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经验公式(希尔记法):
C19H13ClIN5O2
化学文摘社编号:
分子量:
505.70
UNSPSC Code:
12352102
NACRES:
NA.25
PubChem Substance ID:
EC Number:
205-676-2
Beilstein/REAXYS Number:
4093224
MDL number:
Assay:
≥97.0% (calc. on dry substance, NT)
InChI key
JORABGDXCIBAFL-UHFFFAOYSA-M
InChI
1S/C19H13IN5O2.ClH/c20-15-6-8-16(9-7-15)23-21-19(14-4-2-1-3-5-14)22-24(23)17-10-12-18(13-11-17)25(26)27;/h1-13H;1H/q+1;/p-1
SMILES string
[Cl-].[O-][N+](=O)c1ccc(cc1)-[n+]2nc(nn2-c3ccc(I)cc3)-c4ccccc4
product line
BioReagent
assay
≥97.0% (calc. on dry substance, NT)
mp
240 °C (dec.) (lit.), ~245 °C (dec.)
solubility
methanol: water (1:1): 50 mg/mL, very faintly turbid, very deep yellow (hot)
application(s)
histology
Quality Level
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Application
多种脱氢酶比色分析中的电子受体
碘硝基四唑(INT)是一种四唑染料前体,在还原时形成紫色甲瓒染料,已用于多种应用。它被认为比某些四唑化合物具有更高的反应性,至少就琥珀酸脱氢酶而言,使用0.8 mM INT的浓度可获得最佳结果。INT用作比色测定的电子受体:乳酸脱氢酶、黄嘌呤脱氢酶、乳酰辅酶A脱氢酶、琥珀酸脱氢酶、BBM II酮异构酶、组氨酸脱氢酶和多种其他水解酶。
signalword
Danger
hcodes
Hazard Classifications
Flam. Sol. 1 - STOT SE 3
target_organs
Respiratory system
存储类别
4.1B - Flammable solid hazardous materials
wgk
WGK 3
ppe
Eyeshields, Gloves, type N95 (US)
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Antoine Picciocchi et al.
The Journal of biological chemistry, 286(32), 28357-28369 (2011-06-11)
Flavocytochrome b(558) (cytb) of phagocytes is a heterodimeric integral membrane protein composed of two subunits, p22(phox) and gp91(phox). The latter subunit, also known as Nox2, has a cytosolic C-terminal "dehydrogenase domain" containing FAD/NADPH-binding sites. The N-terminal half of Nox2 contains
Matthildi Valianou et al.
Scientific reports, 9(1), 3015-3015 (2019-03-01)
Tuberous Sclerosis Complex (TSC) and Lymphangioleiomyomatosis (LAM) are caused by inactivating mutations in TSC1 or TSC2, leading to mTORC1 hyperactivation. The mTORC1 inhibitors rapamycin and analogs (rapalogs) are approved for treating of TSC and LAM. Due to their cytostatic and
Ruiwu Wang et al.
Insect biochemistry and molecular biology, 33(7), 733-739 (2003-06-27)
Voltage-gated sodium channels are essential for the generation and propagation of action potentials in most excitable cells. They are the target sites of several classes of insecticides and acaricides. Isolation of full-length sodium channel cDNA is a critical and often
Yang Hongwei et al.
Ecotoxicology and environmental safety, 53(3), 416-421 (2002-12-18)
This study assessed anaerobic biodegradability of organic compounds from microorganism activity. Dehydrogenase activity can be a good parameter characterizing the microorganism activity. A modified method of 2-(p-iodophenyl-3-(p-nitrophenyl)-5-pheny tetrazolium chloride-dehydrogenase activity determination was proposed in anaerobic biodegradability assessment. Cubic spline curves
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