81349
聚(2′-脱氧肌苷-2′-脱氧胞苷酸) 钠盐
powder
别名:
聚(dI-dC) 钠盐
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关于此项目
Form:
powder
Solubility:
water: 1 mL/vial, clear, colorless
Storage temp.:
−20°C
产品名称
聚(2′-脱氧肌苷-2′-脱氧胞苷酸) 钠盐, free from low molecular weight nucleotides, lyophilized
solubility
water: 1 mL/vial, clear, colorless
grade
Molecular Biology
form
powder
quality
lyophilized
mol wt
Mr ~2.5 × 106 (broad molecular weight distribution), Mr ~2500000
packaging
ampule of ≥10 units A260
storage temp.
−20°C
Quality Level
General description
聚（2′-脱氧肌苷-2′-脱氧胞苷酸）钠盐是一种交替共聚物，其可作为DNA甲基转移酶的底物。
Application
聚(2′-脱氧肌苷-2′-脱氧胞苷酸) 钠盐已被用于转录因子AP-2 Alpha (TFAP2A)的电泳迁移率变动分析(EMSA)，以及人胚胎肾细胞(HEK293)核提取物的Southwestern印迹中。
适用于
- EMSA中的非特异性阻断剂
- DNA甲基转移酶的评估
- DNA-小分子或药物相互作用研究
Biochem/physiol Actions
聚(2′-脱氧肌苷-2′-脱氧胞苷酸)，聚(dI-dC)是一种合成的DNA底物。 在高盐下，聚(dI-dC)以左旋螺旋构象存在，并在减少盐浓度过程中恢复为右旋形式。 它在电泳迁移率变动分析(EMSA)中可用作非特异性竞争剂。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Xiaomei Xu et al.
eLife, 9 (2020-08-09)
Local activation and long-range inhibition are mechanisms conserved in self-organizing systems leading to biological patterns. A number of them involve the production by the developing cell of an inhibitory morphogen, but how this cell becomes immune to self-inhibition is rather
An enzymatic method for the determination of dCTP and dGTP in picomole amounts.
L Skoog
European journal of biochemistry, 17(2), 202-208 (1970-12-01)
TFAP2A is a component of the ZEB1/2 network that regulates TGFB1-induced epithelial to mesenchymal transition
Dimitrova Y, et al.
Biology Direct, 12(1), 8-8 (2017)
Repeated probing of Southwestern blots using alkaline phosphatase stripping
Jia Y, et al.
Journal of Chromatography A, 1217(45), 7177-7181 (2010)
Helical nature of poly (dl-dC). poly (dl-dC). Vibrational circular dichroism results
Wang L and Keiderling TA
Nucleic Acids Research, 21(17), 4127-4132 (1993)
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