63410
丙二酰胺辅酶A 四锂盐
≥90% (HPLC)
别名:
丙二酰胺辅酶a四锂盐
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关于此项目
经验公式（希尔记法）:
C24H34Li4N7O19P3S
化学文摘社编号:
分子量:
877.31
MDL编号:
UNSPSC代码:
41106305
PubChem化学物质编号:
NACRES:
NA.51
质量水平
方案
≥90% (HPLC)
表单
solid
杂质
≤12% water
溶解性
H2O: 50 mg/mL, clear, colorless
储存温度
−20°C
SMILES字符串
[Li+].[Li+].[Li+].[Li+].CC(C)(COP([O-])(=O)OP([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP([O-])([O-])=O)n2cnc3c(N)ncnc23)[C@@H](O)C(=O)NCCC(=O)NCCSC(=O)CC(O)=O
InChI
1S/C24H38N7O19P3S.4Li/c1-24(2,19(37)22(38)27-4-3-13(32)26-5-6-54-15(35)7-14(33)34)9-47-53(44,45)50-52(42,43)46-8-12-18(49-51(39,40)41)17(36)23(48-12)31-11-30-16-20(25)28-10-29-21(16)31;;;;/h10-12,17-19,23,36-37H,3-9H2,1-2H3,(H,26,32)(H,27,38)(H,33,34)(H,42,43)(H,44,45)(H2,25,28,29)(H2,39,40,41);;;;/q;4*+1/p-4/t12-,17-,18-,19+,23-;;;;/m1..../s1
InChI key
DQLXXYMNINXQSV-QTRRCMKVSA-J
生化/生理作用
丙二酰辅酶A是一种辅酶A衍生物，可用于脂肪酸和聚酮合成，以及胯线粒体膜转移酮戊二酸。丙二酰辅酶A是由乙酰辅酶A羧化酶介导的乙酰辅酶A的羧化反应形成的。
其他说明
丙二酰胺辅酶a在克隆胰岛β细胞葡萄糖刺激的胰岛素分泌中的作用
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
B E Corkey et al.
The Journal of biological chemistry, 264(36), 21608-21612 (1989-12-25)
To gain insight into the relationship between acyl coenzyme A (CoA) esters and glucose-induced insulin release, acyl-CoA profiles were determined in clonal pancreatic beta-cells (HIT). A high sensitivity high performance liquid chromatography method was used to measure malonyl, succinyl, beta-hydroxy
Christopher J Arthur et al.
ACS chemical biology, 4(8), 625-636 (2009-06-27)
Malonylation of an acyl carrier protein (ACP) by malonyl Coenzyme A-ACP transacylase (MCAT) is fundamental to bacterial fatty acid biosynthesis. Here, we report the structure of the Steptomyces coelicolor (Sc) fatty acid synthase (FAS) ACP and studies of its binding
Dea Hwan Kim et al.
Plant physiology and biochemistry : PPB, 47(11-12), 991-997 (2009-09-08)
In this study, a flavonoid malonyltransferase (OsMaT-2) was cloned from Oryza sativa, and the recombinant protein OsMaT-2 was purified via affinity chromatography. OsMaT-2 utilized a variety of flavonoid glucosides, including flavanone glucosides, flavone glucosides, flavonol glucosides, and isoflavone glucosides as
Heather Seidle et al.
Journal of bacteriology, 186(8), 2499-2503 (2004-04-03)
Cfa1 was overproduced in Escherichia coli and Pseudomonas syringae, and the degree of 4'-phosphopantetheinylation was determined. The malonyl-coenzyme A:acyl carrier protein transacylase (FabD) of P. syringae was overproduced and shown to catalyze malonylation of Cfa1, suggesting that FabD plays a
Koichiro Kogawa et al.
Journal of plant physiology, 164(7), 886-894 (2006-08-05)
The crude malonyltransferase from the petals of Clitoria ternatea was characterized enzymatically to investigate its role on the biosynthetic pathways of anthocyanins and flavonol glycosides. In C. ternatea, a blue flower cultivars (DB) and mauve flower variety (WM) accumulate polyacylated
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