76437
五甘醇单十二烷基醚
BioXtra, ≥98.0% (GC)
别名:
C12E5, 十二烷基五乙二醇醚, 十二烷基五甘醇, 聚氧乙烯(5)月桂基醚
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关于此项目
线性分子式:
CH3(CH2)11(OCH2CH2)5OH
化学文摘社编号:
分子量:
406.60
Beilstein:
1797921
EC 号:
MDL编号:
UNSPSC代码:
12161900
PubChem化学物质编号:
NACRES:
NA.25
描述
non-ionic
质量水平
产品线
BioXtra
方案
≥98.0% (GC)
表单
semisolid
分子量
406.60 g/mol
技术
drug transporter assay: suitable
密度
0.963 g/mL at 20 °C (lit.)
痕量阳离子
Ca: ≤50 mg/kg
Cd: ≤50 mg/kg
Co: ≤50 mg/kg
Cr: ≤50 mg/kg
Cu: ≤50 mg/kg
Fe: ≤50 mg/kg
K: ≤50 mg/kg
Mg: ≤50 mg/kg
Mn: ≤50 mg/kg
Na: ≤50 mg/kg
Ni: ≤50 mg/kg
Pb: ≤50 mg/kg
Zn: ≤50 mg/kg
SMILES字符串
CCCCCCCCCCCCOCCOCCOCCOCCOCCO
InChI
1S/C22H46O6/c1-2-3-4-5-6-7-8-9-10-11-13-24-15-17-26-19-21-28-22-20-27-18-16-25-14-12-23/h23H,2-22H2,1H3
InChI key
LAPRIVJANDLWOK-UHFFFAOYSA-N
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应用
<ul>
<li><strong>单克隆抗体和非离子表面活性剂在SiO(2)/水界面上的共吸附：</strong>本研究证明了五乙二醇单十二烷基醚与单克隆抗体的共吸附特性，对于生物制药制剂提高药物稳定性和递送具有重要意义（Lu et al., 2018）。</li>
<li><strong>使用水溶性表面活性剂添加剂对疏水性聚合物进行防水表面改性：</strong>本研究表明，五乙二醇单十二烷基醚能够对疏水性聚合物表面进行改性，使其具有防水性，指出了其在各种工业和涂料应用中的实用性（Thompson et al., 2021）。</li>
<li><strong>温度和盐度在非离子表面活性剂包覆二氧化硅纳米颗粒聚集中的协同作用：</strong>重点介绍了五乙二醇单十二烷基醚在纳米颗粒稳定方面的应用，特别是在不同的温度和盐度条件下，有助于定制药物递送系统和环境应用（Bharti et al., 2023）。</li>
</ul>
<li><strong>单克隆抗体和非离子表面活性剂在SiO(2)/水界面上的共吸附：</strong>本研究证明了五乙二醇单十二烷基醚与单克隆抗体的共吸附特性，对于生物制药制剂提高药物稳定性和递送具有重要意义（Lu et al., 2018）。</li>
<li><strong>使用水溶性表面活性剂添加剂对疏水性聚合物进行防水表面改性：</strong>本研究表明，五乙二醇单十二烷基醚能够对疏水性聚合物表面进行改性，使其具有防水性，指出了其在各种工业和涂料应用中的实用性（Thompson et al., 2021）。</li>
<li><strong>温度和盐度在非离子表面活性剂包覆二氧化硅纳米颗粒聚集中的协同作用：</strong>重点介绍了五乙二醇单十二烷基醚在纳米颗粒稳定方面的应用，特别是在不同的温度和盐度条件下，有助于定制药物递送系统和环境应用（Bharti et al., 2023）。</li>
</ul>
警示用语：
Danger
危险声明
危险分类
Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
10 - Combustible liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
H Pfeiffer et al.
Chemistry and physics of lipids, 139(1), 54-67 (2005-11-19)
The present paper reports on the phase behaviour of the pseudobinary aqueous mixtures of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC)/pentaethylene glycol monododecyl ether (C12E5) and 1,2-dimyristoyl-sn-glycero-3-phosphocholine monohydrate (DMPC)/C12E5. Both systems exhibit a variety of mesophases, such as lamellar gel, liquid crystalline and micellar phases.
Maria Velinova et al.
Langmuir : the ACS journal of surfaces and colloids, 27(23), 14071-14077 (2011-10-11)
Control of the size and agglomeration of micellar systems is important for pharmaceutical applications such as drug delivery. Although shape-related transitions in surfactant solutions are studied experimentally, their molecular mechanisms are still not well understood. In this study, we use
Su Yong Kwon et al.
Physical review letters, 89(25), 258302-258302 (2002-12-18)
We have studied the topological transition of the nonionic micelles of a penta-ethyleneglycol mono n-dodecyl ether (C12E5)/DL-alpha-phosphatidylcholine Dimyristoyl (DMPC) mixture in water by light scattering and viscosity measurements. The topological transition concentration decreases with an increase of the mixing ratio
D Sato et al.
The Journal of membrane biology, 196(1), 33-39 (2004-01-16)
At 0 to 20 degrees C, the Ca(2+)-ATPase activity of the scallop sarcoplasmic reticulum (SR) was observed to be 7-60% of the peak activity at 30 degrees C, while the ATPase activity of the rabbit SR was 0-7% of its
Tiago Mendes Ferreira et al.
Physical chemistry chemical physics : PCCP, 10(39), 6033-6038 (2008-10-01)
A lyotropic nonionic lamellar system composed of pentaethyleneglycol mono n-dodecyl ether and D(2)O was studied using natural abundance (13)C NMR under magic-angle spinning. Applying a two-dimensional recoupling method proposed by Dvinskikh (R-PDLF), (1)H-(13)C dipolar couplings were estimated over a range
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