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Merck
CN

57600

Sigma-Aldrich

IL-2 human

≥98% (GE), recombinant, expressed in E. coli, liquid

别名:

IL-2, TCGF, hIL-2

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关于此项目

CAS Number:
MDL编号:
UNSPSC代码:
12352202
NACRES:
NA.32
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Product Name

白细胞介素-2 人, recombinant, expressed in E. coli, ~10000 U/mL

生物来源

human

质量水平

重组

expressed in E. coli

表单

liquid

分子量

Mr ~15500

包装

vial of 1 mL

浓度

~10000 U/mL

颜色

colorless

UniProt登记号

运输

dry ice

储存温度

−70°C

基因信息

human ... IL2(3558)

生化/生理作用

促进IL-2依赖性淋巴细胞的生长。 IL-2的氨基酸序列。

包装

一瓶含10′000单位

外形

透明无色的溶液,溶剂为Dulbecco-PBS;含1 mg BSA/mL。

其他说明

1个单位对应于CTLL-2细胞的比色MTT分析中的单位活性。
可能适用相应的销售限制。

免责声明

在−20 °C下稳定;准备合适的分装品,避免反复冻融,否则可能会发生聚集,导致活性明显下降。

储存分类代码

10 - Combustible liquids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

常规特殊物品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Interleukin 2.
K A Smith
Annual review of immunology, 2, 319-333 (1984-01-01)
S Gillis et al.
Journal of immunology (Baltimore, Md. : 1950), 120(6), 2027-2032 (1978-06-01)
Several soluble factors have recently been associated with the proliferation and differentiation of thymus-derived lymphocytes. One of these factors present in medium conditioned by T cell mitogen-stimulated lymphocytes has the ability to promote the long-term culture of normal and antigen-specific
R J Robb et al.
Proceedings of the National Academy of Sciences of the United States of America, 81(20), 6486-6490 (1984-10-01)
Human interleukin 2 was separated into multiple molecular forms by selective immunoaffinity chromatography and chromatofocusing. For the most part, this heterogeneity was attributed to variations in glycosylation of the threonine residue in position 3 of the polypeptide chain. The various
Denise L Cecil et al.
Cancer research, 74(10), 2710-2718 (2014-04-30)
Immunization against self-tumor antigens can induce T-regulatory cells, which inhibit proliferation of type I CD4(+) T-helper (TH1) and CD8(+) cytotoxic T cells. Type I T cells are required for potent antitumor immunity. We questioned whether immunosuppressive epitopes could be identified
Cecilie Brekke Rygh et al.
PloS one, 9(9), e108414-e108414 (2014-10-01)
There are currently no established radiological parameters that predict response to immunotherapy. We hypothesised that multiparametric, longitudinal magnetic resonance imaging (MRI) of physiological parameters and pharmacokinetic models might detect early biological responses to immunotherapy for glioblastoma targeting NG2/CSPG4 with mAb9.2.27

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