Merck
CN

93205

Sigma-Aldrich

β-磷酸烟酰胺腺嘌呤二核苷酸 二钠盐

≥97% (calc. based on dry substance, enzymatic)

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别名:
β-NADH磷酸 二钠盐, β-NADP-Na2, 三磷酸吡啶核苷酸 二钠盐
经验公式(希尔记法):
C21H26N7Na2O17P3
CAS号:
分子量:
787.37
EC 号:
MDL编号:
PubChem化学物质编号:
NACRES:
NA.51

检测方案

≥97% (calc. based on dry substance, enzymatic)

形式

powder

杂质

≤7% water

痕量阳离子

Ca: ≤1000 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤20 mg/kg
K: ≤1000 mg/kg
Mg: ≤500 mg/kg
Mn: ≤350 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤50 mg/kg

储存温度

−20°C

SMILES string

[Na+].[Na+].NC(=O)c1ccc[n+](c1)C2O[C@H](COP([O-])(=O)OP([O-])(=O)OC[C@H]3O[C@H]([C@H](OP(O)([O-])=O)[C@@H]3O)n4cnc5c(N)ncnc45)[C@@H](O)[C@H]2O

InChI

1S/C21H28N7O17P3.2Na/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(44-46(33,34)35)14(30)11(43-21)6-41-48(38,39)45-47(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32;;/h1-4,7-8,10-11,13-16,20-21,29-31H,5-6H2,(H7-,22,23,24,25,32,33,34,35,36,37,38,39);;/q;2*+1/p-2/t10-,11-,13-,14-,15-,16-,20?,21-;;/m1../s1

InChI key

WSDDJLMGYRLUKR-FHQWUTKFSA-L

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应用

磷酸烟酰胺腺嘌呤二核苷酸(NADP)和NADPH形成氧化还原对。 NADP/NADPH是辅酶,支持许多应用中电子转移的氧化还原反应,尤其是脂和核酸合成的厌氧反应。NADP/NADPH在各种细胞色素P450体系和氧化酶/还原酶反应体系,比如硫氧还蛋白还原酶/硫氧还蛋白系统中都是辅酶对。

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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Thioredoxin reductase (TRX) is a selenoprotein that reduces oxidized protein substrates in an NADPH-dependent process (cf. Fig. 1). The thioredoxins (TX) are a family of small redox active proteins that undergo reversible oxidation/reduction and help to maintain the redox state
Augusto C Montezano et al.
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Imad Al Ghouleh et al.
Free radical biology & medicine, 51(7), 1271-1288 (2011-07-05)
Reactive oxygen species (ROS) are involved in numerous physiological and pathophysiological responses. Increasing evidence implicates ROS as signaling molecules involved in the propagation of cellular pathways. The NADPH oxidase (Nox) family of enzymes is a major source of ROS in
Sang-Choul Im et al.
Archives of biochemistry and biophysics, 507(1), 144-153 (2010-11-09)
Cytochrome P450 2B4 is a microsomal protein with a multi-step reaction cycle similar to that observed in the majority of other cytochromes P450. The cytochrome P450 2B4-substrate complex is reduced from the ferric to the ferrous form by cytochrome P450
Snigdha Shaw et al.
Scientific reports, 10(1), 3458-3458 (2020-02-28)
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