产品名称
L-α-溶血磷脂酰胆碱, egg yolk, ≥99.0% (TLC)
biological source
egg yolk
description
zwitterionic
assay
≥99.0% (TLC)
form
powder or solid
composition
16:0, ~69% (fatty acid)
18:0, ~27% (fatty acid)
18:1, ~3% (fatty acid)
solubility
chloroform/methanol: 50 mg/mL, clear, colorless to very faintly yellow
functional group
phospholipid
lipid type
phosphoglycerides
shipped in
wet ice
storage temp.
−20°C
Other Notes
去膜青蛙精子染色质制剂
Application
- 溶血磷脂酰胆碱对机械敏感离子通道MscL的激活模式不同于张力诱导门控：L-α-LPC因其与离子通道之间存在独特的相互作用而受到关注，表明它有可能成为研究通道力学和为细胞力学相关疾病开发新治疗策略的工具（Mukherjee et al., 2014）。
- 使用气管内导管将增强型辅助病毒依赖型腺病毒制剂气溶胶递送到兔肺部：使用L-α-LPC可增强基因治疗载体的气溶胶递送，表明其能有效提高基因治疗效率，特别是对于呼吸系统疾病（Koehler et al., 2005）。
Biochem/physiol Actions
3-sn-溶血磷脂酰胆碱不仅有助于改善膜的正曲率，还能抑制体外以及大鼠神经末梢和外分泌胰腺中SNARE复合物的解体。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Nuclear envelope assembly following mitosis.
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Harvey T McMahon et al.
Nature, 438(7068), 590-596 (2005-12-02)
Membrane curvature is no longer seen as a passive consequence of cellular activity but an active means to create membrane domains and to organize centres for membrane trafficking. Curvature can be dynamically modulated by changes in lipid composition, the oligomerization
Priscila M Hiraiwa et al.
Cytometry. Part A : the journal of the International Society for Analytical Cytology, 93(7), 727-736 (2018-08-18)
Trypanosomatid parasites are causative agents of neglected human diseases. Their lineage diverged early from the common eukaryotic ancestor, and they evolved singular mechanisms of gene expression that are crucial for their survival. Studies on unusual and essential molecular pathways lead
Fengfeng Lu et al.
Neuroscience bulletin, 35(3), 434-446 (2019-01-27)
The obstacle to successful remyelination in demyelinating diseases, such as multiple sclerosis, mainly lies in the inability of oligodendrocyte precursor cells (OPCs) to differentiate, since OPCs and oligodendrocyte-lineage cells that are unable to fully differentiate are found in the areas
Beibei Duan et al.
Molecules (Basel, Switzerland), 26(6) (2021-04-04)
Fat globule size and phospholipid (PL) content in human milk (HM) were investigated. HM was classified into three groups depending on fat content (A < B < C). PL content (mg/100 g HM) was significantly higher in the C group
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