81838
L-C-炔丙基甘氨酸
≥99.0% (TLC)
别名:
L-炔丙基甘氨酸, (S)-2-氨基-4-戊炔酸
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关于此项目
经验公式（希尔记法）:
C5H7NO2
化学文摘社编号:
分子量:
113.11
Beilstein:
2347861
MDL编号:
UNSPSC代码:
12352209
eCl@ss:
32160406
PubChem化学物质编号:
NACRES:
NA.26
产品名称
L-C-炔丙基甘氨酸, ≥99.0% (TLC)
质量水平
方案
≥99.0% (TLC)
表单
powder
颜色
white
mp
235-239 °C
应用
peptide synthesis
储存温度
2-8°C
SMILES字符串
N[C@@H](CC#C)C(O)=O
InChI
1S/C5H7NO2/c1-2-3-4(6)5(7)8/h1,4H,3,6H2,(H,7,8)/t4-/m0/s1
InChI key
DGYHPLMPMRKMPD-BYPYZUCNSA-N
应用
用于 γ-胱硫醚酶不可逆失活的试剂；γ-胱硫醚酶和其他酶的亲和标记试剂；含有该氨基酸的肽可以被氚化至高比放射性
生化/生理作用
L-炔丙基甘氨酸（PAG）是胱硫醚 γ-裂解酶（CSE）的抑制剂，可用于研究硫化氢的合成和生物活性。
L-炔丙基甘酸是一种特异性的 H（2）S 合酶胱硫醚-γ-裂解酶（CSE）的抑制剂，可用于研究 H2S 在生物学过程调节中的作用。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
Bridget Fox et al.
Journal of cellular and molecular medicine, 16(4), 896-910 (2011-06-18)
Hydrogen sulfide (H(2)S) has recently been proposed as an endogenous mediator of inflammation and is present in human synovial fluid. This study determined whether primary human articular chondrocytes (HACs) and mesenchymal progenitor cells (MPCs) could synthesize H(2)S in response to
Shiau Wei Lee et al.
Glia, 54(2), 116-124 (2006-05-24)
Hydrogen sulphide (H2S), which is produced endogenously from L-cysteine in mammalian tissues, has been suggested to function as a neuromodulator in the brain. However, the role of H2S in microglial cells is unclear. In this study, the effect of exogenous
A.N. Eberle et al.
Helvetica Chimica Acta, 68, 1880-1880 (1985)
Mechanism of inactivation of gamma-cystathionase by the acetylenic substrate analogue propargylglycine.
W Washtien et al.
Biochemistry, 16(11), 2485-2491 (1977-05-31)
Metabolic consequences of affinity labeling of cystathionase and alanine aminotransferase by L-propargylglycine in vivo.
S Shinozuka et al.
European journal of biochemistry, 124(2), 377-382 (1982-05-17)
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