68783
甘草查尔酮A
≥96.0% (HPLC)
别名:
(E)-3- [5-（1,1-二甲基-2-丙烯基）-4-羟基-2-甲氧基苯基]-1-（4-羟基苯基）-2-丙烯-1-酮, 4′1,4-二羟基-3-α,α-二甲基烯丙基-6-甲氧基查尔酮
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关于此项目
经验公式（希尔记法）:
C21H22O4
化学文摘社编号:
分子量:
338.40
Beilstein:
4534154
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.77
一般描述
Licochalcone A 是一种强效膜活性剂，可将正常红细胞转化为棘形红细胞。一种具有显著抗肿瘤活性的新型黄酮类化合物。
生化/生理作用
抑制芽孢形成细菌 枯草芽孢杆菌 和其他食品污染微生物的营养生长。
包装
无底玻璃瓶。内含物装在插入的融合锥内。
警示用语：
Warning
危险分类
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Yoon Hee Kim et al.
Biochemical pharmacology, 80(8), 1152-1159 (2010-07-20)
To date, no antiangiogenic activity has been demonstrated for licochalcone A (LicA), a major phenolic constituent of Glycyrrhiza inflata, although it shows significant antitumor activity in human malignant cell lines. Our previous work demonstrated that LicA down-regulates inflammatory responses to
Hanne L Ziegler et al.
Antimicrobial agents and chemotherapy, 48(10), 4067-4071 (2004-09-25)
The well-known antiparasitic compound licochalcone A is a potent membrane-active agent that transforms normal erythrocytes into echinocytes in parallel with the inhibition of growth of Plasmodium falciparum cultures, the in vitro antiplasmodial effect apparently being an indirect effect on the
Xiao Chu et al.
Journal of agricultural and food chemistry, 60(15), 3947-3954 (2012-03-10)
Licochalcone A (Lico A), a flavonoid found in licorice root (Glycyrrhiza glabra), is known for its antimicrobial activity and its reported ability to inhibit cancer cell proliferation. In the present study, we found that Lico A exerted potent anti-inflammatory effects
Yi-Te Yo et al.
Journal of agricultural and food chemistry, 57(18), 8266-8273 (2009-08-29)
Licorice is a common Chinese medicinal herb with antitumor activity. Some components in licorice root have been shown to induce cell cycle arrest or apoptosis in cancer cells. This paper demonstrates for the first time that licorice Glycyrrhiza glabra and
Megumi Funakoshi-Tago et al.
Molecular pharmacology, 76(4), 745-753 (2009-07-14)
Glycyrrhiza inflata has been used as a traditional medicine with anti-inflammatory activity; however, its mechanism has not been fully understood. Licochalcone A is a major and biogenetically characteristic chalcone isolated from G. inflata. Here, we found that licochalcone A strongly
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