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Merck
CN

85976

甲氧基聚乙二醇琥珀酸酯N-羟基琥珀酰亚胺

5,000, ≥90%

别名:

单-甲基聚乙二醇琥珀酸酯N-琥珀酰亚胺酯, PEG-琥珀酰亚胺琥珀酸酯, 甲氧基聚乙二醇5000琥珀酸N-琥珀酰亚胺酯

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关于此项目

化学文摘社编号:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.25
MDL number:
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Quality Segment

assay

≥90%

form

powder

storage temp.

−20°C

SMILES string

N1(C(=O)CCC1=O)OC(=O)CCC(=O)COCCO

InChI

1S/C11H15NO7/c13-5-6-18-7-8(14)1-4-11(17)19-12-9(15)2-3-10(12)16/h13H,1-7H2

InChI key

OVPTZXRXNNJKSJ-UHFFFAOYSA-N

Application


  • 用于药物位点特异性释放并增强肿瘤积聚的基质金属蛋白酶-2/9敏感性肽偶联聚合物胶束:制备与体外和体内评估。该研究探讨了甲氧基聚乙二醇琥珀酸N-羟基琥珀酰亚胺酯 (MPEG-S-NHS)在对基质金属蛋白酶-2/9敏感的肽偶联聚合物胶束制备中的用途。这些胶束是为位点特异性药物释放和增强肿瘤靶向性而设计,展示出在先进药物递送系统中的应用前景(Zhang X, Wang X, Zhong W, Ren X, Sha X, Fang X, 2016)[链接]


Other Notes

Shearwater Polymers 的产品


存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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M A Croyle et al.
Journal of virology, 75(10), 4792-4801 (2001-04-20)
Most of the early gene therapy trials for cystic fibrosis have been with adenovirus vectors. First-generation viruses with E1a and E1b deleted are limited by transient expression of the transgene and substantial inflammatory responses. Gene transfer is also significantly curtailed
H Matsuyama et al.
Chemical & pharmaceutical bulletin, 39(3), 743-746 (1991-03-01)
Phospholipase D from Streptomyces sp. AA586, PLDP, was modified with methoxypolyethylene glycol succinimidylsuccinate (ss-PEG), an active derivative of polyethylene glycol. By titration with trinitrobenzene sulfonate (TNBS), approximately 70% of the free amino groups in the enzyme protein were shown to
Y P Li et al.
Acta pharmacologica Sinica, 22(6), 549-555 (2001-12-19)
To assess the merits of polyethylene glycol-modified recombinant human tumor necrosis factor alpha (PEG-rHuTNF-alpha). The rHuTNF-alpha was modified with N-succinimidyl succinate monomethoxy polyethylene glycol (SS-PEG) of three different molecular weights. The PEG-rHuTNF-alpha was separated into fractions of various molecular weights



全球贸易项目编号

货号GTIN
85976-250MG04061832887746
85976-1G04061826271254