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Merck
CN

87333

聚(乙二醇)

greener alternative

BioUltra, 600

别名:

PEG

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线性分子式:
H(OCH2CH2)nOH
化学文摘社编号:
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352104
MDL number:
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产品名称

聚(乙二醇), BioUltra, 600

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

SMILES string

C(CO)O

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

product line

BioUltra

form

liquid (or viscous liquid or paste)

mol wt

Mr 570-630

Quality Level

greener alternative product characteristics

Safer Solvents and Auxiliaries
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

impurities

insoluble matter:, passes filter test
≤0.002% peroxides (as H2O2)

refractive index

n20/D 1.469

pH

5.5-7.0 (25 °C, 50 mg/mL in H2O)

mp

17-22 °C (lit.)

solubility

H2O: 50 mg/mL at 25 °C, clear, colorless

density

1.13 g/mL at 20 °C

anion traces

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤50 mg/kg

cation traces

Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤500 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Na: ≤200 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

λ

50 mg/mL in H2O

UV absorption

λ: 260 nm Amax: 0.06
λ: 280 nm Amax: 0.03

greener alternative category

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Application


  • 用于鉴定3D聚乙二醇水凝胶内间充质干细胞基质组的非标记定量蛋白质组学。: 该研究重点介绍了聚乙二醇水凝胶在非标记定量蛋白质组学法间充质干细胞基质组研究中的用途,提供了有关细胞-基质相互作用和组织工程的见解(Devaud et al., 2018)。

  • 用于伤口愈合的生物玻璃活化白蛋白水凝胶: 该研究展示了用于改善伤口愈合过程的有效材料PEG基生物玻璃活化水凝胶,显示了其生物相容性和再生潜力(Zhou et al., 2018)。

  • 甲氧基聚乙二醇聚丙交酯-乙交酯携带的阿霉素和紫杉醇优于传统药物递送方法。: 该论文讨论了聚乙二醇化药物递送系统在癌症治疗功效和减少副作用方面优于传统方法之处(Hu et al., 2018)。

  • 来源于牙髓干细胞的软骨形成细胞在一型和二型C胶原蛋白水凝胶中具有差异性细胞运动能力。: 该研究探索了来源于干细胞的软骨形成细胞在聚乙二醇修饰的胶原蛋白水凝胶中的差异性运动(differential motility),提供了有关再生医学应用的见解(Yao and Flynn, 2018)。

General description

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. Polyethylene glycol (PEG) is an eco-friendly, biodegradable polymer widely used in pharmaceuticals and cosmetics. Its non-toxic nature and versatility make it a sustainable choice, derived from renewable resources, contributing to greener product formulations. Click here for more information.

存储类别

10 - Combustible liquids

wgk

WGK 1

flash_point_f

281.5 °F - closed cup

flash_point_c

138.6 °C - closed cup

ppe

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Mark A Rice et al.
Acta biomaterialia, 5(1), 152-161 (2008-09-17)
Ultrasound has potential as a non-destructive analytical technique to provide real-time online assessments of matrix evolution in cell-hydrogel constructs used in tissue engineering. In these studies, chondrocytes were encapsulated in poly(ethylene glycol) hydrogels, and gel degradation was manipulated to provide
Idalis Villanueva et al.
Acta biomaterialia, 5(8), 2832-2846 (2009-06-11)
The pericellular matrix (PCM) surrounding chondrocytes is thought to play an important role in transmitting biochemical and biomechanical signals to the cells, which regulates many cellular functions including tissue homeostasis. To better understand chondrocytes interactions with their PCM, three-dimensional poly(ethylene
I L Konorova et al.
Patologicheskaia fiziologiia i eksperimental'naia terapiia, (4)(4), 7-9 (1991-07-01)
The search for antiaggregatory compounds is undertaken, as a rule, under in vitro conditions which do not reflect the dynamics of the real process. The present work deals with study of the peculiarities of the development of the collagen induced
P I Polimeni et al.
Journal of cardiovascular pharmacology, 14(3), 374-380 (1989-09-01)
The acute hemodynamic effects of an intravenously (i.v.) injected poly(ethylene oxide), Polyox WSR N-60K (dose 50 mg/kg), were studied in the open-chest rat anesthetized with sodium pentobarbital. The injectate is one of four drag-reducing polymers known to augment in vitro
M Patel Geeta et al.
Current drug delivery, 6(2), 159-165 (2009-05-20)
Carbamazepine indicated for the control of epilepsy, undergoes extensive hepatic first-pass metabolism after oral administration. A vaginal dosage form of carbamazepine is not commercially available. Conventional suppository having poor retention in the vaginal tract, as they are removed in a

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