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Merck
CN
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文件

安全信息

57600

Sigma-Aldrich

白细胞介素-2 人

recombinant, expressed in E. coli, ~10000 U/mL

别名:

IL-2, TCGF, hIL-2

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About This Item

CAS号:
MDL编号:
UNSPSC代码:
12352202
NACRES:
NA.32

生物来源

human

质量水平

重组

expressed in E. coli

形式

liquid

分子量

Mr ~15500

包装

vial of 1 mL

浓度

~10000 U/mL

颜色

colorless

UniProt登记号

运输

dry ice

储存温度

−70°C

基因信息

human ... IL2(3558)

生化/生理作用

促进IL-2依赖性淋巴细胞的生长。 IL-2的氨基酸序列。

包装

一瓶含10′000单位

注意

在−20 °C下稳定;准备合适的分装品,避免反复冻融,否则可能会发生聚集,导致活性明显下降。

单位定义

1个单位对应于CTLL-2细胞的比色MTT分析中的单位活性。

外形

透明无色的溶液,溶剂为Dulbecco-PBS;含1 mg BSA/mL。

其他说明

可能适用相应的销售限制。

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

常规特殊物品
含少量动物源组分生物产品

分析证书(COA)

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Interleukin 2.
K A Smith
Annual review of immunology, 2, 319-333 (1984-01-01)
S Gillis et al.
Journal of immunology (Baltimore, Md. : 1950), 120(6), 2027-2032 (1978-06-01)
Several soluble factors have recently been associated with the proliferation and differentiation of thymus-derived lymphocytes. One of these factors present in medium conditioned by T cell mitogen-stimulated lymphocytes has the ability to promote the long-term culture of normal and antigen-specific
Sagar Darvekar et al.
Cancers, 12(2) (2020-02-12)
Extracorporeal photopheresis (ECP), a modality that exposes isolated leukocytes to the photosensitizer 8-methoxypsoralen (8-MOP) and ultraviolet-A (UV-A) light, is used to treat conditions such as cutaneous T-cell lymphoma and graft-versus-host disease. However, the current procedure of ECP has limited selectivity
Cecilie Brekke Rygh et al.
PloS one, 9(9), e108414-e108414 (2014-10-01)
There are currently no established radiological parameters that predict response to immunotherapy. We hypothesised that multiparametric, longitudinal magnetic resonance imaging (MRI) of physiological parameters and pharmacokinetic models might detect early biological responses to immunotherapy for glioblastoma targeting NG2/CSPG4 with mAb9.2.27
R J Robb et al.
Proceedings of the National Academy of Sciences of the United States of America, 81(20), 6486-6490 (1984-10-01)
Human interleukin 2 was separated into multiple molecular forms by selective immunoaffinity chromatography and chromatofocusing. For the most part, this heterogeneity was attributed to variations in glycosylation of the threonine residue in position 3 of the polypeptide chain. The various

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