82669
1-Pyrenebutyric hydrazide
suitable for fluorescence, ≥97.0% (T)
别名:
4-(1-Pyrenyl)butyric hydrazide
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关于此项目
经验公式（希尔记法）:
C20H18N2O
化学文摘社编号:
分子量:
302.37
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352125
MDL number:
Quality Segment
assay
≥97.0% (T)
form
solid
mp
167-171 °C
suitability
suitable for fluorescence
SMILES string
NNC(=O)CCCc1ccc2ccc3cccc4ccc1c2c34
InChI
1S/C20H18N2O/c21-22-18(23)6-2-3-13-7-8-16-10-9-14-4-1-5-15-11-12-17(13)20(16)19(14)15/h1,4-5,7-12H,2-3,6,21H2,(H,22,23)
InChI key
SOPPDVMSOKMZOC-UHFFFAOYSA-N
General description
1-Pyrenebutyric hydrazide (PBH) finds biological/medical applications in the detection, labeling, and quantification of biological carbonyl compounds including aldehydes and/or ketones and carboxylic acids. It is also industrially used in chemo-sensor materials, lubricants, etc.
Application
1-Pyrenebutyric hydrazide may be used as a fluorescence derivatization reagent in the following:
- Determination of succinylacetone (SA) in urine samples of hepatorenal tyrosinemia patients using high-pressure liquid chromatography with fluorescence detection (HPLC-FLD).
- Determination of glutaric and 3-hydroxyglutaric acids in urine of glutaric acidemia type I patients using HPLC technique with intramolecular excimer-forming fluorescence derivatization.
Other Notes
Fluorescent labeling reagent for carbonyl compounds, e.g. cyclobutanones formed on food irradiation; Labeling of other compounds
signalword
Warning
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves