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Merck
CN

72779

三氯生

97.0-103.0% (active substance, GC)

别名:

三氯苯氧氯酚, 5-氯-2-（2,4-二氯苯氧基）苯酚, 氯苯酚

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关于此项目

经验公式（希尔记法）:
C12H7Cl3O2
化学文摘社编号:
3380-34-5
分子量:
289.54
UNSPSC Code:
12352132
NACRES:
NA.85
PubChem Substance ID:
57652433
EC Number:
222-182-2
Beilstein/REAXYS Number:
2057142
MDL number:
MFCD00800992

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产品名称

三氯生, 97.0-103.0% (active substance, GC)

InChI key

XEFQLINVKFYRCS-UHFFFAOYSA-N

InChI

1S/C12H7Cl3O2/c13-7-1-3-11(9(15)5-7)17-12-4-2-8(14)6-10(12)16/h1-6,16H

SMILES string

Oc1cc(Cl)ccc1Oc2ccc(Cl)cc2Cl

biological source

synthetic

assay

97.0-103.0% (active substance, GC)

form

powder or crystals

impurities

≤0.1% Water (Karl Fischer)

color

white

mp

55-59 °C

solubility

1 M NaOH: 5% at 25 °C, faintly turbid to clear (colorless solution)

antibiotic activity spectrum

fungi

mode of action

enzyme | inhibits

Quality Level

200

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相关类别

Application

一种可能污染动物性食品的人类病原体—耶尔森氏菌的头孢菌素-伊桑-新生物素选择培养基的组成部分。

Biochem/physiol Actions

它是细菌和疟原虫II型脂肪酸合成酶(FAS-II)的烯酰ACP（酰基载体蛋白）还原酶组分的抑制剂。 它还能抑制哺乳动物脂肪酸合成酶（FASN），可能具有抗癌活性。

General description

化学结构式：二苯醚衍生物

Other Notes

将容器紧紧地封闭在干燥通风良好的地方。保存在干燥的地方。

pictograms

Exclamation markEnvironment
GHS07,GHS09

signalword

Warning

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2

存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000504464
0000504464
0000485080
0000485080
0000462285

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. What is Product 72779, Irgasan, soluble in?

    Per the chemicals encyclopedia published by the Royal Society of Chemistry, 12th edition, Entry# 9790, Irgasan is not soluble in water, but it is readily soluble in alkaline solutions and many organic solvents.

  4. What are other names besides Irgasan that Product 72779 may be referred to?

    Irgasan may also be referred to as Triclosan and 5-Chloro-2-(2,4-dichlorophenoxy)phenol.

  5. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  6. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  7. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

Cale T Anger et al.
Environmental science & technology, 47(4), 1833-1843 (2013-01-17)
When discharged into surface waters via wastewater effluents, triclosan, the antimicrobial agent in handsoaps, and chlorinated triclosan derivatives (CTDs, formed during disinfection with chlorine) react photochemically to form polychlorinated dibenzo-p-dioxins. To evaluate the historical exposure of waters to these compounds
Kathleen Dittmann et al.
Antimicrobial resistance and infection control, 8, 122-122 (2019-08-02)
Recent publications have raised concerns of reduced susceptibilities of clinical bacterial isolates towards biocides. This study presents a comparative investigation of the susceptibility of livestock-associated Methicillin-resistant Staphylococcus aureus (LA-MRSA), hospital-acquired MRSA (HA-MRSA) and community-aquired MRSA (CA-MRSA) to the commonly used
Markus K Diener et al.
Lancet (London, England), 384(9938), 142-152 (2014-04-11)
Postoperative surgical site infections are one of the most frequent complications after open abdominal surgery, and triclosan-coated sutures were developed to reduce their occurrence. The aim of the PROUD trial was to obtain reliable data for the effectiveness of triclosan-coated
Kannan Krishnan et al.
Regulatory toxicology and pharmacology : RTP, 58(1), 10-17 (2010-06-15)
Recent efforts worldwide have resulted in a growing database of measured concentrations of chemicals in blood and urine samples taken from the general population. However, few tools exist to assist in the interpretation of the measured values in a health
Anthony Blinkhorn et al.
British dental journal, 207(3), 117-125 (2009-08-08)
Dental caries and periodontal disease are the most common oral conditions experienced by adults today. The treatment of these diseases by the dental team can only be performed when patients attend dental practices. There is recognition that the preventive measures
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