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Merck
CN

60178

Sigma-Aldrich

氰化钾

BioUltra, ≥98.0% (AT)

别名:

KCN, Potassium salt of hydrocyanic acid

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关于此项目

线性分子式:
KCN
化学文摘社编号:
分子量:
65.12
Beilstein:
3593645
EC 号:
MDL编号:
UNSPSC代码:
12352302
PubChem化学物质编号:
NACRES:
NA.25
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生物来源

synthetic

产品线

BioUltra

方案

≥98.0% (AT)

表单

crystalline

杂质

insoluble matter, passes filter test

pH值(酸碱度)

11.0-13.0 (25 °C, 1 M in H2O)

mp

634 °C (lit.)

溶解性

H2O: 1 M at 20 °C, clear, colorless

痕量阴离子

chloride (Cl-): ≤200 mg/kg
sulfate (SO42-): ≤400 mg/kg
sulfide (S2-): ≤5 mg/kg
thiocyanate (SCN-): ≤100 mg/kg

痕量阳离子

Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤50 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤100 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Na: ≤5000 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

λ

1 M in H2O

紫外吸收

λ: 260 nm Amax: 0.06
λ: 280 nm Amax: 0.03

SMILES字符串

[K]C#N

InChI

1S/CN.K/c1-2;

InChI key

YUZRZFQHUCKACF-UHFFFAOYSA-N

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应用

Potassium cyanide is use to inhibit oxidative phosphorylation reactions in a wide variety of biological systems and applications.

其他说明

Blocks electron transport to oxygen via cytochrome oxidase, hence employed in the determination of succinate dehydrogenase in submitochondrial particles by preventing substantial loss of succinate by electron flux to O2

警示用语:

Danger

危险分类

Acute Tox. 1 Oral - Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Aquatic Acute 1 - Aquatic Chronic 1 - Met. Corr. 1 - STOT RE 1

靶器官

Thyroid

补充剂危害

储存分类代码

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

监管及禁止进口产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

EPR and other properties of succinate dehydrogenase.
T Ohnishi et al.
Methods in enzymology, 53, 483-495 (1978-01-01)
Pascaline Clerc et al.
Journal of bioenergetics and biomembranes, 39(2), 158-166 (2007-04-21)
We have studied the effect of nitric oxide (NO) and potassium cyanide (KCN) on oxidative phosphorylation efficiency. Concentrations of NO or KCN that decrease resting oxygen consumption by 10-20% increased oxidative phosphorylation efficiency in mitochondria oxidizing succinate or palmitoyl-L-carnitine, but
Yudong Wang et al.
The Journal of biological chemistry, 285(39), 29834-29841 (2010-07-29)
Fatty acid β-oxidation (FAO) and oxidative phosphorylation (OXPHOS) are key pathways involved in cellular energetics. Reducing equivalents from FAO enter OXPHOS at the level of complexes I and III. Genetic disorders of FAO and OXPHOS are among the most frequent
Mammalian succinate dehydrogenase.
B A Ackrell et al.
Methods in enzymology, 53, 466-483 (1978-01-01)
Takeshi Hatani et al.
Biochemical and biophysical research communications, 505(4), 1251-1256 (2018-10-20)
Many studies have shown the feasibility of in vivo cardiac transplantation of human induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) in animal experiments. However, nano-structural confirmation of the successful incorporation of the engrafted iPSC-CMs including electron microscopy (EM) has not been accomplished

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