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Merck
CN

72964

6-(7-Nitrobenzofurazan-4-ylamino)hexanoic acid

suitable for fluorescence

别名:

6-(7-Nitro-2,1,3-benzoxadiazol-4-ylamino)hexanoic acid

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关于此项目

经验公式（希尔记法）:
C12H14N4O5
化学文摘社编号:
88235-25-0
分子量:
294.26
UNSPSC Code:
12352116
NACRES:
NA.32
PubChem Substance ID:
329764495
MDL number:
MFCD00057884
Beilstein/REAXYS Number:
6936249

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产品名称

6-(7-Nitrobenzofurazan-4-ylamino)hexanoic acid, suitable for fluorescence

InChI

1S/C12H14N4O5/c17-10(18)4-2-1-3-7-13-8-5-6-9(16(19)20)12-11(8)14-21-15-12/h5-6,13H,1-4,7H2,(H,17,18)

SMILES string

OC(=O)CCCCCNc1ccc([N+]([O-])=O)c2nonc12

InChI key

DJFNQJJTTPMBIL-UHFFFAOYSA-N

assay

≥96.0% (HPLC)

form

powder

fluorescence

λex 466 nm; λem 535 nm in methanol

suitability

suitable for fluorescence

Quality Level

100

Other Notes

Probing of the binding sites of fatty acid and sterol carrier proteins

pictograms

Skull and crossbones
GHS06

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCN9488
BCCJ5148
BCCB7529
BCBP5511V
BCBH6218V

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J C McIntyre et al.
Chemistry and physics of lipids, 66(3), 171-180 (1993-12-01)
The synthesis, identification and characterization of neutral lipid analogs containing N-(7-nitro-2,1,3-benzoxadiazoi-4-yl)-aminocaproic acid are reported. The acyl-imidazole derivative of the fluorescent fatty acid was used to esterify L-alpha-glycerophosphorylcholine. Fluorescent phosphatidylcholines were converted to the corresponding diacylglycerols by phospholipase C digestion. Triacylglycerols
A Sofer et al.
Journal of cell science, 109 ( Pt 8), 2111-2119 (1996-08-01)
In order to study the endocytosis of membrane lipids during the development of neuronal polarity, we examined the internalization of a short acyl chain fluorescent derivative of ganglioside GM1, N-(6-(4-nitrobenz-2-oxa-1,3-diazole-7-yl)-aminohexanoyl)-GM1 (C6-NBD-GM1), in hippocampal neurons cultured at low density. C6-NBD-GM1 was
S J Slater et al.
Biochemistry, 32(14), 3714-3721 (1993-04-13)
It is proposed that increased phospholipid unsaturation in membranes and perturbation by agents such as ethanol weaken interlipid hydrogen bonding involving water and that the process is independent of effects on lipid order. To investigate this, the rates of phospholipid
S Lin et al.
Photochemistry and photobiology, 54(3), 361-365 (1991-09-01)
The fluorescence kinetics of the nitrobenzoxadiazole (NBD) chromophore were studied at low concentrations in solvents with varying polarity and hydrogen-bonding donor strength. The emission decay was essentially single exponential in all solvents studied. While the absorption and fluorescence solvatochromism is
D W Dekkers et al.
The Biochemical journal, 350 Pt 2, 531-535 (2000-08-19)
The role of multidrug resistance protein 1 (MRP1) in the maintenance of transbilayer lipid asymmetry in the erythrocyte membrane was investigated. The transbilayer distribution of endogenous phospholipids and [(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino]hexanoyl (NBD)-labelled lipid analogues was compared in the absence and the presence
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