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Merck
CN

74680

Sigma-Aldrich

八甘醇单十二烷基醚

BioXtra, ≥98.0% (GC)

别名:

C12E8, 八甘醇十二烷基醚, 八甘醇单十二醚, 聚氧乙烯(8)月桂基醚

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关于此项目

线性分子式:
CH3(CH2)11(OCH2CH2)8OH
化学文摘社编号:
分子量:
538.75
Beilstein:
1893466
MDL编号:
UNSPSC代码:
12161900
PubChem化学物质编号:
NACRES:
NA.25
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描述

non-ionic

质量水平

产品线

BioXtra

方案

≥98.0% (GC)

表单

solid

分子量

538.75 g/mol

CMC

0.11

痕量阳离子

Ca: ≤50 mg/kg
Cd: ≤50 mg/kg
Co: ≤50 mg/kg
Cr: ≤50 mg/kg
Cu: ≤50 mg/kg
Fe: ≤50 mg/kg
K: ≤50 mg/kg
Mg: ≤50 mg/kg
Mn: ≤50 mg/kg
Na: ≤50 mg/kg
Ni: ≤50 mg/kg
Pb: ≤50 mg/kg
Zn: ≤50 mg/kg

SMILES字符串

CCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCO

InChI

1S/C28H58O9/c1-2-3-4-5-6-7-8-9-10-11-13-30-15-17-32-19-21-34-23-25-36-27-28-37-26-24-35-22-20-33-18-16-31-14-12-29/h29H,2-28H2,1H3

InChI key

YYELLDKEOUKVIQ-UHFFFAOYSA-N

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一般描述

Octaethylene glycol monododecyl ether is a nonionic detergent.

应用

作为去污剂,用于研究天然样状态的膜蛋白,如 ATP酶。 用于中性pH下脂氧合酶的混合胶束检测以及用于流感病毒包膜的功能性重建。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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L Tortech et al.
Biochimica et biophysica acta, 1514(1), 76-86 (2001-08-22)
Many attempts have been made to rationalize the use of detergents for membrane protein studies [J. Biol. Chem. 264 (1989) 4907]. The barrier properties of the detergent headgroup may be one parameter critically involved in protein protection. In this paper
M Bobrowska-Hägerstrand et al.
Biophysical journal, 77(6), 3356-3362 (1999-12-10)
Endovesicles induced in human erythrocytes by octaethyleneglycol dodecylether (C12E8) were studied by confocal laser scanning microscopy, using fluorescein isothiocyanate dextran as a nonspecific fluid marker. The endovesicles appeared to consist mainly of a ring-formed toroidal part joined with a central
Cédric Montigny et al.
Biochemical and biophysical research communications, 391(1), 1067-1069 (2009-12-17)
Many membrane proteins become labile when they are solubilized by detergent. Here we show that the presence of high concentrations of glycyl betaine stabilizes one of these proteins, the sarcoplasmic reticulum Ca(2+)-ATPase (SERCA1a), solubilized with nonionic detergents like n-dodecyl beta-d-maltopyranoside
[Relationship between activity and tetraprotomeric structure of ion-transporting ATPases].
Kazuhiro Abe et al.
Seikagaku. The Journal of Japanese Biochemical Society, 79(6), 527-534 (2007-08-01)
G C Troiano et al.
Biophysical journal, 75(2), 880-888 (1998-07-24)
The effects of a nonionic surfactant, octaethyleneglycol mono n-dodecyl ether (C12E8), on the electroporation of planar bilayer lipid membranes made of the synthetic lipid 1-pamitoyl 2-oleoyl phosphatidylcholine (POPC), was studied. High-amplitude ( approximately 100-450 mV) rectangular voltage pulses were used

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