80198
吡咯喹啉醌酸 二钠盐
≥97.0% (HPLC)
别名:
PQQ, 吡咯喹啉醌 二钠盐
登录 查看组织和合同定价。
选择尺寸
变更视图
关于此项目
经验公式（希尔记法）:
C14H4N2Na2O8
化学文摘社编号:
分子量:
374.17
NACRES:
NA.79
PubChem Substance ID:
UNSPSC Code:
12352005
MDL number:
biological source
fermentation/recombinant
Quality Level
assay
≥97.0% (HPLC)
form
powder
color
red-brown to deep orange, red-brown to deep red-brown
storage temp.
2-8°C
SMILES string
OC(=O)c1cc(nc2C(=O)C(=O)c3cc([nH]c3-c12)C(=O)O[Na])C(=O)O[Na]
InChI
1S/C14H6N2O8.2Na/c17-10-4-2-6(14(23)24)15-8(4)7-3(12(19)20)1-5(13(21)22)16-9(7)11(10)18;;/h1-2,15H,(H,19,20)(H,21,22)(H,23,24);;/q;2*+1/p-2
InChI key
UFVBOGYDCJNLPM-UHFFFAOYSA-L
General description
吡咯喹啉醌（PQQ）最常见于植物、少数几种细菌和单细胞真核生物（如酵母）。它主要从甲基营养型细菌中获取。PQQ也存在于哺乳动物组织中。
Application
- 新型膳食吡咯并喹啉醌二钠盐（mnemoPQQ）的安全性评估：本研究考察了吡咯并喹啉醌的安全性，这对其在临床和诊断检测开发中的应用有一定影响。具体而言，它解决了膳食补充剂中所用化合物的问题，并可能涉及对安全性和毒性有最高要求的临床试验（Shiojima et al., 2022）。
Biochem/physiol Actions
在细菌中，吡咯喹啉醌（PQQ）用作氧化还原循环辅因子。它也可以作为辅因子（辅基）参与葡萄糖和甲醇脱氢酶的酶催化氧化还原反应。PQQ可在脂质体中用于建立简单的均相测定，从而通过抗微生物肽和合成共聚物对膜的通透化进行检测。在牛血浆胺氧化酶中，吡咯喹啉醌可作为辅因子。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Mohamed Alburaki et al.
PloS one, 10(5), e0125790-e0125790 (2015-05-21)
Thirty-two honeybee (Apis mellifera) colonies were studied in order to detect and measure potential in vivo effects of neonicotinoid pesticides used in cornfields (Zea mays spp) on honeybee health. Honeybee colonies were randomly split on four different agricultural cornfield areas
Lingbo Kong et al.
PloS one, 8(4), e61013-e61013 (2013-04-25)
The effects of pyrroloquinoline quinine (PQQ) on RANKL-induced osteoclast differentiation and on wear particle-induced osteolysis were examined in this study. PQQ inhibited RANKL-mediated osteoclast differentiation in bone marrow macrophages (BMMs) in a dose-dependent manner without any evidence of cytotoxicity. The
Pyrroloquinoline Quinone: Its Profile, Effects on the Liver and Implications for Health and Disease Prevention
Dietary Interventions in Liver Disease, 157-173 (2019)
Chee-Hoe Ng et al.
Neurobiology of aging, 55, 33-37 (2017-04-14)
Despite intensive research, the etiology of Parkinson's disease (PD) remains poorly understood and the disease remains incurable. However, compelling evidence gathered over decades of research strongly support a role for mitochondrial dysfunction in PD pathogenesis. Related to this, PGC-1α, a
Absorbance-based assay for membrane disruption by antimicrobial peptides and synthetic copolymers using pyrroloquinoline quinone-loaded liposomes
Zimmerman LB, et al.
Analytical biochemistry, 411(2), 194-199 (2011)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 80198-10MG-F | 04061833491218 |
| 80198-50MG-F | 04061833417805 |
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持