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Merck
CN

60178

氰化钾

BioUltra, ≥98.0% (AT)

别名:

KCN, Potassium salt of hydrocyanic acid

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关于此项目

线性分子式:
KCN
化学文摘社编号:
分子量:
65.12
UNSPSC Code:
12352302
NACRES:
NA.25
PubChem Substance ID:
EC Number:
205-792-3
Beilstein/REAXYS Number:
3593645
MDL number:
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产品名称

氰化钾, BioUltra, ≥98.0% (AT)

InChI key

YUZRZFQHUCKACF-UHFFFAOYSA-N

InChI

1S/CN.K/c1-2;

SMILES string

[K]C#N

biological source

synthetic

product line

BioUltra

assay

≥98.0% (AT)

form

crystalline

impurities

insoluble matter, passes filter test

pH

11.0-13.0 (25 °C, 1 M in H2O)

mp

634 °C (lit.)

solubility

H2O: 1 M at 20 °C, clear, colorless

anion traces

chloride (Cl-): ≤200 mg/kg
sulfate (SO42-): ≤400 mg/kg
sulfide (S2-): ≤5 mg/kg
thiocyanate (SCN-): ≤100 mg/kg

cation traces

Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤50 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤100 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Na: ≤5000 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

λ

1 M in H2O

UV absorption

λ: 260 nm Amax: 0.06
λ: 280 nm Amax: 0.03

Quality Level

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Application

Potassium cyanide is use to inhibit oxidative phosphorylation reactions in a wide variety of biological systems and applications.

Other Notes

Blocks electron transport to oxygen via cytochrome oxidase, hence employed in the determination of succinate dehydrogenase in submitochondrial particles by preventing substantial loss of succinate by electron flux to O2

signalword

Danger

Hazard Classifications

Acute Tox. 1 Oral - Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Aquatic Acute 1 - Aquatic Chronic 1 - Met. Corr. 1 - STOT RE 1

target_organs

Thyroid

supp_hazards

存储类别

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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EPR and other properties of succinate dehydrogenase.
T Ohnishi et al.
Methods in enzymology, 53, 483-495 (1978-01-01)
Pascaline Clerc et al.
Journal of bioenergetics and biomembranes, 39(2), 158-166 (2007-04-21)
We have studied the effect of nitric oxide (NO) and potassium cyanide (KCN) on oxidative phosphorylation efficiency. Concentrations of NO or KCN that decrease resting oxygen consumption by 10-20% increased oxidative phosphorylation efficiency in mitochondria oxidizing succinate or palmitoyl-L-carnitine, but
Yudong Wang et al.
The Journal of biological chemistry, 285(39), 29834-29841 (2010-07-29)
Fatty acid β-oxidation (FAO) and oxidative phosphorylation (OXPHOS) are key pathways involved in cellular energetics. Reducing equivalents from FAO enter OXPHOS at the level of complexes I and III. Genetic disorders of FAO and OXPHOS are among the most frequent
Mammalian succinate dehydrogenase.
B A Ackrell et al.
Methods in enzymology, 53, 466-483 (1978-01-01)
Takeshi Hatani et al.
Biochemical and biophysical research communications, 505(4), 1251-1256 (2018-10-20)
Many studies have shown the feasibility of in vivo cardiac transplantation of human induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) in animal experiments. However, nano-structural confirmation of the successful incorporation of the engrafted iPSC-CMs including electron microscopy (EM) has not been accomplished

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