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Merck
CN

76437

五甘醇单十二烷基醚

BioXtra, ≥98.0% (GC)

别名:

C12E5, 十二烷基五乙二醇醚, 十二烷基五甘醇, 聚氧乙烯(5)月桂基醚

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关于此项目

线性分子式:
CH3(CH2)11(OCH2CH2)5OH
化学文摘社编号:
3055-95-6
分子量:
406.60
UNSPSC Code:
12161900
NACRES:
NA.25
PubChem Substance ID:
57652637
EC Number:
221-281-8
Beilstein/REAXYS Number:
1797921
MDL number:
MFCD00043064

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产品名称

五甘醇单十二烷基醚, BioXtra, ≥98.0% (GC)

InChI key

LAPRIVJANDLWOK-UHFFFAOYSA-N

InChI

1S/C22H46O6/c1-2-3-4-5-6-7-8-9-10-11-13-24-15-17-26-19-21-28-22-20-27-18-16-25-14-12-23/h23H,2-22H2,1H3

SMILES string

CCCCCCCCCCCCOCCOCCOCCOCCOCCO

description

non-ionic

product line

BioXtra

assay

≥98.0% (GC)

form

semisolid

mol wt

406.60 g/mol

technique(s)

drug transporter assay: suitable

density

0.963 g/mL at 20 °C (lit.)

cation traces

Ca: ≤50 mg/kg
Cd: ≤50 mg/kg
Co: ≤50 mg/kg
Cr: ≤50 mg/kg
Cu: ≤50 mg/kg
Fe: ≤50 mg/kg
K: ≤50 mg/kg
Mg: ≤50 mg/kg
Mn: ≤50 mg/kg
Na: ≤50 mg/kg
Ni: ≤50 mg/kg
Pb: ≤50 mg/kg
Zn: ≤50 mg/kg

Quality Level

100

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相关类别

Application

<ul>
<li><strong>单克隆抗体和非离子表面活性剂在SiO(2)/水界面上的共吸附：</strong>本研究证明了五乙二醇单十二烷基醚与单克隆抗体的共吸附特性，对于生物制药制剂提高药物稳定性和递送具有重要意义（Lu et al., 2018）。</li>
<li><strong>使用水溶性表面活性剂添加剂对疏水性聚合物进行防水表面改性：</strong>本研究表明，五乙二醇单十二烷基醚能够对疏水性聚合物表面进行改性，使其具有防水性，指出了其在各种工业和涂料应用中的实用性（Thompson et al., 2021）。</li>
<li><strong>温度和盐度在非离子表面活性剂包覆二氧化硅纳米颗粒聚集中的协同作用：</strong>重点介绍了五乙二醇单十二烷基醚在纳米颗粒稳定方面的应用，特别是在不同的温度和盐度条件下，有助于定制药物递送系统和环境应用（Bharti et al., 2023）。</li>
</ul>

pictograms

CorrosionExclamation mark
GHS05,GHS07

signalword

Danger

Hazard Classifications

Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCJ8328
BCCG3187
BCBW6635
BCBR1720V
BCBN3596V

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Su Yong Kwon et al.
Physical review letters, 89(25), 258302-258302 (2002-12-18)
We have studied the topological transition of the nonionic micelles of a penta-ethyleneglycol mono n-dodecyl ether (C12E5)/DL-alpha-phosphatidylcholine Dimyristoyl (DMPC) mixture in water by light scattering and viscosity measurements. The topological transition concentration decreases with an increase of the mixing ratio
H Pfeiffer et al.
Chemistry and physics of lipids, 139(1), 54-67 (2005-11-19)
The present paper reports on the phase behaviour of the pseudobinary aqueous mixtures of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC)/pentaethylene glycol monododecyl ether (C12E5) and 1,2-dimyristoyl-sn-glycero-3-phosphocholine monohydrate (DMPC)/C12E5. Both systems exhibit a variety of mesophases, such as lamellar gel, liquid crystalline and micellar phases.
Maria Velinova et al.
Langmuir : the ACS journal of surfaces and colloids, 27(23), 14071-14077 (2011-10-11)
Control of the size and agglomeration of micellar systems is important for pharmaceutical applications such as drug delivery. Although shape-related transitions in surfactant solutions are studied experimentally, their molecular mechanisms are still not well understood. In this study, we use
Anna Bodin et al.
Chemical research in toxicology, 16(5), 575-582 (2003-05-21)
Ethoxylated alcohols, widely used as surfactants, are known to be susceptible to oxidation when exposed to air. At autoxidation, a complex mixture is formed, in which alkyl poly(ethylene glycol) aldehydes, alkyl poly(ethylene glycol) formates, hydroxyaldehydes, and formaldehyde have previously been
Y Kawabata et al.
The Journal of chemical physics, 147(3), 034905-034905 (2017-07-25)
Shear-induced multilamellar vesicle (MLV) formation has been studied by coupling the small-angle neutron scattering (SANS) technique with neutron spin echo (NSE) spectroscopy. A 10% mass fraction of the nonionic surfactant pentaethylene glycol dodecyl ether (C
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