产品名称
Atto 425叠氮化物, suitable for fluorescence
InChI
1S/C30H43N5O8/c1-5-42-28(37)24-18-22-17-23-21(2)20-30(3,4)35(25(23)19-26(22)43-29(24)38)10-6-7-27(36)32-8-11-39-13-15-41-16-14-40-12-9-33-34-31/h17-19,21H,5-16,20H2,1-4H3,(H,32,36)
InChI key
RSOCGOAHHWBJFE-UHFFFAOYSA-N
SMILES string
CC(CC(C)(C)N1CCCC(NCCOCCOCCOCCN=[N+]=[N-])=O)C(C1=C2)=CC3=C2OC(C(C(OCC)=O)=C3)=O
assay
≥80.0% (HPCE)
form
solid
manufacturer/tradename
ATTO-TEC GmbH
fluorescence
λex 436 nm; λem 484 nm±10 nm in PBS, pH 7.4
suitability
suitable for fluorescence
storage temp.
−20°C
General description
Atto 425是一种具有香豆素结构的荧光标记物。该染料预期用于生命科学领域，如标记DNA、RNA或蛋白质等。标记物的特征是吸收性强、荧光量子产量高、斯托克斯位移大、光稳定性良好和分子量低。
Atto 425具有中等亲水性。它的荧光可以在405-455 nm范围内有效激发。
叠氮化物修饰适用于与炔烃基团的反应（Huisgen反应 - “点击化学”）。
在此处查找更多信息
Atto 425具有中等亲水性。它的荧光可以在405-455 nm范围内有效激发。
叠氮化物修饰适用于与炔烃基团的反应（Huisgen反应 - “点击化学”）。
在此处查找更多信息
Legal Information
本品仅供研究使用。如果打算商业化，请联系知识产权持有者（德国ATTO-TEC GmbH公司）申请许可。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Katrin G Heinze et al.
Biophysical journal, 86(1 Pt 1), 506-516 (2003-12-26)
Confocal fluorescence spectroscopy is a versatile method for studying dynamics and interactions of biomolecules in their native environment with minimal interference with the observed system. Analyzing coincident fluctuations induced by single molecule movement in spectrally distinct detection channels, dual-color fluorescence
Triple FRET: a tool for studying long-range molecular interactions.
Elke Haustein et al.
Chemphyschem : a European journal of chemical physics and physical chemistry, 4(7), 745-748 (2003-08-07)
Anna I Sulatskaya et al.
The journal of physical chemistry. B, 116(8), 2538-2544 (2012-01-25)
Benzothiazole dye thioflavin T (ThT) is a sensitive probe for amyloid fibril detection. The ThT probing is based on its unique ability to form highly fluorescent complexes with amyloid and amyloid-like fibrils. In this work we propose an approach of
Anna I Sulatskaya et al.
The journal of physical chemistry. B, 115(39), 11519-11524 (2011-08-26)
The fluorescence of the benzothiazole dye thioflavin T (ThT) is a well-known test for amyloid fibril formation. It has now become evident that ThT can also be used for structural investigations of amyloid fibrils and even for the treatment of
Richard S Agnes et al.
Journal of the American Chemical Society, 132(17), 6075-6080 (2010-04-13)
A fluorescent sensor of protein kinase activity has been developed and used to characterize the compartmentalized location of cAMP-dependent protein kinase activity in mitochondria. The sensor functions via a phosphorylation-induced release of a quencher from a peptide-based substrate, producing a
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