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Merck
CN

90101

Ampliflu Red

suitable for fluorescence, ≥98.0% (HPLC)

别名:

10-乙酰基-3,7-二羟基吩噁嗪

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关于此项目

经验公式(希尔记法):
C14H11NO4
化学文摘社编号:
分子量:
257.24
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352108
MDL number:
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产品名称

Ampliflu Red, suitable for fluorescence, ≥98.0% (HPLC)

InChI key

PKYCWFICOKSIHZ-UHFFFAOYSA-N

SMILES string

CC(=O)N1c2ccc(O)cc2Oc3cc(O)ccc13

InChI

1S/C14H11NO4/c1-8(16)15-11-4-2-9(17)6-13(11)19-14-7-10(18)3-5-12(14)15/h2-7,17-18H,1H3

assay

≥98.0% (HPLC)

form

powder

Quality Level

mol wt

257.24 g/mol

concentration

90-100 % (w/w) (Ampliflu Red)

color

slightly brown-red
white to slightly brown

solubility

water: slightly soluble at 20 °C

fluorescence

λex 571 nm; λem 585 nm in DMSO

suitability

suitable for fluorescence

storage temp.

2-8°C

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Application

Ampliflu Red 已被用于研究帕金森病相关的线粒体异常和氧化应激。Ampliflu Red 检测适合作为 hTPO(人甲状腺过氧化物酶)活性抑制的替代指标检测。磷脂酶 D 是一种重要的细胞过程成分,使用 Ampliflu Red(10-乙酰-3,7-二羟基苯恶嗪)测定其活性。Ampliflu Red 用于以下应用:
  • 炎症介质的定量
  • 测定游离和酯化的胆固醇含量
  • 评价化合物作为 GABA-AT 化合物的底物

Legal Information

Ampliflu is a trademark of Sigma-Aldrich Co. LLC

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Fourteen polyamine analogues, asymmetric or symmetric substituted spermine (1-9) or methoctramine (10-14) analogues, were evaluated as potential inhibitors or substrates of two enzymes of the polyamine catabolic pathway, spermine oxidase (SMOX) and acetylpolyamine oxidase (PAOX). Compound 2 turned out to
Barae Jomaa et al.
ALTEX, 32(3), 191-200 (2015-03-31)
A simple and rapid luminometric assay for the detection of chemical inhibitors of human thyroid peroxidase (hTPO) activity was developed and validated with 10 model compounds. hTPO was derived from the human thyroid follicular cell line Nthy-ori 3-1 and its
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Bioorganic & medicinal chemistry, 20(19), 5763-5773 (2012-09-05)
Two principal neurotransmitters are involved in the regulation of mammalian neuronal activity, namely, γ-aminobutyric acid (GABA), an inhibitory neurotransmitter, and L-glutamic acid, an excitatory neurotransmitter. Low GABA levels in the brain have been implicated in epilepsy and several other neurological
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Gentamicin is an aminoglycoside antibiotic commonly used for treating Pseudomonas infections, but its use is limited by a relatively short half-life. In this investigation, developed a controlled-release gentamicin formulation using poly(lactide-co-glycolide) (PLGA) nanoparticles. We demonstrate that entrapment of the hydrophilic
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Phospholipase D plays a key role in the biosynthesis of phosphatidic acid, a second messenger involved in essential cellular processes. Oleate-activated phospholipase D was the first mammalian phospholipase D isoform to be discovered but is the least known. The study

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