vial of 1 mL
concentration
~10000 U/mL
color
colorless
UniProt accession no.
shipped in
dry ice
storage temp.
−70°C
Quality Level
Gene Information
human ... IL2(3558)
Biochem/physiol Actions
促进IL-2依赖性淋巴细胞的生长。 IL-2的氨基酸序列。
Disclaimer
在−20 °C下稳定；准备合适的分装品，避免反复冻融，否则可能会发生聚集，导致活性明显下降。
Other Notes
1个单位对应于CTLL-2细胞的比色MTT分析中的单位活性。
可能适用相应的销售限制。
Packaging
一瓶含10′000单位
Physical form
透明无色的溶液，溶剂为Dulbecco-PBS；含1 mg BSA/mL。
存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
低风险生物材料
此项目有
S Gillis et al.
Journal of immunology (Baltimore, Md. : 1950), 120(6), 2027-2032 (1978-06-01)
Several soluble factors have recently been associated with the proliferation and differentiation of thymus-derived lymphocytes. One of these factors present in medium conditioned by T cell mitogen-stimulated lymphocytes has the ability to promote the long-term culture of normal and antigen-specific
Interleukin 2.
K A Smith
Annual review of immunology, 2, 319-333 (1984-01-01)
R J Robb et al.
Proceedings of the National Academy of Sciences of the United States of America, 81(20), 6486-6490 (1984-10-01)
Human interleukin 2 was separated into multiple molecular forms by selective immunoaffinity chromatography and chromatofocusing. For the most part, this heterogeneity was attributed to variations in glycosylation of the threonine residue in position 3 of the polypeptide chain. The various
Denise L Cecil et al.
Cancer research, 74(10), 2710-2718 (2014-04-30)
Immunization against self-tumor antigens can induce T-regulatory cells, which inhibit proliferation of type I CD4(+) T-helper (TH1) and CD8(+) cytotoxic T cells. Type I T cells are required for potent antitumor immunity. We questioned whether immunosuppressive epitopes could be identified
Cecilie Brekke Rygh et al.
PloS one, 9(9), e108414-e108414 (2014-10-01)
There are currently no established radiological parameters that predict response to immunotherapy. We hypothesised that multiparametric, longitudinal magnetic resonance imaging (MRI) of physiological parameters and pharmacokinetic models might detect early biological responses to immunotherapy for glioblastoma targeting NG2/CSPG4 with mAb9.2.27
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