85976
甲氧基聚乙二醇琥珀酸酯N-羟基琥珀酰亚胺
5,000, ≥90%
别名:
单-甲基聚乙二醇琥珀酸酯N-琥珀酰亚胺酯, PEG-琥珀酰亚胺琥珀酸酯, 甲氧基聚乙二醇5000琥珀酸N-琥珀酰亚胺酯
SMILES string
N1(C(=O)CCC1=O)OC(=O)CCC(=O)COCCO
InChI
1S/C11H15NO7/c13-5-6-18-7-8(14)1-4-11(17)19-12-9(15)2-3-10(12)16/h13H,1-7H2
InChI key
OVPTZXRXNNJKSJ-UHFFFAOYSA-N
assay
≥90%
form
powder
storage temp.
−20°C
Quality Level
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Application
- 用于药物位点特异性释放并增强肿瘤积聚的基质金属蛋白酶-2/9敏感性肽偶联聚合物胶束：制备与体外和体内评估。该研究探讨了甲氧基聚乙二醇琥珀酸N-羟基琥珀酰亚胺酯 （MPEG-S-NHS）在对基质金属蛋白酶-2/9敏感的肽偶联聚合物胶束制备中的用途。这些胶束是为位点特异性药物释放和增强肿瘤靶向性而设计，展示出在先进药物递送系统中的应用前景（Zhang X, Wang X, Zhong W, Ren X, Sha X, Fang X, 2016）[链接]。
Other Notes
Shearwater Polymers 的产品
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
M A Croyle et al.
Journal of virology, 75(10), 4792-4801 (2001-04-20)
Most of the early gene therapy trials for cystic fibrosis have been with adenovirus vectors. First-generation viruses with E1a and E1b deleted are limited by transient expression of the transgene and substantial inflammatory responses. Gene transfer is also significantly curtailed
Georgi As Georgiev et al.
Colloids and surfaces. B, Biointerfaces, 59(2), 184-193 (2007-06-26)
Foam thin liquid films (TLF) and monolayers at the air-water interface formed by DMPC mixed with DMPE-bonded poly (ethylene glycol)s (DMPE-PEG(550), DMPE-PEG(2000) and DMPE-PEG(5000)) were obtained. The influence of both (i) PEG chain size (evaluated in terms of Mw) and
G Sirokmán et al.
Protein science : a publication of the Protein Society, 2(7), 1161-1170 (1993-07-01)
Bacteriorhodopsin (BR), from the purple membrane (PM) of Halobacterium halobium, was chemically modified with methoxypolyethylene glycol (m-PEG; molecular weight = 5,000 Da) succinimidyl carbonate. The polyethylene glycol-bacteriorhodopsin (m-PEG-SC-BR33) conjugate, containing one polyethylene glycol chain, was water soluble. The secondary structure
Y P Li et al.
Acta pharmacologica Sinica, 22(6), 549-555 (2001-12-19)
To assess the merits of polyethylene glycol-modified recombinant human tumor necrosis factor alpha (PEG-rHuTNF-alpha). The rHuTNF-alpha was modified with N-succinimidyl succinate monomethoxy polyethylene glycol (SS-PEG) of three different molecular weights. The PEG-rHuTNF-alpha was separated into fractions of various molecular weights
H Matsuyama et al.
Chemical & pharmaceutical bulletin, 39(3), 743-746 (1991-03-01)
Phospholipase D from Streptomyces sp. AA586, PLDP, was modified with methoxypolyethylene glycol succinimidylsuccinate (ss-PEG), an active derivative of polyethylene glycol. By titration with trinitrobenzene sulfonate (TNBS), approximately 70% of the free amino groups in the enzyme protein were shown to
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