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Merck
CN

84797

聚(乙二醇)

greener alternative

BioUltra, 2,000

别名:

PEG

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关于此项目

线性分子式:
H(OCH2CH2)nOH
化学文摘社编号:
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352104
MDL number:
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产品名称

聚(乙二醇), BioUltra, 2,000

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

SMILES string

C(CO)O

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

product line

BioUltra

form

powder

mol wt

Mr 1900-2200

greener alternative product characteristics

Safer Solvents and Auxiliaries
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

impurities

insoluble matter:, passes filter test
≤0.001% peroxides (as H2O2):

pH

5.5-7.0 (25 °C, 50 mg/mL in H2O)

mp

50-53 °C

solubility

H2O: 50 mg/mL at 25 °C, clear, colorless

anion traces

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤50 mg/kg

cation traces

Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤200 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Na: ≤200 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

λ

50 mg/mL in H2O

UV absorption

λ: 260 nm Amax: ≤0.1
λ: 280 nm Amax: ≤0.04

greener alternative category

Quality Level

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Application

聚乙二醇用于:
  • 作为制备液体干燥剂溶液的成分
  • 作为蛋白质结晶中的沉淀剂和添加剂
  • 作为代表性的生物相容性聚合物,可在分子水平上解释其与细胞系统的相互作用

General description

聚(乙二醇)(PEG)是非离子型亲水聚合物,可获得不同的分子量形式。它有助于蛋白和核酸的纯化和晶体生长。PEG和葡聚糖一起产生生物材料纯化所需的聚合物双水相体系。PEG还可与细胞膜相互作用,从而促进细胞融合。它具有隐身效果,以及延长的血液循环和出色的生物相容性。PEG能过通过刺激补体途径引起超敏反应。
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. Polyethylene glycol (PEG) is an eco-friendly, biodegradable polymer widely used in pharmaceuticals and cosmetics. Its non-toxic nature and versatility make it a sustainable choice, derived from renewable resources, contributing to greener product formulations. Click here for more information.

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

281.5 °F - closed cup

flash_point_c

138.6 °C - closed cup

ppe

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Influence of osmotic drying with an aqueous poly (ethylene glycol) liquid desiccant on alumina objects gelcast with gelatin
Hammel EC, et al.
Ceramics International, 43(18), 16443-16450 (2017)
Poly(Ethylene Glycol) Chemistry: Biotechnical and Biomedical Applications (2013)
Exploring carbon nanomaterial diversity for nucleation of protein crystals
Govada L, et al.
Scientific Reports, 6(18), 20053-20053 (2016)
Crystal Structures of Membrane Transporter MmpL3, an Anti-TB Drug Target
Zhang B, et al.
Cell, 176(3), 636-648 (2019)
Li Xu et al.
Biomaterials, 147, 1-13 (2017-09-20)
As the gold standard polymer for drug delivery system, polyethylene glycol (PEG) has excellent biocompatibility. It's reported that the low nonspecific interactions between PEG and body contribute to its biocompatibility. However, here we discover dynamic biological interactions exist between PEG

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