87809
视黄醇丙酸酯
≥98.0% (sum of isomers, HPLC), ~2500 U/mg
别名:
维生素A丙酸酯
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关于此项目
经验公式（希尔记法）:
C23H34O2
化学文摘社编号:
分子量:
342.51
NACRES:
NA.79
PubChem Substance ID:
eCl@ss:
34058020
UNSPSC Code:
12352205
EC Number:
230-363-2
MDL number:
Beilstein/REAXYS Number:
2475675
InChI key
SFRPDSKECHTFQA-ONOWFSFQSA-N
InChI
1S/C23H34O2/c1-7-22(24)25-17-15-19(3)11-8-10-18(2)13-14-21-20(4)12-9-16-23(21,5)6/h8,10-11,13-15H,7,9,12,16-17H2,1-6H3/b11-8+,14-13+,18-10+,19-15+
SMILES string
CCC(=O)OC\C=C(C)\C=C\C=C(C)\C=C\C1=C(C)CCCC1(C)C
biological source
synthetic
assay
≥98.0% (sum of isomers, HPLC)
form
liquid
specific activity
~2500 U/mg
contains
BHT as stabilizer
impurities
~5% cis-isomers
color
green-yellow to very dark green-yellow, yellow to very dark yellow
storage temp.
2-8°C
Quality Level
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General description
视黄醛、视黄醇和视黄酸是维生素A的醛、醇和酸形式。由于脂肪链中的不饱和键，类视黄醇的几何异构体较多。类视黄醇还存在视黄醇酯形式，如视黄醇丙酸酯、视黄醇乙酸酯和视黄醇棕榈酸酯。
Application
视黄醇丙酸酯用于测定其对蛋用鹌鹑的性能、蛋品质、血清和蛋氧化状态以及维生素A水平的影响。
Biochem/physiol Actions
视黄醇酯是维生素A的存储池，可根据需要转换为视黄醇和其他类视黄醇物质。 视黄醇丙酸酯在各种配方中用于除皱。
Other Notes
相当于Ph Eur II, 217(1983)的1个国际单位
signalword
Danger
hcodes
Hazard Classifications
Aquatic Chronic 4 - Repr. 1B
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 2
flash_point_f
262.4 °F - closed cup
flash_point_c
128 °C - closed cup
ppe
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
J J J Fu et al.
The British journal of dermatology, 162(3), 647-654 (2010-04-09)
Tretinoin is considered the benchmark prescription topical therapy for improving fine facial wrinkles, but skin tolerance issues can affect patient compliance. In contrast, cosmetic antiwrinkle products are well tolerated but are generally presumed to be less efficacious than tretinoin. To
Effect of retinol and retinol esters on performance, egg quality, and blood and egg vitamin A levels in laying quails
Ilhan M and BULBUL T
Turkish Journal of Veterinary and Animal Sciences, 40(5), 590-597 (2016)
Retinyl propionate and climbazole combination demonstrates clinical improvement to the appearance of hyperpigmentation and deep wrinkling with minimal irritation
Hawkins S, et al.
International Journal of Cosmetic Science, 39(6), 589-599 (2017)
C Green et al.
Clinical and experimental dermatology, 23(4), 162-167 (1999-01-23)
The clinical and histological effects of retinyl propionate cream (a retinyl ester) on extrinsic skin ageing (photo-ageing) in man were assessed in a double-blind randomized placebo-controlled study of 80 subjects, individual parameters of this being assessed for each treatment site
S Donoghue et al.
The Journal of nutrition, 115(12), 1562-1571 (1985-12-01)
Twelve ewes were fed retinyl propionate equivalent to 12,000 micrograms retinol/kg body weight per day for the last two trimesters of pregnancy (group fed high vitamin A). Four ewes received a control level of 120 micrograms/kg body weight per day.
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