58756
1-(5-Isoquinolinesulfonyl)-3-methylpiperazine
≥98.0% (HPLC)
别名:
1-(5-硫代异喹啉)-3-甲基哌嗪, Iso-H-7
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关于此项目
经验公式（希尔记法）:
C14H17N3O2S
化学文摘社编号:
分子量:
291.37
Beilstein:
5445506
MDL编号:
UNSPSC代码:
12352202
PubChem化学物质编号:
NACRES:
NA.77
质量水平
方案
≥98.0% (HPLC)
表单
powder
储存温度
2-8°C
SMILES字符串
CC1CN(CCN1)S(=O)(=O)c2cccc3cnccc23
InChI
1S/C14H17N3O2S/c1-11-10-17(8-7-16-11)20(18,19)14-4-2-3-12-9-15-6-5-13(12)14/h2-6,9,11,16H,7-8,10H2,1H3
InChI key
QGSCXAWTTISKLF-UHFFFAOYSA-N
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相关类别
生化/生理作用
Less potent inhibitor of protein kinaseC than H-7
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
K Fujisawa et al.
Placenta, 21(4), 354-360 (2000-06-02)
To clarify the biological and pathological features of choriocarcinoma, we evaluated the in vitro production of cytokines by a choriocarcinoma cell line, BeWo. We measured the concentration of interleukin (IL)-6 and IL-8 in the culture media of BeWo cells after
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C C Chua et al.
Biochimica et biophysica acta, 1401(2), 187-194 (1998-04-09)
Vascular endothelial growth factor (VEGF) is a potent mitogen for endothelial cells and a vascular permeability factor. In this study we found that the addition of angiotensin II (AII) to rat heart endothelial cells induced VEGF mRNA production. VEGF mRNA
J Duraj et al.
Neoplasma, 44(4), 205-211 (1997-01-01)
The human pre-B acute lymphoblastic leukemia cell line REH6 was utilized for characterization of CD45 glycoprotein by monoclonal antibodies (mAb) recognizing four distinct CD45 antigen specificities, i.e. nonrestricted CD45, restricted CD45RA, CD45RB and CD45R0. Immunoprecipitation revealed two antigen specificities on
A Symes et al.
The Journal of biological chemistry, 272(15), 9648-9654 (1997-04-11)
Ciliary neurotrophic factor (CNTF)-dependent induction of expression of the neuropeptide vasoactive intestinal peptide (VIP) gene is mediated by a 180-base pair cytokine response element (CyRE) in the VIP promoter. To elucidate the molecular mechanisms mediating the transcriptional activation by CNTF
Mei-Hua Li et al.
Zhonghua er bi yan hou ke za zhi, 39(6), 353-355 (2004-10-08)
To study the influence of the inhibitor of protein kinase C (PKC), Iso-H7 [1-(5-lsoquinolinyl-sulfony)-3-methylpiperazine dihydrochloride] on eosinophil apoptosis in nasal polyp tissues. Nasal polyp tissues were cultured and divided into two groups, test group (with Iso-H7 in different concentration) and
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