63226
Benzamidine hydrochloride 1 M solution
别名:
Benzamidine hydrochloride solution, Additive Screening Solution 37/Kit-No 78374
储存温度
2-8°C
质量水平
SMILES字符串
Cl.NC(=N)c1ccccc1
InChI
1S/C7H8N2.ClH/c8-7(9)6-4-2-1-3-5-6;/h1-5H,(H3,8,9);1H
InChI key
LZCZIHQBSCVGRD-UHFFFAOYSA-N
储存分类代码
10 - Combustible liquids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves
Ryan Walsh et al.
Integrative biology : quantitative biosciences from nano to macro, 3(12), 1197-1201 (2011-11-01)
Enzyme inhibitors are usually classified as competitive, non-competitive or mixed non-competitive. Each of these designations has a serious limitation in that it only describes an extreme of inhibitory behaviour. The non-competitive inhibition equation only considers an approach to complete inhibition
Dian Jiao et al.
Journal of computational chemistry, 30(11), 1701-1711 (2009-04-29)
We have calculated the binding free energies of a series of benzamidine-like inhibitors to trypsin with a polarizable force field using both explicit and implicit solvent approaches. Free energy perturbation has been performed for the ligands in bulk water and
Luca Mannocci et al.
Bioconjugate chemistry, 21(10), 1836-1841 (2010-09-03)
Collections of chemical compounds, individually attached to unique DNA fragments serving as amplifiable identification bar codes, are generally referred to as "DNA-encoded chemical libraries". Such libraries can be used for the de novo isolation of binding molecules against target proteins
Joseph Vamecq et al.
European journal of medicinal chemistry, 45(7), 3101-3110 (2010-04-30)
Five bis-benzamidines were screened towards murine magnesium deficiency-dependent audiogenic seizures, unravelling two compounds with efficacious doses 50 (ED(50)) less than 10mg/kg. They were also screened against maximal electroshock and subcutaneous pentylenetetrazole-induced seizures, and explored for superoxide -scavenging activity. 1,2-Ethane bis-1-amino-4-benzamidine
Single-molecule approach to DNA minor-groove association dynamics.
Jorge Bordello et al.
Angewandte Chemie (International ed. in English), 51(30), 7541-7544 (2012-06-16)
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