72779
三氯生
97.0-103.0% (active substance, GC)
别名:
三氯苯氧氯酚, 5-氯-2-（2,4-二氯苯氧基）苯酚, 氯苯酚
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关于此项目
经验公式（希尔记法）:
C12H7Cl3O2
化学文摘社编号:
分子量:
289.54
UNSPSC Code:
12352132
NACRES:
NA.85
PubChem Substance ID:
EC Number:
222-182-2
Beilstein/REAXYS Number:
2057142
MDL number:
biological source
synthetic
Quality Level
assay
97.0-103.0% (active substance, GC)
form
powder or crystals
impurities
≤0.1% Water (Karl Fischer)
color
white
mp
55-59 °C
solubility
1 M NaOH: 5% at 25 °C, faintly turbid to clear (colorless solution)
antibiotic activity spectrum
fungi
mode of action
enzyme | inhibits
SMILES string
Oc1cc(Cl)ccc1Oc2ccc(Cl)cc2Cl
InChI
1S/C12H7Cl3O2/c13-7-1-3-11(9(15)5-7)17-12-4-2-8(14)6-10(12)16/h1-6,16H
InChI key
XEFQLINVKFYRCS-UHFFFAOYSA-N
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General description
化学结构式：二苯醚衍生物
Application
一种可能污染动物性食品的人类病原体—耶尔森氏菌的头孢菌素-伊桑-新生物素选择培养基的组成部分。
Biochem/physiol Actions
它是细菌和疟原虫II型脂肪酸合成酶(FAS-II)的烯酰ACP（酰基载体蛋白）还原酶组分的抑制剂。 它还能抑制哺乳动物脂肪酸合成酶（FASN），可能具有抗癌活性。
Other Notes
将容器紧紧地封闭在干燥通风良好的地方。保存在干燥的地方。
signalword
Warning
hcodes
Hazard Classifications
Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Kathleen Dittmann et al.
Antimicrobial resistance and infection control, 8, 122-122 (2019-08-02)
Recent publications have raised concerns of reduced susceptibilities of clinical bacterial isolates towards biocides. This study presents a comparative investigation of the susceptibility of livestock-associated Methicillin-resistant Staphylococcus aureus (LA-MRSA), hospital-acquired MRSA (HA-MRSA) and community-aquired MRSA (CA-MRSA) to the commonly used
Wai Keat Chang et al.
Annals of surgery, 255(5), 854-859 (2012-04-04)
To determine the efficacy and safety of triclosan-impregnated sutures. Surgical-site infections (SSIs) produce considerable morbidity and increase health care costs. A potential strategy to decrease the rates of SSIs may be the use of triclosan-impregnated sutures. These have been endorsed
Joseph V Rodricks et al.
Critical reviews in toxicology, 40(5), 422-484 (2010-04-10)
Triclosan (2,4,4'-trichloro-2'-hydroxy-diphenyl ether) is an antibacterial compound that has been used in consumer products for about 40 years. The tolerability and safety of triclosan has been evaluated in human volunteers with little indication of toxicity or sensitization. Although information in
Markus K Diener et al.
Lancet (London, England), 384(9938), 142-152 (2014-04-11)
Postoperative surgical site infections are one of the most frequent complications after open abdominal surgery, and triclosan-coated sutures were developed to reduce their occurrence. The aim of the PROUD trial was to obtain reliable data for the effectiveness of triclosan-coated
Siamak P Yazdankhah et al.
Microbial drug resistance (Larchmont, N.Y.), 12(2), 83-90 (2006-08-23)
Triclosan is a widely used biocide that is considered as an effective antimicrobial agent against different microorganisms. It is included in many contemporary consumer and personal health-care products, like oral and dermal products, but also in household items, including plastics
商品
Fatty acid synthesis supports cancer cell proliferation, essential for membrane generation, protein modification, and bioenergetics.
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 72779-25G-F | 04061835541744 |
| 72779-5G-F | 04061832862446 |
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