73677
4-硝基苯基 β-D-葡糖苷酸
β-glucuronidase substrate, chromogenic, ≥99.0% (TLC), powder or crystals, suitable as substrate for β-glucuronidase test
别名:
4-硝基苯基-β-D-吡喃葡萄糖醛酸, PNPG
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关于此项目
经验公式（希尔记法）:
C12H13NO9
化学文摘社编号:
分子量:
315.23
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352204
EC Number:
233-753-0
MDL number:
Beilstein/REAXYS Number:
1438576
产品名称
4-硝基苯基 β-D-葡糖苷酸, ≥99.0% (TLC)
InChI key
QSUILVWOWLUOEU-GOVZDWNOSA-N
InChI
1S/C12H13NO9/c14-7-8(15)10(11(17)18)22-12(9(7)16)21-6-3-1-5(2-4-6)13(19)20/h1-4,7-10,12,14-16H,(H,17,18)/t7-,8-,9+,10-,12+/m0/s1
SMILES string
O[C@@H]1[C@@H](O)[C@@H](O[C@@H]([C@H]1O)C(O)=O)Oc2ccc(cc2)[N+]([O-])=O
assay
≥99.0% (TLC)
form
powder or crystals
optical activity
[α]20/D −102±3°, c = 1% in ethanol
impurities
≤0.05% free 4-nitrophenol, ≤7% water
solubility
H2O: 0.1 g/mL, clear, faintly yellow
suitability
suitable as substrate for β-glucuronidase test
storage temp.
−20°C
Quality Level
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General description
用于 β-葡萄糖醛酸酶（GUS）基因检测的显色底物。
Application
4-硝基苯基β-D-葡萄糖醛酸苷用于测定尿液样本中β-葡萄糖醛酸苷酶的活性，盲肠内容物消化物细菌和牛肝中β-葡萄糖醛酸苷酶的活性。 也用来研究苦味叶下珠提取物对β-葡萄糖醛酸苷酶的抑制作用。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Effect of tobacco smoking on albumin concentration and beta-glucuronidase activity in urine of smelters
Bizonn A, et al.
Przegla?d Lekarski, 71(11), 581-584 (2014)
Synthesis of Glycaro-1, 5-lactams and Tetrahydrotetrazolopyridine-5-carboxylates: Inhibitors of beta-D-Glucuronidase and alpha-L-Iduronidase
Pabba J, et al.
Helvetica Chimica Acta, 89(4), 635-666 (2006)
Effect of dietary honey on intestinal microflora and toxicity of mycotoxins in mice
El-Arab AME, et al.
BMC Complementary and Alternative Medicine, 6(1), 6-6 (2006)
Rapid separation of p-nitrophenol and its glucuronide and sulfate conjugates by reversed-phase high-performance liquid chromatography.
G Diamond et al.
Journal of chromatography, 177(2), 368-371 (1979-09-21)
beta-Glucuronidase Inhibitory Effect of Phenolic Constituents from Phyllanthus amarus.
Joshi CS and Sanmuga Priya E
Pharmaceutical biology, 45(5), 363-365 (2007)
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