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75250

Salvinorin B

Name: Salvinorin B
Brand: SIGMA

≥93.0% (HPLC), κ-opioid DREADD activator, powder or crystals

别名:

, Divinorin B

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关于此项目

经验公式（希尔记法）:

C₂₁H₂₆O₇

化学文摘社编号:

92545-30-7

分子量:

390.43

NACRES:

NA.83

PubChem Substance ID:

329766282

UNSPSC Code:

12352204

MDL number:

MFCD16036232

Beilstein/REAXYS Number:

4335292

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产品名称

Salvinorin B, ≥93.0% (HPLC)

Quality Level

100

assay

≥93.0% (HPLC)

form

powder or crystals

drug control

regulated under CDSA - not available from Sigma-Aldrich Canada

solubility

chloroform: soluble

storage temp.

−20°C

SMILES string

COC(=O)[C@@H]1C[C@H](O)C(=O)[C@H]2[C@@]1(C)CC[C@H]3C(=O)O[C@@H](C[C@]23C)c4ccoc4

InChI

1S/C21H26O7/c1-20-6-4-12-19(25)28-15(11-5-7-27-10-11)9-21(12,2)17(20)16(23)14(22)8-13(20)18(24)26-3/h5,7,10,12-15,17,22H,4,6,8-9H2,1-3H3/t12-,13-,14-,15-,17-,20-,21-/m0/s1

InChI key

BLTMVAIOAAGYAR-CEFSSPBYSA-N

Biochem/physiol Actions

丹酚B 是丹酚A 的主要脱乙酰化代谢产物。丹酚A 是来自 迷幻鼠尾草 的一种二萜，据报告称具有精神活性，但在丹酚B中并未发现。

Packaging

无底玻璃瓶。内含物装在插入式熔锥内。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Determination of salvinorin A and salvinorin B in Salvia divinorum-related products circulated in Japan.

Kenji Tsujikawa et al.

Forensic science international, 180(2-3), 105-109 (2008-09-05)

Two major salvinorins, salvinorin A (SalA) and salvinorin B (SalB), in three Salvia divinorum dried leaf products and nine of its "concentrated extract" products circulated in Japan were determined. These ingredients were extracted twice with acetonitrile and decolored with graphite

Standard protecting groups create potent and selective kappa opioids: salvinorin B alkoxymethyl ethers.

Thomas A Munro et al.

Bioorganic & medicinal chemistry, 16(3), 1279-1286 (2007-11-06)

Protection of salvinorin B as standard alkoxyalkyl ethers yielded highly potent kappa opioid receptor agonists. Ethoxymethyl ether 6 is among the most potent and selective kappa agonists reported to date. Fluoroethoxymethyl ether 11 is the first potent, selective fluorinated kappa

Screening of Hallucinogenic Compounds and Genomic Characterisation of 40 Anatolian Salvia Species.

Seda Damla Hatipoglu et al.

Phytochemical analysis : PCA, 28(6), 541-549 (2017-07-20)

Salvia, an important and widely available member of Lamiaceae family. Although comparative analysis on secondary metabolites in several Salvia species from Turkey has been reported, their hallucinogenic chemicals have not been screened thoroughly. This study provides LC-MS/MS analysis of 40

Medial Amygdala Kiss1 Neurons Mediate Female Pheromone Stimulation of Luteinizing Hormone in Male Mice.

Sanya Aggarwal et al.

Neuroendocrinology, 108(3), 172-189 (2018-12-12)

The medial amygdala (MeA) responds to olfactory stimuli and alters reproductive physiology. However, the neuronal circuit that relays signals from the MeA to the reproductive axis remains poorly defined. This study aimed to test whether MeA kisspeptin (MeAKiss) neurons in

Salvinorin A, an active component of the hallucinogenic sage salvia divinorum is a highly efficacious kappa-opioid receptor agonist: structural and functional considerations.

Charles Chavkin et al.

The Journal of pharmacology and experimental therapeutics, 308(3), 1197-1203 (2004-01-14)

The diterpene salvinorin A from Salvia divinorum has recently been reported to be a high-affinity and selective kappa-opioid receptor agonist (Roth et al., 2002). Salvinorin A and selected derivatives were found to be potent and efficacious agonists in several measures

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全球贸易项目编号

货号	GTIN
75250-1MG	04061825700205
75250-5MG	04061831580136

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