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经验公式(希尔记法):
C6H10Li4O10P2
化学文摘社编号:
分子量:
331.85
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352106
MDL number:
InChI
1S/C6H14O10P2.4Li/c1-6(9,4-5(7)8)2-3-15-18(13,14)16-17(10,11)12;;;;/h9H,2-4H2,1H3,(H,7,8)(H,13,14)(H2,10,11,12);;;;/q;4*+1/p-4/t6-;;;;/m1..../s1
SMILES string
[Li+].[Li+].[Li+].[Li+].C[C@@](O)(CCOP([O-])(=O)OP([O-])([O-])=O)CC([O-])=O
InChI key
GFIXUUFXTAPBAD-CZNRRTBNSA-J
assay
≥95% (TLC)
form
powder
optical activity
[α]/D -2.9±0.5°, c = 1 in hydrochloric acid (0.02 M)
storage temp.
−20°C
Quality Level
相关类别
Biochem/physiol Actions
甲羟戊酸途径的代谢产物,在甾醇、多萜醇、血红素和泛醌的生物合成中起关键作用。在疾病肿瘤、自身免疫性疾病、动脉粥样硬化和阿尔茨海默病,以及遗传缺陷的甲羟戊酸激酶等研究领域受到关注。
Packaging
无底玻璃瓶。内含物装在锥底内插管中。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Jonathan Lombard et al.
Molecular biology and evolution, 28(1), 87-99 (2010-07-24)
Isoprenoids are a very diverse family of organic compounds widespread in the three domains of life. Although they are produced from the condensation of the same precursors in all organisms (isopentenyl pyrophosphate and dimethylallyl diphosphate), the evolutionary origin of their
D McCaskill et al.
Analytical biochemistry, 215(1), 142-149 (1993-11-15)
Procedures for the isolation and analysis of all 11 intermediates of the mevalonic acid pathway from acetyl-CoA through geranylgeranyl pyrophosphate were developed. Both acid-labile and base-labile metabolites are simultaneously extracted with good recoveries into 7 M urea at neutral pH
Rik van der Kant et al.
Cell stem cell, 24(3), 363-375 (2019-01-29)
Genetic, epidemiologic, and biochemical evidence suggests that predisposition to Alzheimer's disease (AD) may arise from altered cholesterol metabolism, although the molecular pathways that may link cholesterol to AD phenotypes are only partially understood. Here, we perform a phenotypic screen for
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