58030
氯化碘硝基四氮唑
BioReagent, ≥97.0% (calc. on dry substance, NT)
别名:
2-(4-碘苯基)-3-(4-硝基苯基)-5-苯基氯化四唑氯水合物, INT, 对碘硝基四唑紫
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关于此项目
经验公式（希尔记法）:
C19H13ClIN5O2
化学文摘社编号:
分子量:
505.70
UNSPSC Code:
12352102
NACRES:
NA.25
PubChem Substance ID:
EC Number:
205-676-2
Beilstein/REAXYS Number:
4093224
MDL number:
产品名称
氯化碘硝基四氮唑, BioReagent, ≥97.0% (calc. on dry substance, NT)
InChI key
JORABGDXCIBAFL-UHFFFAOYSA-M
InChI
1S/C19H13IN5O2.ClH/c20-15-6-8-16(9-7-15)23-21-19(14-4-2-1-3-5-14)22-24(23)17-10-12-18(13-11-17)25(26)27;/h1-13H;1H/q+1;/p-1
SMILES string
[Cl-].[O-][N+](=O)c1ccc(cc1)-[n+]2nc(nn2-c3ccc(I)cc3)-c4ccccc4
product line
BioReagent
assay
≥97.0% (calc. on dry substance, NT)
mp
240 °C (dec.) (lit.)
~245 °C (dec.)
solubility
methanol: water (1:1): 50 mg/mL, very faintly turbid, very deep yellow (hot)
application(s)
histology
Quality Level
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Application
多种脱氢酶比色分析中的电子受体
碘硝基四唑（INT）是一种四唑染料前体，在还原时形成紫色甲瓒染料，已用于多种应用。它被认为比某些四唑化合物具有更高的反应性，至少就琥珀酸脱氢酶而言，使用0.8 mM INT的浓度可获得最佳结果。INT用作比色测定的电子受体：乳酸脱氢酶、黄嘌呤脱氢酶、乳酰辅酶A脱氢酶、琥珀酸脱氢酶、BBM II酮异构酶、组氨酸脱氢酶和多种其他水解酶。
signalword
Danger
hcodes
Hazard Classifications
Flam. Sol. 1 - STOT SE 3
target_organs
Respiratory system
存储类别
4.1B - Flammable solid hazardous materials
wgk
WGK 3
ppe
Eyeshields, Gloves, type N95 (US)
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Antoine Picciocchi et al.
The Journal of biological chemistry, 286(32), 28357-28369 (2011-06-11)
Flavocytochrome b(558) (cytb) of phagocytes is a heterodimeric integral membrane protein composed of two subunits, p22(phox) and gp91(phox). The latter subunit, also known as Nox2, has a cytosolic C-terminal "dehydrogenase domain" containing FAD/NADPH-binding sites. The N-terminal half of Nox2 contains
F Mermillod-Blondin et al.
Water research, 39(9), 1687-1698 (2005-05-19)
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T J Mankelow et al.
The Biochemical journal, 358(Pt 2), 315-324 (2001-08-22)
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