76157
(4R)-4-羟基-L-谷氨酸
≥98.0% (TLC)
别名:
erythro-(4R)-4-Hydroxy-L-glutamic acid, H-(2S,4R)-γ-Hydroxy-Glu-OH
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关于此项目
经验公式（希尔记法）:
C5H9NO5
化学文摘社编号:
分子量:
163.13
NACRES:
NA.28
PubChem Substance ID:
UNSPSC Code:
12352202
MDL number:
Beilstein/REAXYS Number:
1725871
产品名称
(4R)-4-羟基-L-谷氨酸, ≥98.0% (TLC)
Quality Segment
assay
≥98.0% (TLC)
form
powder
optical activity
[α]/D 20.5±1.5°, c = 1 in H2O
color
white
mp
171 °C
storage temp.
−20°C
SMILES string
N[C@@H](C[C@@H](O)C(O)=O)C(O)=O
InChI
1S/C5H9NO5/c6-2(4(8)9)1-3(7)5(10)11/h2-3,7H,1,6H2,(H,8,9)(H,10,11)/t2-,3+/m0/s1
InChI key
HBDWQSHEVMSFGY-STHAYSLISA-N
Biochem/physiol Actions
(4R)-4-Hydroxy-L-glutamic acid or (2S,4R)-4-hydroxyglutamate was shown to activate the metabotropic glutamate receptors, mGlu1a, mGlu2, and mGlu8a in a dose-dependent manner.
Substrate for aminotransferase; pharmacological characterization at human glutamate transporter subtypes 1-3; for studying structure-activity relationships (SAR) for ionotropic and metabotropic glutamate receptors.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable