82435
葛根素
≥98.0% (HPLC)
别名:
8-(β-D-吡喃葡萄糖基-7-羟基-3-(4-羟基苯基)-4H-1-苯并吡喃-4-酮, 葛根素
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关于此项目
经验公式（希尔记法）:
C21H20O9
化学文摘社编号:
分子量:
416.38
UNSPSC Code:
12352200
NACRES:
NA.77
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
64198
产品名称
葛根素, ≥98.0% (HPLC)
InChI
1S/C21H20O9/c22-7-14-17(26)18(27)19(28)21(30-14)15-13(24)6-5-11-16(25)12(8-29-20(11)15)9-1-3-10(23)4-2-9/h1-6,8,14,17-19,21-24,26-28H,7H2/t14-,17-,18+,19-,21+/m1/s1
SMILES string
OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c2c(O)ccc3C(=O)C(=COc23)c4ccc(O)cc4
InChI key
HKEAFJYKMMKDOR-VPRICQMDSA-N
assay
≥98.0% (HPLC)
form
powder
Quality Level
Gene Information
mouse ... Aldh1a2(19378), Maoa(17161)
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Biochem/physiol Actions
葛根的异黄酮成分。减轻与酒精戒断相关的焦虑症状。
Packaging
无底玻璃瓶。内含物装在插入的融合锥内。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
David H Overstreet et al.
Pharmacology, biochemistry, and behavior, 75(3), 619-625 (2003-08-05)
Because extracts of kudzu have been used as a hangover remedy in China for many centuries, we tested the ability of NPI-031G (puerarin), an isoflavone isolated from kudzu, to counteract anxiogenic effects associated with withdrawal from chronic alcohol exposure. NPI-O31G
Benguo Liu et al.
Journal of agricultural and food chemistry, 60(51), 12501-12507 (2012-12-12)
Puerarin is a natural isoflavone, found in the Chinese medicinal plant Ge-gen, with many reported health-promoting properties. However, its low water solubility impedes its application in pharmaceutical and functional food products. This study explores the formation of inclusion complex between
Lin Wang et al.
Human & experimental toxicology, 32(2), 172-185 (2013-01-15)
Puerarin (PU), a natural flavonoid, has been reported to possess anti-oxidative and anti-inflammatory activities. In the present study, female Sprague-Dawley rats received lead (Pb) nitrate (300 mg/L, via drinking water) and/or PU (400 mg/kg/day, orally) to investigate the protective effects of PU
Feng Tian et al.
Neuroscience letters, 543, 64-68 (2013-04-11)
Puerarin extracted from radix puraeriae is shown to exert a variety of pharmacological effects including neuroprotective properties. However, its mechanisms of action are needed to further explore. The study was designed to investigate the mechanism of puerarin treatment of acute
Rong Li et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 52, 69-75 (2012-11-14)
This study was designed to evaluate the potential effects of puerarin (PR), an effective isoflavonoid compound purified from Pueraria lobata, in treating hepatic fibrosis (HF) rats induced by carbon tetrachloride (CCl(4), 2 mL kg(-1) d(-1)). Compared to model control, PR
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