76200
D-泛醇
≥98.0% (NT)
别名:
(R)-(+)-2,4-二羟基-N-(3-羟基丙基)-3,3-二甲基丁酰胺, 右旋泛酰醇, 右旋泛醇, 维生素原 B
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关于此项目
经验公式（希尔记法）:
C9H19NO4
化学文摘社编号:
分子量:
205.25
UNSPSC Code:
12352104
NACRES:
NA.28
PubChem Substance ID:
EC Number:
201-327-3
Beilstein/REAXYS Number:
1724947
MDL number:
biological source
synthetic
Quality Level
assay
≥98.0% (NT)
form
liquid
optical activity
[α]20/D +30±1°, c = 5% in H2O
impurities
≤0.002% heavy metals, ≤0.5% 3-aminopropanol
ign. residue
≤0.1% (as SO4)
color
colorless
refractive index
n20/D 1.496-1.500
density
1.20 g/mL at 20 °C (lit.)
storage temp.
2-8°C
SMILES string
CC(C)(CO)[C@@H](O)C(=O)NCCCO
InChI
1S/C9H19NO4/c1-9(2,6-12)7(13)8(14)10-4-3-5-11/h7,11-13H,3-6H2,1-2H3,(H,10,14)/t7-/m0/s1
InChI key
SNPLKNRPJHDVJA-ZETCQYMHSA-N
Application
- 尿囊素、没药醇、D-泛醇和甘草酸二钾的联用减轻了UVB诱导的角化细胞中PGE（2）的合成: 该研究考察了D-泛醇与其它化合物联用对角化细胞中UVB诱导的炎症的保护作用。 研究结果强调了D-泛醇在皮肤护理配方中的作用，旨在减少紫外线引起的损伤和炎症（Tan et al., 2024）。
- D-泛醇对横纹肌溶解症导致的急性肾损伤的保护作用。: 该研究探讨了D-泛醇在减轻横纹肌溶解症引起的急性肾损伤方面的保护作用。研究结果表明，D-泛醇在肾脏保护和恢复方面有潜在的治疗应用价值（Semenovich et al., 2022）。
- α-甘油磷酰胆碱和D-泛酚滴眼液在白内障手术患者中的应用。: 这项临床研究考察了含D-泛醇滴眼液在接受白内障手术的患者中的疗效，证明了其增强术后恢复和眼睛健康的潜力（Martone et al., 2022）。
- 常见化妆品化合物可以减少空气污染引起的皮肤氧化应激和促炎反应。: 该研究重点关注了D-泛醇保护皮肤免受空气污染引起的氧化应激和炎症的作用，强调了其在城市环境化妆品配方中的重要性（Hergesell et al., 2022）。
Biochem/physiol Actions
D-泛醇是 D-泛酸的醇类似物和生物前体。这些类似物是辅酶 A 生物合成的前体。D-泛醇和 D-泛酸用于各种皮肤保护产品。D-泛酸可能具有控制角质形成细胞增殖和分化的角色。D-泛醇可用于紫外线照射皮肤保护乳剂的研究，也可作为湿润剂。
存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves
X Hui et al.
International journal of cosmetic science, 29(4), 277-282 (2008-05-21)
The in vitro absorption of panthenol into and through the human nail was examined in this study. Panthenol, the alcohol form of pantothenic acid (vitamin B5), is believed to act as a humectant and improve the flexibility and strength of
M Göbbels et al.
Klinische Monatsblatter fur Augenheilkunde, 209(2-3), 84-88 (1996-08-01)
In this controlled, randomized, double-masked study the effect of dexpanthenol-containing artificial tears (Siccaprotect) on patients with dry eyes was examined. 50 patients applied either dexpanthenol-containing artificial tears (Siccaprotect) or the identical, but free of dexpanthenol, eye drops five times daily
M Sachs et al.
Zeitschrift fur Ernahrungswissenschaft, 29(4), 270-283 (1990-12-01)
The aim of this study was the examination of the metabolism and mechanism of action of D-pantothenyl alcohol in patients with postoperative intestinal atony. Seven metabolically healthy patients were examined on the 4th day following colorectal surgery, before bowel activity
Fritz Ebner et al.
American journal of clinical dermatology, 3(6), 427-433 (2002-07-13)
Pantothenic acid is essential to normal epithelial function. It is a component of coenzyme A, which serves as a cofactor for a variety of enzyme-catalyzed reactions that are important in the metabolism of carbohydrates, fatty acids, proteins, gluconeogenesis, sterols, steroid
C F Zanatta et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 48(1), 70-75 (2009-09-22)
Considering the belief that natural lipids are safer for topical applications and that carotenoids are able to protect cells against photooxidative damage, we have investigated whether topical creams and lotions, produced with Buriti oil and commercial surfactants, can exert photoprotective
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 76200-100ML | 04061832919201 |
| 76200-25ML | 04061832919324 |
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