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Merck
CN

68338

Sigma-Aldrich

2-甲基-2,4-戊二醇

BioUltra, ≥99.0% (GC)

别名:

(±)-2-甲基-2,4-戊二醇, MPD

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关于此项目

线性分子式:
CH3CH(OH)CH2C(CH3)2OH
化学文摘社编号:
分子量:
118.17
Beilstein:
1098298
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.26
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蒸汽密度

4.1 (vs air)

蒸汽压

0.02 mmHg ( 20 °C)

产品线

BioUltra

方案

≥99.0% (GC)

表单

liquid (or viscous liquid)

expl. lim.

7.4 %

杂质

insoluble matter, passes filter test

折射率

n20/D 1.427 (lit.)
n20/D 1.428

pH值(酸碱度)

6-8 (25 °C, 1 M in H2O)

沸点

197 °C (lit.)

mp

−40 °C (lit.)

溶解性

H2O: 1 M at 20 °C, clear, colorless

密度

0.925 g/mL at 25 °C (lit.)

痕量阴离子

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤50 mg/kg

痕量阳离子

Al: ≤1 mg/kg
As: ≤0.1 mg/kg
Ba: ≤1 mg/kg
Bi: ≤1 mg/kg
Ca: ≤5 mg/kg
Cd: ≤1 mg/kg
Co: ≤1 mg/kg
Cr: ≤1 mg/kg
Cu: ≤1 mg/kg
Fe: ≤1 mg/kg
K: ≤20 mg/kg
Li: ≤1 mg/kg
Mg: ≤1 mg/kg
Mn: ≤1 mg/kg
Mo: ≤1 mg/kg
Na: ≤20 mg/kg
Ni: ≤1 mg/kg
Pb: ≤1 mg/kg
Sr: ≤1 mg/kg
Zn: ≤1 mg/kg

λ

1 M in H2O

紫外吸收

λ: 260 nm Amax: 0.01
λ: 280 nm Amax: 0.01

SMILES字符串

CC(O)CC(C)(C)O

InChI

1S/C6H14O2/c1-5(7)4-6(2,3)8/h5,7-8H,4H2,1-3H3

InChI key

SVTBMSDMJJWYQN-UHFFFAOYSA-N

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其他说明

Used in the crystallisation of proteins

象形图

Health hazardExclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2

储存分类代码

10 - Combustible liquids

WGK

WGK 1

闪点(°F)

201.2 °F - closed cup

闪点(°C)

94 °C - closed cup

个人防护装备

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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A.M. Brzozowski et al.
Journal of Applied Crystallography, 34, 97-97 (2001)
Kanchan Anand et al.
Acta crystallographica. Section D, Biological crystallography, 58(Pt 10 Pt 1), 1722-1728 (2002-09-28)
2-Methyl-2,4-pentanediol (MPD) is the most popular chemical additive used for crystallization of biological macromolecules. However, the mechanism of its action on proteins in aqueous solution is not well understood. We have carried out a systematic analysis of the conformation and
Jose Antonio Cuesta-Seijo et al.
Structure (London, England : 1993), 18(9), 1210-1219 (2010-09-10)
Enzymatic reactions involving bilayer lipids occur in an environment with strict physical and topological constraints. The integral membrane enzyme PagP transfers a palmitoyl group from a phospholipid to lipid A in order to assist Escherichia coli in evading host immune
Catherine Michaux et al.
Journal of molecular biology, 375(5), 1477-1488 (2007-12-18)
Sodium dodecyl sulfate (SDS) is a highly effective and widely used protein denaturant. We show that certain amphipathic cosolvents such as 2-methyl-2,4-pentanediol (MPD) can protect proteins from SDS denaturation, and in several cases can refold proteins from the SDS-denatured state.
Yoshikazu Tanaka et al.
Protein science : a publication of the Protein Society, 20(2), 448-456 (2011-02-01)
Staphylococcal α-hemolysin is expressed as a water-soluble monomeric protein and assembles on membranes to form a heptameric pore structure. The heptameric pore structure of α-hemolysin can be prepared from monomer in vitro only in the presence of deoxycholate detergent micelles

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