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Merck
CN

78948

Atto 425叠氮化物

suitable for fluorescence

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关于此项目

经验公式(希尔记法):
C30H43N5O8
分子量:
601.69
PubChem Substance ID:
UNSPSC Code:
12352200
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InChI

1S/C30H43N5O8/c1-5-42-28(37)24-18-22-17-23-21(2)20-30(3,4)35(25(23)19-26(22)43-29(24)38)10-6-7-27(36)32-8-11-39-13-15-41-16-14-40-12-9-33-34-31/h17-19,21H,5-16,20H2,1-4H3,(H,32,36)

InChI key

RSOCGOAHHWBJFE-UHFFFAOYSA-N

SMILES string

CC(CC(C)(C)N1CCCC(NCCOCCOCCOCCN=[N+]=[N-])=O)C(C1=C2)=CC3=C2OC(C(C(OCC)=O)=C3)=O

assay

≥80.0% (HPCE)

form

solid

manufacturer/tradename

ATTO-TEC GmbH

fluorescence

λex 436 nm; λem 484 nm±10 nm in PBS, pH 7.4

suitability

suitable for fluorescence

storage temp.

−20°C

General description

Atto 425是一种具有香豆素结构的荧光标记物。该染料预期用于生命科学领域,如标记DNA、RNA或蛋白质等。标记物的特征是吸收性强、荧光量子产量高、斯托克斯位移大、光稳定性良好和分子量低。
Atto 425具有中等亲水性。它的荧光可以在405-455 nm范围内有效激发。
叠氮化物修饰适用于与炔烃基团的反应(Huisgen反应 - “点击化学”)。

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Legal Information

本品仅供研究使用。如果打算商业化,请联系知识产权持有者(德国ATTO-TEC GmbH公司)申请许可。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Frequency domain fluorescence microspectrometry: Application to cellular uptake and drug distribution.
Praus, P., et al.
Spectroscopy: An International Journal, 24, 303-307 (2010)
Anna I Sulatskaya et al.
The journal of physical chemistry. B, 115(39), 11519-11524 (2011-08-26)
The fluorescence of the benzothiazole dye thioflavin T (ThT) is a well-known test for amyloid fibril formation. It has now become evident that ThT can also be used for structural investigations of amyloid fibrils and even for the treatment of
Richard S Agnes et al.
Journal of the American Chemical Society, 132(17), 6075-6080 (2010-04-13)
A fluorescent sensor of protein kinase activity has been developed and used to characterize the compartmentalized location of cAMP-dependent protein kinase activity in mitochondria. The sensor functions via a phosphorylation-induced release of a quencher from a peptide-based substrate, producing a
Nermin Seda Kehr et al.
Nanoscale, 2(4), 601-605 (2010-07-21)
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Triple FRET: a tool for studying long-range molecular interactions.
Elke Haustein et al.
Chemphyschem : a European journal of chemical physics and physical chemistry, 4(7), 745-748 (2003-08-07)

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