75440
L-鸟氨酸 二盐酸盐
≥99.0% (AT)
别名:
(S)-2,5-二氨基戊酸 二盐酸盐
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关于此项目
经验公式（希尔记法）:
C5H12N2O2 · 2HCl
化学文摘社编号:
分子量:
205.08
UNSPSC Code:
12352209
NACRES:
NA.26
PubChem Substance ID:
EC Number:
228-277-5
Beilstein/REAXYS Number:
4538819
MDL number:
产品名称
L-鸟氨酸 二盐酸盐, ≥99.0% (AT)
InChI key
HGBAVEGDXFHRQP-FHNDMYTFSA-N
InChI
1S/C5H12N2O2.2ClH/c6-3-1-2-4(7)5(8)9;;/h4H,1-3,6-7H2,(H,8,9);2*1H/t4-;;/m0../s1
SMILES string
Cl.Cl.NCCC[C@H](N)C(O)=O
assay
≥99.0% (AT)
form
crystals
optical activity
[α]20/D +17±1°, c = 5% in H2O
technique(s)
ligand binding assay: suitable
ign. residue
≤0.1% (as SO4)
color
colorless
mp
197-199 °C (dec.)
anion traces
sulfate (SO42-): ≤100 mg/kg
cation traces
As: ≤0.1 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
NH4+: ≤100 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg
Biochem/physiol Actions
L-Ornithine is a non-proteinogenic recycled component of the Urea Cycle leading to the production of arginine. L-ornithine is the starting compound for polyamine biosynthesis via ornithine decarboxylase.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Francois Blachier et al.
Frontiers in bioscience (Landmark edition), 16, 1331-1343 (2011-01-05)
Colon epithelium is renewed within few days through asymmetric mitosis of pluripotent cells followed by differentiation and exfoliation. Absorptive colonocytes do not transport amino acids from lumen to bloodstream but import amino acids from plasma. Among amino acids, colonocytes can
V Walker
Diabetes, obesity & metabolism, 11(9), 823-835 (2009-06-18)
The urea cycle is the final pathway for removal of surplus nitrogen from the body, and the major route in humans for detoxification of ammonia. The full complement of enzymes is expressed only in liver. Inherited deficiencies of urea cycle
Jens Schneider et al.
Applied microbiology and biotechnology, 91(1), 17-30 (2011-05-10)
In Bacteria, the pathways of polyamine biosynthesis start with the amino acids L-lysine, L-ornithine, L-arginine, or L-aspartic acid. Some of these polyamines are of special interest due to their use in the production of engineering plastics (e.g., polyamides) or as
Markus Munder
British journal of pharmacology, 158(3), 638-651 (2009-09-22)
The enzyme arginase metabolizes L-arginine to L-ornithine and urea. Besides its fundamental role in the hepatic urea cycle, arginase is also expressed the immune system of mice and man. While significant interspecies differences exist regarding expression, subcellular localization and regulation
M Reimann et al.
Atherosclerosis. Supplements, 14(1), 143-149 (2013-01-30)
The study of small-molecule metabolites may assist in cardiovascular risk monitoring during therapy. We assessed whether acute changes in the metabolome by lipoprotein apheresis are able to predict changes in microvascular function. We performed mass-spectrometry-based profiling of 186 metabolites in
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