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Merck
CN

81838

L-C-炔丙基甘氨酸

≥99.0% (TLC)

别名:

L-炔丙基甘氨酸, (S)-2-氨基-4-戊炔酸

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关于此项目

经验公式(希尔记法):
C5H7NO2
化学文摘社编号:
分子量:
113.11
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26
Beilstein/REAXYS Number:
2347861
MDL number:
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产品名称

L-C-炔丙基甘氨酸, ≥99.0% (TLC)

SMILES string

N[C@@H](CC#C)C(O)=O

InChI

1S/C5H7NO2/c1-2-3-4(6)5(7)8/h1,4H,3,6H2,(H,7,8)/t4-/m0/s1

InChI key

DGYHPLMPMRKMPD-BYPYZUCNSA-N

assay

≥99.0% (TLC)

form

powder

color

white

mp

235-239 °C

application(s)

peptide synthesis

storage temp.

2-8°C

Quality Level

Application

用于 γ-胱硫醚酶不可逆失活的试剂;γ-胱硫醚酶和其他酶的亲和标记试剂;含有该氨基酸的肽可以被氚化至高比放射性

Biochem/physiol Actions

L-炔丙基甘氨酸(PAG)是胱硫醚 γ-裂解酶(CSE)的抑制剂,可用于研究硫化氢的合成和生物活性。
L-炔丙基甘酸是一种特异性的 H(2)S 合酶胱硫醚-γ-裂解酶(CSE)的抑制剂,可用于研究 H2S 在生物学过程调节中的作用。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

新产品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Bridget Fox et al.
Journal of cellular and molecular medicine, 16(4), 896-910 (2011-06-18)
Hydrogen sulfide (H(2)S) has recently been proposed as an endogenous mediator of inflammation and is present in human synovial fluid. This study determined whether primary human articular chondrocytes (HACs) and mesenchymal progenitor cells (MPCs) could synthesize H(2)S in response to
K Sasaki et al.
Biochemistry international, 10(2), 165-175 (1985-02-01)
Cystathionine accumulated in several tissues of dams and fetuses by a single intraperitoneal administration of L-proparglyglycine to pregnant rats. Cystathionine in the liver of dams reached its maximal level at about 15 hrs after L-proparglyglycine injection (10 mg/300g), while that
V Gil et al.
British journal of pharmacology, 164(2b), 485-498 (2011-04-14)
The role of hydrogen sulphide (H₂S) as a putative endogenous signalling molecule in the gastrointestinal tract has not yet been established. We investigated the effect of D,L-propargylglycine (PAG), an inhibitor of cystathionine γ-lyase (CSE), amino-oxyacetic acid (AOAA) and hydroxylamine (HA)
Yan Gao et al.
International journal of cardiology, 152(2), 177-183 (2011-02-15)
Hydrogen sulfide (H(2)S) displays anti-inflammatory and cytoprotective activities to attenuate myocardial ischemia-reperfusion (MIR)-induced injury, but its role in MIR in diabetics is not known. This study was undertaken to investigate whether H(2)S plays a protective role in MIR in diabetic
Emanuela Pupo et al.
Free radical biology & medicine, 51(9), 1765-1773 (2011-08-31)
Hydrogen sulfide (H(2)S) is a gasotransmitter that plays several roles in various tissues, including the cardiovascular system. Because it has been recently proposed to act as a mediator of angiogenesis progression, here we investigate the effects of H(2)S in a

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