61962
甜菜碱
BioUltra, ≥99.0% (NT)
别名:
Oxyneurine, Trimethylglycine, （羧甲基）三甲胺 内盐
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关于此项目
线性分子式:
(CH3)3N+CH2COO-
化学文摘社编号:
分子量:
117.15
UNSPSC Code:
41116107
NACRES:
NA.25
PubChem Substance ID:
EC Number:
203-490-6
Beilstein/REAXYS Number:
3537113
MDL number:
产品名称
甜菜碱, BioUltra, ≥99.0% (NT)
InChI key
KWIUHFFTVRNATP-UHFFFAOYSA-N
InChI
1S/C5H11NO2/c1-6(2,3)4-5(7)8/h4H2,1-3H3
SMILES string
C[N+](C)(C)CC([O-])=O
product line
BioUltra
assay
≥99.0% (NT)
impurities
insoluble matters, passes filter test
solubility
methanol: 1 M at 20 °C, clear, colorless
anion traces
chloride (Cl-): ≤200 mg/kg
sulfate (SO42-): ≤200 mg/kg
cation traces
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Na: ≤100 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg
Ca: ≤20 mg/kg
absorption
≤0.05 at 280 nm in methanol at 1 M
≤0.09 at 260 nm in methanol at 1 M
Quality Level
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Application
甜菜碱已被用于逆转录以增加蛋白质的热稳定性并使DNA螺旋脱稳。
Biochem/physiol Actions
甜菜碱已被证明可增加S-腺苷甲硫氨酸（SAM）水平，因此可能在减少肝脏脂肪变性方面发挥作用。它是一种渗透压保护剂，可保护细胞免受环境压力的影响。
甜菜碱是胆碱氧化代谢的终产物，是一种通用的甲基供体，特别存在于甲硫氨酸生物合成的一个次要途径中。它被用于治疗同型半胱氨酸尿症，一种在蛋氨酸生物合成主要途径的缺陷。
General description
我们全面的上游工艺化学品系列不仅为生物制药生产商提供生产传统和创新治疗药物所需的优质原料，而且帮助他们更快地将产品投放市场并简化监管问题。 请相信我们能够为您带来透明的供应链和可靠的全球采购能力，以最佳的法规支持和服务简化您的产品认证。
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Full-length RNA-seq from single cells using Smart-seq2.
Picelli S
Nature Protocols, 9(1), 171-181 (2014)
Varsha Mathur et al.
Current biology : CB, 29(17), 2936-2941 (2019-08-20)
The apicomplexans are a group of obligate animal pathogens that include Plasmodium (malaria), Toxoplasma (toxoplasmosis), and Cryptosporidium (cryptosporidiosis) [1]. They are an extremely diverse and specious group but are nevertheless united by a distinctive suite of cytoskeletal and secretory structures related to
Shangli Cheng et al.
Cell reports, 26(10), 2593-2607 (2019-03-07)
Following implantation, the epiblast (EPI) cells transit from the naive to primed pluripotency, accompanied by dynamic changes in X chromosome activity in females. To investigate the molecular attributes of this process, we performed single-cell RNA-seq analysis of 1,724 cells of
M R Olthof et al.
Current drug metabolism, 6(1), 15-22 (2005-02-22)
High plasma concentrations of homocysteine may increase risk of cardiovascular disease. Folic acid lowers plasma homocysteine by 25% maximally, because 5-methyltetrahydrofolate is a methyl donor in the remethylation of homocysteine to methionine. Betaine (trimethylglycine) is also a methyl donor in
Bernd C Schwahn et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 17(3), 512-514 (2003-01-29)
Hyperhomocysteinemia, a proposed risk factor for cardiovascular disease, is also observed in other common disorders. The most frequent genetic cause of hyperhomocysteinemia is a mutated methylenetetrahydrofolate reductase (MTHFR), predominantly when folate status is impaired. MTHFR synthesizes a major methyl donor
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