Quality Level
assay
95% (TLC)
form
powder or crystals
relevant disease(s)
Alzheimer′s disease; autoimmune diseases
storage temp.
2-8°C
SMILES string
OC(CC(C)(O)CCOP(O)(O)=O)=O.[H]O[H].[Li+]
InChI
1S/C6H13O7P.3Li.H2O/c1-6(9,4-5(7)8)2-3-13-14(10,11)12;;;;/h9H,2-4H2,1H3,(H,7,8)(H2,10,11,12);;;;1H2/q;3*+1;/p-3
InChI key
VYTYNAKRCDFACM-UHFFFAOYSA-K
Biochem/physiol Actions
甲羟戊酸途径的代谢产物，在甾醇、多萜醇、血红素和泛醌的生物合成中起关键作用。对肿瘤学、自身免疫性疾病、动脉粥样硬化和阿尔茨海默病等疾病领域的研究以及甲羟戊酸激酶的遗传缺陷感兴趣。
Packaging
无底玻璃瓶。内容物在插入式融锥内。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Inhibition of hepatic cholesterol biosynthesis by 3,5-dihydroxy-3,4,4-trimethylvaleric acid and its site of action.
F H Hulcher
Archives of biochemistry and biophysics, 146(2), 422-427 (1971-10-01)
John L Andreassi et al.
Biochemistry, 48(27), 6461-6468 (2009-06-03)
The galacto-, homoserine-, mevalonate-, phosphomevalonate-kinase (GHMP) superfamily encompases a wide-range of protein function. Three members of the family (mevalonate kinase, phosphomevalonate kinase, and diphosphomevalonate decarboxylase) comprise the mevalonate pathway found in S. pneumoniae and other organisms. We have determined the
Li Gong et al.
Cell death & disease, 10(4), 327-327 (2019-04-13)
The mevalonate pathway is known for the synthesis of cholesterol, but recent studies have reported that it also controls Hippo signaling, which is critical for the regulation of organ size and tumorigenesis. Here, we discover that the suppression of the
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| C2175-.5MG | 04061832676302 |
| C2175-5MG | 04061832676326 |
| C2175-250UG | 04061832676319 |
| C2175-1MG | 04061833475270 |
| 79849-50MG | 04061832966588 |
| 79849-10MG | 04061832386027 |